SCIENTIFIC FOCUS NERVOUS SYSTEM DISEASES

SPEAKER
Univ.-Prof. Dr. Dr. Udo Dannlowski
Institut of Translational Psychiatry

Funded projects

  • Lil3/001/25 - Translating novel biomarker findings for neurodegenerative diseases into precision medicine
    Principal investigator: Christina Lill
    Funding period: 01/2025 - 12/2027
  • Ag3/006/25 - The influence of scratching-induced mechanical stress on resident skin cells and their role in nerve fiber sensitization
    Principal investigators: Konstantin Agelopoulos, Sonja Ständer
    Funding period: 01/2025 - 12/2027
  • Lue3/009/25 - CNS intrinsic effects of complement activation: clinical and biological impact
    Principal investigator: Jan Lünemann
    Funding period: 01/2025 - 06/2026
  • Ju3/001/24 - Use of non-invasive brain stimulation to causally investigate the role of depression and anxiety in the tinnitus network
    Principal investigators: Markus Junghöfer, Joachim Groß
    Funding period: 01/2024 - 12/2026
  • KuT3/010/24 - Astrocytes and their interactions with other glial cells are essential for the reparative capacity of MS lesions
    Principal investigators: Tanja Kuhlmann, Luisa Klotz
    Funding period: 01/2024 - 12/2026
  • Zil3/007/23 - Dissecting the polygenic basis of major depression through massively parallel analysis of iPSCs
    Principal investigator: Michael Ziller
    Funding period: 01/2023 - 12/2025

