1. Wieder T, Essmann F, Prokop A, Schmelz K, Schulze-Osthoff K, Beyaert R, Dorken B, Daniel PT. Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3. Blood.97:1378-1387 (2001)
2. Wieder T, Prokop A, Bagci B, Essmann F, Bernicke D, Schulze-Osthoff K, Dorken B, Schmalz HG, Daniel PT, Henze G. Piceatannol, a hydroxylated analog of the chemopreventive agent resveratrol, is a potent inducer of apoptosis in the lymphoma cell line BJAB and in primary, leukemic lymphoblasts. Leukemia.15:1735-1742 (2001)
3. Totzke G, Bruning T, Vetter H, Schulze-Osthoff K, Ko Y. p53 Downregulation in myelodysplastic syndrome - a quantitative analysis by competitive RT-PCR. Leukemia.15:1663-1664 (2001)
4. Thorey IS, Roth J, Regenbogen J, Halle JP, Bittner M, Vogl T, Kaesler S, Bugnon P, Reitmaier B, Durka S, Graf A, Wockner M, Rieger N, Konstantinow A, Wolf E, Goppelt A, Werner S. The Ca2+-binding proteins S100A8 and S100A9 are encoded by novel injury-regulated genes. Journal of Biological Chemistry.276:35818-35825 (2001)
5. Sunderkotter C, Seeliger S, Schonlau F, Roth J, Hallmann R, Luger TA, Sorg C, Kolde G. Different pathways leading to cutaneous leukocytoclastic vasculitis in mice. Experimental Dermatology.10:391-404 (2001)
6. Stepczynska A, Lauber K, Engels IH, Janssen O, Kabelitz D, Wesselborg S, Schulze-Osthoff K. Staurosporine and conventional anticancer drugs induce overlapping, yet distinct pathways of apoptosis and caspase activation. Oncogene.20:1193-1202 (2001)
7. Schmidt M, Lugering N, Lugering A, Pauels HG, Schulze-Osthoff K, Domschke W, Kucharzik T. Role of the CD95/CD95 ligand system in glucocorticoid-induced monocyte apoptosis. Journal of Immunology.166:1344-1351 (2001)
8. Rudner J, Lepple-Wienhues A, Budach W, Berschauer J, Friedrich B, Wesselborg S, Schulze-Osthoff K, Belka C. Wild-type, mitochondrial and ER-restricted Bcl-2 inhibit DNA damage-induced apoptosis but do not affect death receptor-induced apoptosis. Journal of Cell Science.114:4161-4172 (2001)
9. Roth J, Goebeler M, Sorg C. S100A8 and S100A9 in inflammatory diseases. Lancet.357:1041-1041 (2001)
10. Roth J, Goebeler M, Ludwig S, Wagner L, Kilian K, Sorg C, Harms E, Schulze-Osthoff K, Koch HG. Homocysteine inhibits tumor necrosis factor-induced activation of endothelium via modulation of nuclear factor-kappa b activity. Biochimica Et Biophysica Acta-Molecular Cell Research.1540:154-165 (2001)
11. Renz A, Berdel WE, Kreuter M, Belka C, Schulze-Osthoff K, Los M. Rapid extracellular release of cytochrome c is specific for apoptosis and marks cell death in vivo. Blood.98:1542-1548 (2001)
12. Renz A, Burek C, Mier W, Mozoluk M, Schulze-Osthoff K, Los M. Cytochrome c is rapidly extruded from apoptotic cells and detectable in serum of anticancer-drug treated tumor patients. Progress in Basic and Clinical Immunology. Vol. 495. Advances in Experimental Medicine and Biology; 2001:331-334
13. Nacken W, Lekstrom-Himes JA, Sorg C, Manitz MP. Molecular analysis of the mouse S100A9 gene and evidence that the myeloid specific transcription factor C/EBPepsilon is not required for the regulation of the S100A9/A8 gene expression in neutrophils. Journal of Cellular Biochemistry.80:606-616 (2001)
14. Luetjens CM, Kogel D, Reimertz C, Dussmann H, Renz A, Schulze-Osthoff K, Nieminen AL, Poppe M, Prehn JHM. Multiple kinetics of mitochondrial cytochrome c release in drug-induced apoptosis. Molecular Pharmacology.60:1008-1019 (2001)
15. Los M, Stroh C, Janicke RU, Engels IH, Schulze-Osthoff K. Caspases: more than just killers? Trends in Immunology.22:31-34 (2001)
16. Lauber K, Appel HAE, Schlosser SF, Gregor M, Schulze-Osthoff K, Wesselborg S. The adapter protein apoptotic protease-activating factor-1 (Apaf-1) is proteolytically processed during apoptosis. Journal of Biological Chemistry.276:29772-29781 (2001)
17. Konig S, Zeller M, Peter-Katalinic J, Roth J, Sorg C, Vogl T. Use of nonspecific cleavage products for protein sequence analysis as shown on calcyclin isolated from human granulocytes. Journal of the American Society for Mass Spectrometry.12:1180-1185 (2001)
18. Kerkhoff C, Sorg C, Tandon NN, Nacken W. Interaction of S100A8/S100A9 - Arachidonic acid complexes with the scavenger receptor CD36 may facilitate fatty acid uptake by endothelial cells. Biochemistry.40:241-248 (2001)
