Southern Blot Analysis
We provide complete Southern blot analysis services for precise confirmation of targeted genetic modifications in ES cells and transgenic mouse lines. This classical yet powerful method allows accurate detection of integration sites, copy numbers estimation, and structural integrity of inserted DNA sequences.
Probe Design and Synthesis for Southern Blot
On request, TRAM offers custom design and synthesis of Southern blot probes as an additional service. Each probe is tailored for your specific construct or locus, ensuring optimal hybridization efficiency and high signal-to-noise ratios for clear, interpretable results.