Gene-environment interactions, neural circuits and generalization in dimensional
endophenotypes of fear and anxiety in adults and children:
development and reversibility
Domschke, Lueken, Dannlowski, Lonsdorf, Romanos, Pauli, Deckert
The Z02 project serves as a central recruitment project (1,500 adults and 500 children) for projects in areas B and C. Probands are furthermore included in a psychophysiological fear generalization and discrimination learning study to identify the influences of psychological, genetic and epigenetic factors on both developmental and reversibility aspects of conditioned and generalized fear.