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Biomedical Informatics

Bioinformatics research in medicine is a key factor for progress in health research, particularly in cancer research.Medical bioinformatics relies on the evaluation of biological mass data, in which the use of computers in combination with reliable mathematical models and algorithms are prerequisite.In many cooperations with our national and international hospital partners, our institute has gained extensive expertise in dealing with bioinformatical medical research issues. A summary of our portfolio can be found here.

Head of the working group
Dr. Sarah Sandmann-Varghese

Advice & Cooperation

We offer advice and cooperation for the following research topics:

  • DNA-seq (targeted, WES, WGS; matched- and non-matched; color space): variant calling, mutational patterns, clonal evolution, ethnicity, relation,
  • RNA-seq (bulk): expression analysis, fusion genes,
  • Single cell omics (RNA-seq, ATAC-seq): expression analysis, clustering, velocity,
  • Microarrays (SNP, aCGH, gene expression, 850K, 450K): CNV calling, expression analysis, methylation analysis,
  • Bisulfite sequencing (RRBS, WGBS): methylation,
  • ChIP-seq:  transcription factor binding sites, histones,
  • 4C-seq, Hi-C-seq: 3D chromatin structure,
  • ATAC-seq: chromatin structure,
     
  • STARR-seq: enhancer structure,
  • Additionally: pathway analyses, geneset enrichment, data integration and annotation.

Registration for counseling can be done either by e-mail or by phone.

Contact: biomedical.informatics@uni-muenster.de
Phone: +49 (0) 251 / 83 - 5 52 70