  • completed IZKF Projects - Scientific Focus Nervous System Diseases

    • Dan3/022/22 - Limbic scars - long-term consequences of childhood maltreatment on brain structure and -function
      Principal investigator: Udo Dannlowski
      Funding period: 01/2022 - 12/2024
    • Min3/003/21 - Characterization of a newly identified, disease specific immune cell population: `stroke-associated myeloid cells` (SAMC)
      Principal investigator: Jens Minnerup
      Funding period: 01/2021 - 12/2023
    • Ga3/016/21 - Lipid-dependence of curvature-induced signaling in developing neurons
      Principal investigator: Milos Galic
      Funding period: 01/2021 - 12/2023
    • KuT3/007/20 - Functional consequences of aging for oligodendrocytes: Identification of molecular pathways as target for remyelination promoting therapies in multiple sclerosis
      Principal investigator: Tanja Kuhlmann
      Funding period: 01/2020 - 06/2023
    • MzH3/020/20 - NeuroML - Machine Learning Infrastructure for cerebrospinal fluid-based neurological discovery
      Principal investigator: Gerd Meyer zu Hörste, Tim Hahn
      Funding period: 01/2020 - 06/2023
    • Pog3/027/20 - Using optogenetic probing and fMRI techniques in mice to investigate neuronal pathways relevant for incisional and neuropathic pain-related outcomes
      Principal investigator: Esther M. Pogatzki-Zahn
      Funding period: 01/2020 - 06/2023
    • La3/013/20 - Neuronal network analysis of BDNF mediated prevention of long-lasting stress effects
      Principal investigator: Maren Denise Lange
      Funding period: 01/2020 - 12/2022
    • Ha3/017/20 - Role of ASCL1 in the biology of atypical teratoid/rhabdoid tumors (ATRT)
      Principal investigator: Martin Hasselblatt
      Funding period: 01/2020 - 12/2022
    • Kli3/025/20 - Microstructured and functionalized chips for rapid neuronal differentiation and presynapse formation of human neural precursor cells
      Principal investigator: Jürgen Klingauf
      Funding period: 01/2020 - 10/2022 (terminated 12/2020)
    • Gro3/001/19 - An integrated approach for studying dynamic body-brain interactions: The case of respiration
      Principal investigator: Joachim Groß
      Funding period: 01/2019 - 06/2022
    • Kl3/010/19 - Antigen-specific CD8 T-cell responses in Neuromyelitis Optica and Susac syndrome
      Principal investigators: Luisa Klotz, Catharina Groß
      Funding period: 01/2019 - 06/2022
    • Mi3/004/19 - Defects of synaptic function caused by ASD and PHLS-associated missense mutations in the neurexin-1 gene
      Principal investigator: Markus Missler
      Funding period: 01/2019 - 10/2021
    • Meu3/015/18 - Silent K2P-channels in the immune system: the role of TWIK2-channels in multiple sclerosis
      Principal investigators: Sven Meuth, Petra Hundehege
      Funding period: 01/2018 - 09/2020
    • Dan3/012/17 - Machine learning and pattern recognition in psychiatry - translational approaches in diagnostics and prediction
      Principal investigator: Udo Dannlowski
      Funding period: 01/2017 - 10/2020
    • Jün3/003/17 - Opioid-dependent modulation of fear-relevant connections between the paraventricular thalamic nucleus, the prefrontal cortex and amygdala
    • Principal investigator: Kay Jüngling
      Funding period: 01/2017 - 12/2019
    • Bud3/001/16 - Cell type-specific regulation and therapeutic potential of 2-pore-domain K+ channels in the thalamus
      Principal investigator: Thomas Budde
      Funding period: 01/2016 - 12/2018
    • Alf3/018/16 - The role of the Chemokine receptor CCR4 and its ligand CCL22 in the APP/PS1 mouse model
      Principal investigator: Judith Alferink
      Funding period: 01/2016 - 12/2018
    • KuT3/012/15 - In- and extrinsic signalling pathways modulating oligodendroglial migration
      Principal investigator: Tanja Kuhlmann
      Funding period: 01/2015 - 10/2018
    • Ha3/019/15 - Role of epigenetic alterations in the biology of atypical teratoid/rhabdoid tumors (AT/RT))
      Principal investigator: Martin Hasselblatt
      Funding period: 01/2015 - 10/2018
    • Ju3/024/15 - Transcranial direct current stimulation of the medial prefrontal cortex for therapy of unipolar major depression 
      Principal investigators: Markus Junghöfer, Carsten Wolters, Volker Arolt
      Funding period: 01/2015 - 10/2018
    • Kli3/027/15 - Putative role of endosome-like compartments for synaptic vesicle recycling and presynaptic short-term plasticity
      Principal investigator: Jürgen Klingauf
      Funding period: 01/2015 - 10/2018
    • PaHC3/001/15 - Pathways and mechanisms of NPY and Y2 receptors for controlling conditioned fear
      Principal investigator: Hans-Christian Pape
      Funding period: 01/2015 - 12/2017
    • Zha3/005/14 - The functional relevance of neuron-type-specific Nrg1-III-ErbB4-signaling on defined synapses in prefrontal cortex of mouse
      Principal investigator: Weiqi Zhang
      Funding period: 01/2014 - 10/2017
    • Ru3/006/13 - Functional studies on the role of LM BD1 and ABCD4 in lysosomal cobalamin transport
      Principal investigator: Frank Rutsch
      Funding period: 01/2013 - 10/2016
    • Fa3/016/13 - Imaging networks of the brain by combining multimodal functional imaging with opto-genetic control
