Infertility is a common condition and clinical causes are equally prevalent in both men and women. However, the underlying mechanisms of infertility remain largely unclear, often impeding specific diagnoses and personalised, evidence-based treatments. 

Reproduction.MS coordinates a dynamic network of interdisciplinary collaborative research funded by the DFG, BMBF, and internal sources, bridging the gap between science and clinic. 

The DFG CRC initiative 'Reproduction.MS' will expand and enhance ongoing efforts to establish a beacon of excellence in deciphering the molecular mechanisms of male infertility. By utilising innovative research approaches und cutting-edge technologies, the initiative aims to generate new insights and therapeutic approaches.

The BMFTR-funded Junior Scientist Research Centre 'ReproTrack.MS' offers ten postdoctoral reproductive medical and clinician scientists a structured programme to advance their academic careers. Working at the interface of basic and clinical research in Münster, it provides networking and collaboration to drive translational reproductive research. 

The 'ProCon.MS' study develops novel tools for early diagnosing male infertility and developing non-hormonal female contraceptives. Central to the project are large-scale direct comparisons of sperm function in infertile and fertile men. The study is conducted with partners at the Universities of Birmingham and Dundee, funded by the Gates Foundation.

The DFG Clinical Research Unit 'Male Germ Cells', investigates the genetic and epigenetic causes of male infertility and the molecular mechanisms essential for germ cell function. Using advanced technologies and cross-project biobanks and databases, it examines the regulation of sperm production to identify infertility causes and inform diagnosis and treatment.

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