
© Projekt A10 - R.H. Adams

© Projekt A10 - R.H. Adams

© Projekt A10 - R.H. Aadams

© Projekt A10 - R.H. Aadams

© Projekt A10 - R.H. Aadams
The barrier function of the endothelium is critically required for physiological processes in different organs of the healthy organism and, conversely, disruption of the endothelial barrier is a hallmark of many disease processes. Here, we propose to investigate how the transcription factor Yin Yang 1 (YY1), an important regulator of gene expression and chromatin organization, controls EC behavior and endothelial permeability in the central nervous system and in bone in a comparative fashion.
Research area: Endothelial cell biology
Prof. Dr. Ralf Adams
Funding period: July 2016 - June 2024
Original articles