Dr. rer. nat. Birgit Stallmeyer


Gruppenleitung | Laborleitung
Tel.: +49 (251) 83 - 53234
E-Mail: Birgit Stallmeyer
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  • Wissenschaftlicher Werdegang

    2022 – Gruppenleiterin am Institut für Reproduktionsgenetik (IRG), Universität Münster
    2021 – Leitende Wissenschaftlerin am Institut für Reproduktionsgenetik (IRG), Universität Münster
    2021 – Gleichstellungsbeauftragte der Klinischen Forschungsgruppe CRU326 ‘Male Germ Cells’
    2007 – 2021 Leitende Wissenschaftlerin am Institut für Genetik von Herzerkrankungen (IfGH), UKM
    2012 – 2016 Stellvertretende Qualitätsmanagementbeauftragte (DIN ISO 15189:2014) am Institut für Genetik von Herzkrankheiten (IfGH), UKM
    2001 – 2003 Postdoktorandin am Leibniz-Institut für Arterioskleroseforschung, Münster
    1998 – 2000 Postdoktorandin am Institut für Pharmakologie und Toxikologie des Universitätsklinikums Frankfurt am Main
    1998 Verleihung des Doktorgrades (Dr. rer. nat.), Note: Summa cum laude; Thema: Identifizierung und funktionelle Charakterisierung humaner cDNA Klone, die für Proteine der Molybdäncofaktor-Synthese codieren und Nachweis einer Molybdäncofaktor-Synthesefunktion für das Neuroprotein Gephyrin
    1994 – 1998 Doktorandin am Institut für Botanik, Technische Universität Braunschweig
    1994 Diplom in Biologie; Thema der Diplomarbeit: Isolierung und funktionelle Charakterisierung einer cDNA aus A.thaliana, die die E.coli Mutante mogA funktionell komplementiert
    1990 – 1994 Biologiestudium, Technische Universität Braunschweig
    1988 – 1990 Biologiestudium, Universität Münster

