Latest Publications

Berres S, Gromoll J, Wöste M, Sandmann S, Laurentino S. OGRE: calculate, visualize, and analyze overlap between genomic input regions and public annotations. BMC Bioinformatics. 2023 Jul;24(1):300. doi: 10.1186/s12859-023-05422-w

Ammar OF, Sharma K, Liperis G, Fraire-Zamora JJ, Serdarogullari M, Ali ZE, Ramasamy R, Laurentino S, Watkins A, Mincheva M (2023) Balancing the scales: the interplay of diet, exercise, GLP-1 receptor agonists, and obesity in shaping male reproductive health. Hum Reprod 21:dead126. doi: 10.1093/humrep/dead126

Höffken V, Di Persio S, Laurentino S, Wyrwoll MJ, Terwort N, Hermann A, Röpke A, Oud MS, Wistuba J, Kliesch S, Pavenstädt HJ, Tüttelmann F, Neuhaus N, Kremerskothen J (2023) WWC2 expression in the testis: Implications for spermatogenesis and male fertility. FASEB J37(5):e22912. doi: 10.1096/fj.202200960R

Hiort M, Rohayem J, Knaf R, Laurentino S, Berglund A, Gravholt CH, Gromoll J, Wistuba J (2023) Testicular architecture of men with 46,XX testicular Disorders of Sex Development. Sex Dev. doi: 10.1159/000528955

Siebert-Kuss LM, Krenz H, Tekath T, Wöste M, Di Persio S, Terwort N, Wyrwoll MJ, J-F Cremers, Wistuba J, Dugas M, Kliesch S, Schlatt S, Tüttelmann F, Gromoll J, Neuhaus N, Sandra Laurentino (2022) Transcriptome analyses in infertile men reveal germ cell-specific expression and splicing patterns. Life Science Alliance 6:e202201633. DOI: 10.26508/lsa.202201633 

Patel M, Muthigi A, Laurentino S, Diaz P, Ramasamy R. Male Reproductive Aging: Can Men with Oligospermia Become Azoospermic Over Time? International Journal of Impotence Research (Epub ahead of print). DOI: 10.1038/s41443-022-00634-9 

Di Persio S, Tekath T, Siebert-Kuss LM, Cremers JF, Wistuba J, Li X, Meyer Zu Hörste G, Drexler HCA, Wyrwoll MJ, Tüttelmann F, Dugas M, Kliesch S, Schlatt S, Laurentino S, Neuhaus N (2021) Single-cell RNA-seq unravels alterations of the human spermatogonial stem cell compartment in patients with impaired spermatogenesis. Cell Reports Medicine 2:100395. DOI: 10.1016/j.xcrm.2021.100395 (shared senior authorship with N Neuhaus).

Di Persio S, Leitão E, Wöste M, Tekath T, Cremers JF, Dugas M, Li X, Zu Hörste GM, Kliesch S, Laurentino S, Neuhaus N, Horsthemke B (2021) Whole-genome methylation analysis of testicular germ cells from cryptozoospermic men points to recurrent and functionally relevant DNA methylation changes. Clinical Epigenetics 13:160. DOI: 10.1186/s13148-021-01144-z

Pohl E, Gromoll J, Wistuba J, Laurentino S (2021) Healthy ageing and spermatogenesis. Reproduction. 161:R89. DOI: 10.1530/REP-20-0633

Rohayem J, Zitzmann M, Laurentino S, Kliesch S, Nieschlag E, Holterhus P-M, Kulle A (2021) The role of gonadotropins in testicular and adrenal androgen biosynthesis pathways -insights from males with congenital hypogonadotropic hypogonadism on hCG/rFSH and on testosterone replacement.  Clinical Endocrinology 94:90. DOI: 10.1111/cen.14324