Lymphoid follicles within secondary lymphoid organs are anatomically delineated by biological barriers formed by specialized stromal endothelial cells. We previously observed that CD169+ macrophages interact with the stroma in these barriers. We aim to decode the molecular pathways defining these macrophage-stromal cell interactions and their impact in the specific immune responses to blood- and lymph-borne pathogens.
Research area: immunology, phagocyte biology
Noelia Alonso-Gonzalez, PhD
Funding period: July 2020 - June 2024