  • Ausgewählte Publikationen

    1. Dicke A-K, Albrethsen J, Hoare BL, Wyrwoll MJ, Busch AS, Fietz D, Pilatz A, Bühlmann C, Juul A, Kliesch S, Gromoll J, Bathgate RAD, Tüttelmann F*, Stallmeyer B*. Bi-allelic variants in INSL3 and RXFP2 cause bilateral cryptorchidism and male infertility. Hum Reprod. 38:1412-1423, 2023.
    2. Dicke AK, Pilatz A, Wyrwoll MJ, Punab M, Ruckert C, Nagirnaja L, Aston KI, Conrad DF, Di Persio S, Neuhaus N, Fietz D, Laan M, Stallmeyer B*, Tüttelmann F*. DDX3Y is likely the key spermatogenic factor in the AZFa region that contributes to human non-obstructive azoospermia. Commun Biol. 6(1): 350, 2023.
    3. Rinné S*, Stallmeyer B*, Pinggera A, Netter MF, Matschke LA, Dittmann S, Kirchhefer U, Neudorf U, Opp J, Striessnig J, Decher N, Schulze-Bahr E. Whole Exome Sequencing Identifies a Heterozygous Variant in the Cav1.3 Gene CACNA1D Associated with Familial Sinus Node Dysfunction and Focal Idiopathic Epilepsy. Int J Mol Sci. 23(22): 14215, 2022.
    4. Kuß J*, Stallmeyer B*, Goldstein M, Rinné S, Pees C, Zumhagen S, Seebohm G, Decher N, Pott L, Kienitz MC, Schulze-Bahr E. Familial Sinus Node Disease Caused by a Gain of GIRK (G-Protein Activated Inwardly Rectifying K+ Channel) Channel Function. Circ Genom Precis Med. 12(1): e002238, 2019.
    5. Stallmeyer B, Dittmann S, Schulze-Bahr E. Genetic testing to prevent sudden cardiac death. Internist. 59(8): 776-789, 2018.
    6. Stallmeyer B*, Kuss J*, Kotthoff S, Zumhagen S, Vowinkel K, Rinne S, Matschke LA, Friedrich C, Schulze-Bahr E, Rust S, Seebohm G, Decher N, Schulze-Bahr E. A Mutation in the G-Protein Gene GNB2 Causes Familial Sinus Node and Atrioventricular Conduction Dysfunction. Circ Res. 120: e33-e44, 2018.
    7. Stallmeyer B, Dittmann S, Seebohm G, Muller J, Schulze-Bahr E. Molecular genetic diagnostics for ventricular arrhythmias and sudden cardiac death syndromes. Herz. 42: 476-484, 2017.
    8. Stallmeyer B, Schulze-Bahr E. Cardiovascular disease and sudden cardiac death: between genetics and genomics. Eur Heart J. 36: 1643-5, 2015.
    9. Stallmeyer B, Zumhagen S, Denjoy I, Duthoit G, Hebert JL, Ferrer X, Maugenre S, Schmitz W, Kirchhefer U, Schulze-Bahr E, Guicheney P, Schulze-Bahr E. Mutational spectrum in the Ca(2+)-activated cation channel gene TRPM4 in patients with cardiac conductance disturbances. Hum Mutat. 33: 109-17, 2012.
    10. Stallmeyer B, Koopmann M, Schulze-Bahr E. Identification of novel mutations in LMNA associated with familial forms of dilated cardiomyopathy. Genet Test Mol Biomarkers. 16: 543-9, 2012.
    11. Stallmeyer B, Fenge H, Nowak-Gottl U, Schulze-Bahr E. Mutational spectrum in the cardiac transcription factor gene NKX2.5 (CSX) associated with congenital heart disease. Clinical Genetics. 78: 533-40, 2010.
    12. Skaletz-Rorowski A, Eschert H, Leng J, Stallmeyer B, Sindermann JR, Pulawski E, Breithardt G. PKC delta-induced activation of MAPK pathway is required for bFGF-stimulated proliferation of coronary smooth muscle cells. Cardiovascular Research. 67: 142-50, 2005.
    13. Stallmeyer B, Anhold M, Wetzler C, Kahlina K, Pfeilschifter J, Frank S. Regulation of eNOS in normal and diabetes-impaired skin repair: implications for tissue regeneration. Nitric oxide : biology and chemistry. 6: 168-77, 2002.
    14. Stallmeyer B, Pfeilschifter J, Frank S. Systemically and topically supplemented leptin fails to reconstitute a normal angiogenic response during skin repair in diabetic ob/ob mice. Diabetologia. 44: 471-9, 2001.
    15. Stallmeyer B, Kampfer H, Podda M, Kaufmann R, Pfeilschifter J, Frank S. A novel keratinocyte mitogen: regulation of leptin and its functional receptor in skin repair. The Journal of Investigative Dermatology. 117: 98-105, 2001.
    16. Frank S*, Stallmeyer B*, Kampfer H, Kolb N, Pfeilschifter J. Leptin enhances wound re-epithelialization and constitutes a direct function of leptin in skin repair. The Journal of clinical investigation. 106: 501-9, 2000.
    17. Stallmeyer B, Schwarz G, Schulze J, Nerlich A, Reiss J, Kirsch J, Mendel RR. The neurotransmitter receptor-anchoring protein gephyrin reconstitutes molybdenum cofactor biosynthesis in bacteria, plants, and mammalian cells. Proc Natl Acad Sci U S A. 96: 1333-8, 1999.
    18. Stallmeyer B, Kampfer H, Kolb N, Pfeilschifter J, Frank S. The function of nitric oxide in wound repair: inhibition of inducible nitric oxide-synthase severely impairs wound reepithelialization. The Journal of investigative dermatology. 113: 1090-8, 1999.
    19. Stallmeyer B, Drugeon G, Reiss J, Haenni AL, Mendel RR. Human molybdopterin synthase gene: identification of a bicistronic transcript with overlapping reading frames. American Journal of Human Genetics. 64: 698-705, 1999.
    20. Frank S*, Stallmeyer B*, Kampfer H, Kolb N, Pfeilschifter J. Nitric oxide triggers enhanced induction of vascular endothelial growth factor expression in cultured keratinocytes (HaCaT) and during cutaneous wound repair. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 13: 2002-14, 1999.
    21. Stallmeyer B, Nerlich A, Schiemann J, Brinkmann H, Mendel RR. Molybdenum co-factor biosynthesis: the Arabidopsis thaliana cDNA cnx1 encodes a multifunctional two-domain protein homologous to a mammalian neuroprotein, the insect protein Cinnamon and three Escherichia coli proteins. The Plant journal : for cell and molecular biology. 8: 751-62, 1995.

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