19. Kauschke E, Komiyama K, Moro I, Eue I, Konig S, Cooper EL. Evidence for perforin-like activity associated with earthworm leukocytes. Zoology-Analysis of Complex Systems.104:13-24 (2001)
20. Janicke RU, Engels IH, Dunkern T, Kaina B, Schulze-Osthoff K, Porter AG. Ionizing radiation but not anticancer drugs causes cell cycle arrest and failure to activate the mitochondrial death pathway in MCF-7 breast carcinoma cells. Oncogene.20:5043-5053 (2001)
21. Hogger P, Sorg C. Soluble CD163 inhibits phorbol ester-induced lymphocyte proliferation. Biochemical and Biophysical Research Communications.288:841-843 (2001)
22. Held J, Schulze-Osthoff K. Potential and caveats of TRAIL in cancer therapy. Drug Resistance Updates.4:243-252 (2001)
23. Heiduschka P, Romann I, Ecken H, Schoning M, Schuhmann W, Thanos S. Defined adhesion and growth of neurones on artificial structured substrates. Electrochimica Acta.47:299-307 (2001)
24. Hashemi FB, Mollenhauer U, Madsen LD, Sha BE, Nacken W, Moyer MB, Sorg C, Spear GT. Myeloid-related protein (MRP)-8 from cervico-vaginal secretions activates HIV replication. Aids.15:441-449 (2001)
25. Friedrich K, Wieder T, Von Haefen C, Radetzki S, Janicke R, Schulze-Osthoff K, Dorken B, Daniel PT. Overexpression of caspase-3 restores sensitivity for drug-induced apoptosis in breast cancer cell lines with acquired drug resistance. Oncogene.20:2749-2760 (2001)
26. Ferrari D, Stroh C, Wesselborg S, Di Virgilio F, Schulze-Osthoff K. Extracellular ATP activates transcription factor NFAT in mouse microglial cells. Drug Development Research.52:213-219 (2001)
27. Eue I, Sorg C. Arachidonic acid specifically regulates binding of S100A8/A9, a heterodimer complex of the S100 class of calcium binding proteins, to human microvascular endothelial cells. Atherosclerosis.154:505-508 (2001)
28. Eue I. Growth inhibition of human mammary carcinoma by liposomal hexadecylphosphocholine: Participation of activated macrophages in the antitumor mechanism. International Journal of Cancer.92:426-433 (2001)
29. Daniel PT, Wieder T, Sturm I, Schulze-Osthoff K. The kiss of death: promises and failures of death receptors and ligands in cancer therapy. Leukemia.15:1022-1032 (2001)
30. Clauss M, Sunderkotter C, Sveinbjornsson B, Hippenstiel S, Willuweit A, Marino M, Haas E, Seljelid R, Scheurich P, Suttorp N, Grell M, Risau W. A permissive role for tumor necrosis factor in vascular endothelial growth factor-induced vascular permeability. Blood.97:1321-1329 (2001)
31. Burek C, Roth J, Koch HG, Harzer K, Los M, Schulze-Osthoff K. The role of ceramide in receptor- and stress-induced apoptosis studied in acidic ceramidase-deficient Farber disease cells. Oncogene.20:6493-6502 (2001)
32. Brehm BR, Bock C, Wesselborg S, Pfeiffer S, Schuler S, Schulz-Osthoff K. Prevention of human smooth muscle cell proliferation without induction of apoptosis by the topoisomerase I inhibitor topotecan. Biochemical Pharmacology.61:119-127 (2001)
33. Brehm BR, Wolf SC, Bertsch D, Klaussner M, Wesselborg S, Schuler S, Schulze-Osthoff K. Effects of nebivolol on proliferation and apoptosis of human coronary artery smooth muscle and endothelial cells. Cardiovascular Research.49:430-439 (2001)
34. Berg CP, Engels IH, Rothbart A, Lauber K, Renz A, Schlosser SF, Schulze-Osthoff K, Wesselborg S. Human mature red blood cells express caspase-3 and caspase-8, but are devoid of mitochondrial regulators of apoptosis. Cell Death and Differentiation.8:1197-1206 (2001)
35. Belka C, Schmid B, Marini P, Durand E, Rudner J, Faltin H, Bamberg M, Schulze-Osthoff K, Budach W. Sensitization of resistant lymphoma cells to irradiation-induced apoptosis by the death ligand TRAIL. Oncogene.20:2190-2196 (2001)
36. Bantel H, Ruck P, Gregor M, Schulze-Osthoff K. Detection of elevated caspase activation and early apoptosis in liver diseases. European Journal of Cell Biology.80:230-239 (2001)
37. Bantel H, Lugering A, Poremba C, Lugering N, Held J, Domschke W, Schulze-Osthoff K. Caspase activation correlates with the degree of inflammatory liver injury in chronic hepatitis C virus infection. Hepatology.34:758-767 (2001)
38. Bantel H, Sinha B, Domschke W, Peters G, Schulze-Osthoff K, Janicke RU. alpha-toxin is a mediator of Staphylococcus aureus-induced cell death and activates caspases via the intrinsic death pathway independently of death receptor signaling. Journal of Cell Biology.155:637-647 (2001)