Completed SEED projects

  • SEED/021/23 - Assessment of the translational potential of Musashi RNA-binding protein inhibition in triple-negative breast cancer
    Group leader: Fabian Troschel
    Dispatching Clinic: Institute of Radiation Therapy Clinic - Radiation Oncology
    Host Institute: Institute of Radiation Therapy Clinic - Radiation Oncology
    Funding period: 01/2023 - 12/2025
  • SEED/020/23 - cAIdiology - Artificial Intelligence for Precision Cardiology
    Group leader: Antonius Büscher
    Dispatching Clinic: Department of Cardiology I: Rhythmology
    Host Institute: Institute of Medical Informatics
    Funding period: 01/2023 - 12/2025
  • SEED/019/23 - Surveillance and characterisation of antimicrobial resistance harbouring plasmids
    Group leader: Vincent van Almisck
    Dispatching Clinic: Department of Cardiology I: Coronary heart disease, Cardiac insufficiency and Angiology
    Host Institute: Institute of Hygiene
    Funding period: 01/2023 - 12/2025
  • SEED/018/23 - Mitigation of JAM-dependent transendothelial and reverse transendothelial migration (rTEM) of T2DM monocytes/macrophages as a novel strategy to decelerate atherosclerosis development in diabetes mellitus
    Group leader: Dilvin Semo
    Dispatching Clinic: Department of Cardiology I: Coronary heart disease, Cardiac insufficiency and Angiology
    Host Institute: Clinic for anaesthesiology, Surgical intensive care medicine and Pain therapy
    Funding period: 01/2023 - 12/2025
  • SEED/017/21 - Development and characterisation of a brain organoid model for a new autosomal recessive inherited defect of cortical malformation
    Group leader: Julia Wallmeier
    Dispatching clinic: Department of General Pediatrics
    Host institute: Max Planck Institute for Molecular Biomedicine
    Projektlaufzeit: 01/2021 - 12/2023
  • SEED/016/21 - Understanding human immune-mediated neuropathies at single cell resolution
    Group leader: Michael Heming
    Dispatching clinic: Division of Neurology
    Host institute: Institute of Medical Informatics
    Funding period: 01/2021 - 12/2023
  • SEED 015/20  - Direct reprogramming of kidney mesenchymal cells into podocytes as a therapeutic strategy for chronic kidney disease
    Group leader: Markus Carl Döser
    Dispatching clinic: Department of Medicine D - Nephrology and Rheumatology
    Host institute: Max-Planck-Institute for Molecular Biomedicine
    Project duration: 01/2020-12/2022
  • SEED 014/20  - The impact of monocyte / macrophage SHP-2 tyrosine phosphatase on diabetes-induced atherosclerosis progression
    Group leader: Marc Dorenkamp
    Dispatching clinic: Department of Cardiovascular Medicine
    Host institute: European Institute for Molecular Imaging
    Project duration: 01/2020-12/2022
  • SEED 013/20  - BRD4 as novel epigenetic vulnerability of early T-cell precursor acute lymphoblastic leukemia (ETP-ALL)
    Group leader: Sebastian Balbach
    Dispatching clinic: Department of Pediatric Hematology and Oncology
    Host institute: Department of Pediatric Hematology and Oncology - Stem cell transplatation
    Project duration: 01/2020-12/2022
  • SEED 12/18 - The influence of platelet migration, thrombopoiesis and platelet subpopulations on the course of inflammation
    Group leader:  Andreas Margraf
    Dispatching clinic: Department of Anaesthesiology, Intensive Care and Pain Therapy
    Host institute: AG Vascular Inflammation and Platelets
    Project duration: 09/2018-08/2021
  • SEED 11/19 - Individualised prediction of the clinical course of affective disorders by the use of integrated clinical and experimental data
    Group leader: Nils Opel
    Dispatching clinic: Department of Mental Health (formerly Department of Psychiatry and Psychotherapy)
    Host institute: Institute of Medical Informatics
    Project duration: 01/2019-12/2021
  • SEED 10/19 - The impact of the calcium-regulated K2P channel TRESK on T-cell functions in experimental stroke
    Group leader: Leoni Rolfes
    Dispatching clinic: Division of General Neurology
    Host institute: Institute for Translational Neurology
    Project duration: 01/2019 - 03/2021 (the project was terminated prematurely since the group leader moved to the University Hospital, Düsseldorf)
  • SEED 09/17 - Interleukin 24 in renal ischemia-reperfusion injury: Analysis of the pathophysiological role and evaluation of potential therapeutic options
    Group leader: Katharina Schütte-Nütgen
    Dispatching clinic: Department of Medicine D - Nephrology and Rheumatology
    Host institute: Institute of Medical Biochemistry (ZMBE)
    Funding period: 01/2017 - 12/2019
  • SEED 07/17 - Leukocyte migration and endothelial integrity in cerebral ischaemia – pathophysiology, interaction, and relevance for outcome and secondary haemorrhage after intravenous thrombolysis
    Group leader: Antje Schmidt-Pogoda
    Dispatching clinic: Division of General Neurology
    Host institute: Max Planck Institute for Molecular Biomedicine
    Funding period: 01/2017 - 12/2019
  • SEED 06/15 - Analysis of the regulation of the actin cytoskelton in podocytes
    Group leader: Christopher Dlugos
    Dispatching clinic: Department of Medicine D - Nephrology and Rheumatology
    Host institute: Institute of Cell Dynamics and Imaging
    Funding period: 01/2015 - 12/2017
  • SEED 05/15 - The role of GABAergic transmission and chloride homeostasis in pain development and processing
    Group leader: Tobias Schmidt
    Dispatching clinic: Department of Anaesthesiology, Intensive Care and Pain Therapy
    Host institute: Institute of Physiology I
    Funding period: 01/2015 - 12/2017
  • SEED 04/12 - The role of L-selectin topography in integrin activation and lymphocyte homing
    Group leader: Konrad-Robert Buscher
    Dispatching clinic: Department of Anaesthesiology, Intensive Care and Pain Therapy
    Host institute: Institute of Physiological Chemistry and Pathobiochemistry
    Funding period: 04/2012 - 03/2014
  • SEED 03/12 - The role of K2P-channels (TASK1-3, TRESK) for intracellular signalling pathways in T-Lymphocytes
    Group leader: Stefan Bittner
    Dispatching clinic: Division of General Neurology
    Host institute: Institute of Physiology - Neuropathophysiology
    Funding period: 01/2012 - 12/2014
  • SEED 02/12 - Functional analysis of the WWC-protein family in epithelial cell polarity
    Group leader: Dirk Oliver Wennmann
    Dispatching clinic: Department of Medicine D - Nephrology and Rheumatology
    Host institute: Institute of Medical Biochemistry (ZMBE)
    Funding period: 01/2012 - 12/2014
  • SEED 01/12 - The role of growth-differentiation factor (GDF)-15 in platelet activation, thrombus formation and platelet-mediated inflammation
    Group leader: Jan Rossaint
    Dispatching clinic: Department of Anaesthesiology, Intensive Care and Pain Therapy
    Host institute: Max Planck Institute für Molecular Biomedicine
    Funding period: 01/2012 - 12/2014