SCIENTIFIC FOCUS VASCULAR DISEASES
SPEAKER
Univ.-Prof. Dr. Oliver Söhnlein
Institute for Experimental Pathology, ZMBE
Funded projects
- Li1/012/24 - Rescuing contractile deficiency of failing cardiomyocytes by restoring titin protein expression
Principal investigator: Wolfgang A. Linke
Funding period: 01/2024 - 12/2026
completed IZKF Projects - Scientific Focus Vascular Diseases
- Soe1/001/22 - The contribution of neutrophils to infection-accelerated atherosclerosis
Principal investigator: Oliver Söhnlein
Funding period: 01/2022 - 12/2024 - Mat1/027/21 - Mechanobiology of the planar cell polarity signaling pathway during angiogenesis
Prinicipal Investigator: Maja Matis
Funding period: 01/21 - 12/23 - Li1/029/20 - Elucidating the role of truncated titin proteins in the pathomechanism of dilated cardiomyopathy due to TTN-truncating mutations
Principal investigator: Wolfgang A. Linke
Funding period: 01/20 - 06/23 - Kha1/002/20 - New therapeutic approaches for GFI1-36N expressing leukaemia
Principal investigator: Cyrus Khandanpour
Funding period: 01/20 - 12/22 - Kief1/019/20 - Assessing macrophage activation, migration and fate during a novel anti-atherosclerotic intervention
Principal investigator: Friedemann Kiefer
Funding period: 01/20 - 12/22 - Art1/019/18 - Identification of target genes for novel therapies for high-risk acute myeloid leukaemia (AML) patients via systematic CRISPR-based genetic screening
Principal investigator: Maria Francisca Arteaga Paz
Funding period: 01/18 - 12/20 - Mü1/011/17 - Inhibition of adenylylcyclase 5 by annexin A4 uand its role in cardiac remodeling
Principal investigator: Frank Ulrich Müller
Funding period: 1/2017 - 12/2019 - Bet1/013/17 - Effect of endothelial mechanics on leukocyte guidance and transmigration
Principal investigators: Timo Betz, Volker Gerke
Funding period: 1/2017 - 12/2019 - Rö1/009/15 - Combination of Chimeric Antigen Receptor (CAR) technology with retargeted tissue factor as cell mediated tumor therapy
Principal investigators: Claudia Rössig, Christoph Schliemann, Wolfgang E. Berdel
Funding period: 1/2015 - 12/2014 - See1/012/13 - Virus induced modulation of cardiac potassium channels as possible cause of viral myocarditis associated arrhythmias
Principal investigator: Guiscard Seebohm
Funding period:1/2013 - 12/2015 - Wa1/008/12 - Signal transduction defects in hypercholesterolemia-induced monocyte dysfunction
Principal investigator: Johannes Waltenberger
Funding period: 1/2012 - 10/2015 - Schu1/011/12 - Genomics of human myocardial repolarisation
Principal investigator: Eric Schulze-Bahr
Funding period: 1/2012 - 10/2015 - Mü1/014/11 - Relevance of cAMP-dependent transcription factors for heart failure associated arrhythmias
Principal investigators: Frank Ulrich Müller, Wilhelm Schmitz
Funding period: 1/2011 - 10/2014 - Ru1/022/08 - Genetics of arterial calcification
Principal investigator: Frank Rutsch
Funding period: 1/2008 - 10/2011 - Bra1/001/08 - Cellular and molecular characterization of granulocyte colony-stimulating factor(G-CSF)-mediated regeneration in infarcted heart and brain
Principal investigator: Eva Brand
Funding period: 1/2008 - 12/2010 - Pa1/011/08 - The role of the chemokine receptor CCR10 for the structure and function of arterial vessels
Principal investigator: Hermann-Joseph Pavenstädt
Funding period: 1/2008 - 12/2010 - Nik1/032/08 - Cellular and molecular characterization of granulocyte colony-stimulating factor(G-CSF)-mediated regeneration in infarcted heart and brain
Principal investigators: Sigrid Nikol, Wolf-Rüdiger Schäbitz
Funding period: 1/2008 - 12/2009 - Mü1/004/07 - Role of CREB/CREM/ATF1 transcription factors in the NO/cGMP-dependent regulation of vascular function
Principal investigators: Frank Ulrich Müller, Wilhelm Schmitz
Funding period: 1/2007-10/2010 - Keh1/037/07 - Candida Infection of the vascular compartments: Interaction between fungi, platelets and endothelial cells
Principal investigators: Beate Kehrel, Christof von Eiff, Andreas Uekötter
Funding period: 1/2007 -10/2010 - Kih1/010/07 - Activation of brain-type Na+ channels in the myocardium: a new therapeutic principle for positive inotropic non-toxic scorpion peptides in humans
Principal investigators: Uwe Kirchhefer, Larissa Fabritz
Funding period: 1/2007- 12/2009 - Schu1/031/07 - Molecular genetics of atrial septal defect
Principal investigator: Eric Schulze-Bahr
Funding period: 1/2007- 12/2009 - Schu1/001/04 - Molecular genetics of sinus node disease
Principal investigator: Eric Schulze-Bahr
Funding period: 06/2004 -12/2006 - Mü1/021/04 - Myocardial function and gene expression of ATF-4 deficient mice
Principal investigators: Frank Ulrich Müller, Wilhelm Schmitz
Funding period: 6/2004 -12/2006 - Ko1/031/04 - Molecular in-vivo imaging of apoptosis with SPECT- and PET-compatible small- molecular caspase inhibitors
Principal investigators: Klaus Kopka, Bodo Levkau, Michael Schäfers
Funding period: 6/2004 -12/2006 - Ku1/040/04 - Mechanisms and pathophysiological implications of desensitisation of the ANP receptor (GC-A)
Principal investigator: Michaela Kuhn
Funding period: 6/2004 -12/2006 - The1/068/04 - Anti-inflammatory properties of the thrombomodulin-lectin like domain with regard to tissue-remodelling after global and regional hypoxia – identifucation of ligands and signal tranduction
Principal investigators: Gregor Theilmeier, Hugo van Aken
Funding period: 6/2004 -12/2006 - Ki1/099/04 - Functional relevance of plakoglobin for cardiac function and arrythmias – a molecular model for arrythmogenic right ventricular cardiomyopathy
Principal investigators: Paulus Kirchhof, Thomas Wichter
Funding period: 6/2004 -12/2006 - Bo1/101/04 - Characterisation of a transgenic animal model overexpressing proteinphosphatase 5
Principal investigators: Peter Boknik, Ulrich Gergs, Joachim Neumann
Funding period: 6/2004 -12/2006
- Soe1/001/22 - The contribution of neutrophils to infection-accelerated atherosclerosis