Experimental Animal StudiesThe aim of the experimental animal studies is to identify crucial mechanisms of the interplay between genetic, environmental and neurobiological systems, which form the basis of anxiety traits, thereby providing a reasonable basis for explanation of data from and providing input into complementary human studies.

Research Projects

A01	Life history, serotonin transporter genotype and anxiety-like behaviour: testing the “coping-with-challenge hypothesis”	Sachser, Richter, Lesch,
A02	Contribution of CRF and 5-HT in the anterodorsal BNST to phasic and sustained fear in freely behaving mice	Seidenbecher
A03	Distinct circuits of the extended amygdala regulating fear generalization and extinction	Pape
A04	Cell type-specificity of endocannabinoid signaling in amygdala-BNST projections regulating sustained fear	Lutz, Pape
A05	Stress-induced programming in serotonin (5-HT) system-modified mice: epigenetic editing as a strategy to cope with anxiety	van den Hove, Lesch, Schmitt-Böhrer
A08	Impact of the Neuropeptide S system and NPS-receptor polymorphisms on fear and anxiety	Jüngling
A10	Role of hippocampal BDNF signaling in contextual fear learning, fear generalization and context discrimination	Blum, Sendtner