      Principal investigator: Cornelius Faber
      Funding period: 01/2013 - 10/2016
    • Meu3/10/12 - The role of NADPH-oxidases in Multiple Sclerosis and its animal model
      Principal investigator: Sven Meuth
      Funding period: 01/2012 - 10/2015
    • Et3/019/12 - The role of the microglia in pathogenesis of age-related macular degeneration
      Principal investigator: Nicole Eter
      Funding period: 01/2012 - 12/2014
    • SchwJ3/001/11 - Regulation of adult neurogenesis by neuroinflammation
      Principal investigator: Jens Schwamborn
      Funding period: 01/2011 - 12/2013
    • KuT3/006/11 - Modulation of Wnt-ß−catenin pathway to promote remyelination
      Principal investigator: Tanja Kuhlmann
      Funding period: 01/2011 - 10/2014
    • Wie3/011/11 - The role of the co-inhibitory B7-H1/PD1 pathway in immune-regulation related to neuroinflammation: mechanisms and therapeutic modulation by high affinity mutant B7-H1 Ig proteins
      Principal investigator: Heinz Wiendl
      Funding period: 01/2011 - 12/2013
    • Ha3/016/11 - Molecular pathogenesis of atypical teratoide/rhabdoid tumors (ATRT)
      Principal investigator: Martin Hasselblatt
      Funding period: 01/2011 - 10/2014
    • PaHC3/003/10 - The Neuropeptide S (NPS) system: properties of NPS neurons and mechanisms of receptor activation
      Principal investigators: Hans-Christian Pape, Kay Jüngling
      Funding period: 01/2010 -12/2012
    • Bud3/0101/10 - New players in the thalamus: physiological and pathophysiological relevance of KCNQ channels
      Principal investigator: Thomas Budde
      Funding period: 01/2010 -10/2013
    • Do3/021/10 - Dysfunctional corticolimbic interaction and its modulation by repetitive transcranial magnetic stimulation (rTMS) in anxiety - emotional word learning as trait marker for anxiety disorders
      Principal investigators: Christian Dobel, Peter Zwanzger
      Funding period: 01/2010 -12/2012
    • Tha3/002/09 - New neuroregenerative strategies at the injured optic nerve in vivo: the use of embryonic neural progenitor cells
      Principal investigator: Solon Thanos
      Funding period: 01/2009 - 12/2011
    • Stei3/034/09 - Relevance of cytokine receptors in the sensory nervous system: cellular communication of the neuronal cytokine receptor interleukin -31 RA and ion channels during inflammation and pain
      Principal investigator: Martin Steinhoff
      Funding period: 01/2009 - 12/2011
    • Floe3/004/08 - Ecogenetic context: Effect of genetic predisposition and environmental factors on memory function in the elderly 
      Principal investigator: Agnes Flöel
      Funding period: 01/2008 - 12/2010
    • Mi3/025/08 - Impaired synaptic function in autism spectrum disorders: role of neurexophilins in regulating neurotransmission
      Principal investigator: Markus Missler
      Funding period: 01/2008 - 10/2011
    • Pan3/008/07 - Integration of magnetoencephalographic (MEG) and functional magnetic resonance imaging (fMRI) studies in somato-sensory perception and executive control as de-pending on the serotonergic and dopaminergic system
      Principal investigators: Christo Pante, Katharina Domschke
      Funding period: 01/2007 - 10/2010
    • Bud3/005/07 - Control of Gq-Proten dependent signal processing in the thalamocortical system with respect to new strategies for the therapy of absence epilepsy
      Principal investigators: Thomas Budde, Thomas Seidenbecher
      Funding period: 01/2007- 12/2009
    • Hen3/003/06 - The role of locus coeruleus degeneration for neuroinflammatory and neurodegnerative mechanisms in Alzheimer’s disease
      Principal investigators: Michael Heneka, Hans-Christian Pape
      Funding period: 01/2006 - 12/2008
    • You3/016/06 - Molecular aspects of neuronal degeneration in the peripheral nervous system: impact of demyelination on gene regulation in neurons
      Principal investigator: Peter Young
      Funding period: 01/2006 - 12/2008
    • Kie3/071/04 - Characterisation of functional differences between resident microglial cells and hematogenous macrophages in the pathophysiology of focal cerebral ischemia in vivo
      Principal investigator: Reinhard Kiefer
      Funding period: 06/2004 - 12/2005
    • Tha3/005/04 - Molecular mechanisms of neuronal regeneration: The role of growth-associated proteins (GAP) and integrins in newly developed animal mutants and primates
      Principal investigator: Solon Thanos
      Funding period: 06/2004 - 12/2006
    • Bro3/054/04 - Small RNAs in neuropsychiatric diseases
      Principal investigators: Jürgen Brosius, Boris Skryabin
      Funding period: 06/2004 - 12/2006
    • Küh3/064/04 - Analysis of the reciprocal assembly/disassembly pathways during neuroepithelial spread of Herpes simplex-Virus Typ 1 (HSV-1)
      Principal investigator: Joachim Kühn
      Funding period: 06/2004 - 12/2006
    • Kne3/074/04 - Boosting of learning with dopamine
      Principal investigators: Stefan Knecht, Catarina Breitenstein
      Funding period: 06/2004 - 12/2006
    • Ker3/086/04 - The proteolipid complex S100A9-GM2AP-GM2 causes glial cytotoxicity in Multilpe Sclerosis
      Principal investigator: Claus Kerkhoff
      Funding period: 06/2004 - 12/2006