Gene-environment interactions, neural circuits and generalization in dimensional
endophenotypes of fear and anxiety in adults and children:
development and reversibility

Domschke, Lueken, Dannlowski, Lonsdorf, Romanos, Pauli, Deckert

The Z02 project serves as a central recruitment project (1,500 adults and 500 children) for projects in areas B and C. Probands are furthermore included in a psychophysiological fear generalization and discrimination learning study to identify the influences of psychological, genetic and epigenetic factors on both developmental and reversibility aspects of conditioned and generalized fear.

Publications

Gottschalk MG, Domschke K (2018)

Genetische Aspekte in der Ätiologie und Therapie von Angsterkrankungen, in: Angst: Medizin. Psychologie. Gesellschaft., Hrsg.: Zwanzger P, Medizinisch Wissenschaftliche Verlagsgesellschaft, Berlin, 2018, ISBN 978-3954664061