Ten pilot projects granted by the Clinical Research Unit 326
The CRU326 offered the opportunity to apply for a start-up funding for own research projects. Overall, 10 applications were granted.
The funding received six members from CRU labs. In addition, six external teams with CRU-affiliated topics were supported:
'Genetic screen in Drosophila melanogaster - deciphering the importance of motile cilia for male infertility'
'CASA 2.0 – A new approach towards early diagnosis of hitherto unexplained male infertility'
'Genomic elucidation of clonal expansion in the human male germline'
'Analysis of the assembly and composition of the CatSper-channel complex in human sperm by comparative quantitative proteomics'
Prof. Dr. Erich Bornberg-Bauer, Institute of Evolution and Biodiversity, FB 13, external
'Sperm Malfunctioning in Humans as a Collateral Damage of Evolutionary Constraints'
Priv.-Doz. Dr. rer. nat. Verena Nordhoff, Centre of Reproductive Medicine and Andrology, Dr. rer. nat. Julia Floehr, RWTH Aachen, Dr. rer. nat. Susanne Ledig, Insitute of Human Genetics, and Univ.-Prof. Dr. med. Hermann M. Behre, UKM-Kinderwunschzentrum, external
'Male and female reproductive health - unravelling genetic causes for failed sperm-egg interaction in cases of In-vitro Fertilisation (IVF) failure'
PD Dr. Kornelius Kerl, Pediatric Hematology and Oncology, external
'Primordial Germ Cells as the cellular origin of atypical teratoid rhabdoid tumors of the MYC subgroup – in vivo evidence using genetically engineered mouse models'
Dr. rer. nat. Gerard W. Dougherty, General Pediatrics, AG Omran, external
'A Proteomic Survey of AMP-binding Proteins in Mammalian Sperm to Facilitate Genetic Diagnosis of Male Infertility'
Univ.-Prof. Dr. rer. nat. Johannes A. Eble, Institute of Physiological Chemistry and Pathobiochemistry, external
'Extracellular matrix components and integrin-mediated contacts as determinants of fate and function of Sertoli cells'
Prof. Dr. Martin Götte, Clinic for Gynecology and Obstetrics, external
'A human organoid model of endometrial receptivity'