Clinical Translation Start Trials - ClinicStarT

In the framework of promoting translational research, the IZKF Münster has developed innovative concepts to close the gap between funding basic research (e.g. mouse studies) and patient-centred research.
Since 2019, the "ClinicStarT" programme funds innovative concepts and science-driven ideas for clinical studies that will later be transferred to external funding programmes. These include clinical observation studies, early clinical feasibility studies (proof of concept) and first pilot studies on patients, which should bring knowledge from basic research and animal experiments into clinical trials.

Funded clinical trials

  • CST/006/24 - A Randomized Controlled Study Investigating Standard Dose Continuous Renal Replacement Therapy (CRRT) Versus Low-Dose CRRT - Ketzerei Trial
    Principal Investigators: Alexander Zarbock, Noelia Alsonso Gonzalez (BBB Approach)
    Funding period: 01/2024 - 12/2025
  • CST/004/22 - Finding a patient individualized strategy for the initiation of renal re-placement therapy (RRT) in critically ill patients with acute kidney injury (AKI) – an observational trial
    Principal Investigators: Melanie Meersch, Johannes Roth (BBB Approach)
    Funding periodt: 01/2022 - 12/2023
  • CST/003/22 - Effects of a combined supplementation of conjugated linoleic acid (CLA) and probiotics (Vivomixx®/VSL#3) as add-on to a first-line immunotherapy in relapsing-remitting Multiple Sclerosis
    Principal Investigators: Luisa Klotz, Thomas Vogl (BBB Approach)
    Funding period: 04/2023 - 03/2025