Germline variants are frequently associated with childhood cancers. The identification and interpretation of these genetic variants can therefore contribute to the understanding of these rare pediatric diseases.

In collaboration with the TUM School of Medicine and Health at the Technical University of Munich, we are investigating parent-child trio datasets from exon sequencing data using a specialized bioinformatics pipeline to identify inherited and newly emerging variants in the genomes of affected children with high accuracy and precision.
 

Contact: Dr. Carolin Walter