Following my degree in biology, I pursued a PhD focusing on human stem cells at the University of California San Francisco (UCSF) and Stanford University. I joined the CeRA in 2008 to investigate the molecular makeup of the spermatogonial stem cell compartment of the testis during development and in cases of male infertility.
Our research within the CRU326 is focusing on the molecular alterations of the spermatogonial compartment in men with impaired sperm production, applying single cell RNA sequencing and quantitative marker profiling. As member of the ORCHID-NET consortium and ReproTrack.MS, we are focusing on fertility preservation measures for boys. To this end, we seek to understand the molecular and cellular changes associated with spermatogonial maturation from birth, through puberty and to the adult.
Dr. med. Jann-Frederik Cremers Assistant Medical Director Specialist for urology, andrology and tumour therapy Tel.: +49 (0)251 83 56095 E-Mail: Jann-Frederik Cremers ResearchGate
I am an urologist and andrologist and am a senior physician responsible for the surgical part of the Centre of Reproductive Medicine and Andrology. In my office hours I see patients with different andrological problems. One focus here are fertility disorders, which can have very different causes. As the responsible surgeon, I perform operations such as microsurgical testicular sperm extraction (mTESE) on patients with azoospermia. These sperm can then be used in the frame of artificial reproductive treatments. Thanks to the mTESE, many couples have the chance to fulfill their wish for parenthood. Scientifically, I am working in close collaboration with Prof. Dr. Neuhaus as I am interested in unveiling the underlying molecular mechanisms associated with impaired spermatogenesis, as this knowledge can perspectively help to improve the treatment of our patients.
Dr. med. Claudia Krallmann Assistant Medical Director Specialist for urology, andrology and general medicine Tel.: +49 (0)251 83 56095 E-Mail: Claudia Krallmann
After completing my medical studies and doctorate in Münster, I obtained my specialist qualifications in urology and general practice. I have worked at CeRA since 2006, completing further training in andrology and sexual medicine during this time and am currently a senior physician at the Department for Andrology, which sees around 4,500 patients each year with various andrological issues. I see myself as an important interface between the clinic's patients and researchers. Issues from the clinic and science can be discussed on an ongoing basis, and research approaches can be examined for their clinical relevance. This translational research approach, 'from bench to bedside and back', connects my work with the CeRA working groups and the reproductive genetics department. Priority topics include fertility protection in the pre-pubertal age group and the most severe forms of infertility.
As I was finishing my degree back in Argentina, I was determined to work on Reproduction. Due to this, I started my research path in immunology of pregnancy, transitioned to the clinics to be trained as an embryologist, and finally returned to science to pursue my PhD in Münster. During that time, I focused on understanding testis development at single-cell RNA level, using the marmoset as a model, with my main interest being spermatogonial stem cell differentiation. Now, I continue working on the same project as a Medical Scientist within ReproTrack.MS and I am a board member of the Network for Young Researchers in Andrology (NYRA).
I am working as a technician in the histology laboratory. My work in this group involves many immunohistological stainings for the Androprotect program. This also includes the analyses of the tissue samples using a quantification program and data processing. I also support the clinic with the processing of tissue samples for the fertility center.
Dr. med. Florian Schneider Specialist in Pediatrics and Adolescent Medicine, Neonatology and Diabetology Tel.: +49 (0)251 83 46031 E-Mail: Florian Schneider
