The research at the Institute of Cell Biology is aimed at understanding the control over cell differentiation, cell proliferation, cell fate maintenance, cell migration, and the dynamics and organisation of the cytoskeleton in cell and tissue morphogenesis. These biological processes are at the basis of inflammation, the cellular response to infection and tumour metastasis, events that involve the mobilisation of immune and cancer cells.

We explore those topics employing new optical and chemical tools in conjunction with classical genetic approaches, with advanced image acquisition and processing procedures used for evaluation of the results. The biological models we use include primordial germ cells in zebrafish (D. rerio) embryos (Raz group), developing tissues and organs in the fruit fly (D. melanogaster) (Matis group), with relevant mechanical properties of active and passive cellular systems explored in cell culture and in zebrafish embryos (Betz group).

Institute Retreat 2019

Funding our work