1. Achouiti A, Vogl T, Van der Meer AJ, Stroo I, Florquin S, de Boer OJ, Roth J, Zeerleder S, van 't Veer C, de Vos AF, van der Poll T. Myeloid-related protein-14 deficiency promotes inflammation in staphylococcal pneumonia.
European Respiratory Journal 46:464-473.2015.
2. Anink J, Van Suijlekom-Smit LWA, Otten MH, Prince FHM, van Rossum MAJ, Dolman KM, Hoppenreijs EPAH, ten Cate R, Ursu S, Wedderburn LR, Horneff G, Frosch M, Vogl T, Gohar F, Foell D, Roth J, Holzinger D. MRP8/14 serum levels as a predictor of response to starting and stopping anti-TNF treatment in juvenile idiopathic arthritis.
Arthritis Research & Therapy 17.2015.
3. Becker A, Hokamp NG, Zenker S, Flores-Borja F, Barzcyk K, Varga G, Roth J, Geyer C, Heindel W, Bremer C, Vogl T, Eisenblaetter M. Optical In Vivo Imaging of the Alarmin S100A9 in Tumor Lesions Allows for Estimation of the Individual Malignant Potential by Evaluation of Tumor-Host Cell Interaction.
Journal of Nuclear Medicine 56:450-456.2015.
4. Chernov AV, Dolkas J, Hoang K, Angert M, Srikrishna G, Vogl T, Baranovskaya S, Strongin AY, Shubayev VI. The Calcium-binding Proteins S100A8 and S100A9 Initiate the Early Inflammatory Program in Injured Peripheral Nerves.
Journal of Biological Chemistry 290:11771-11784.2015.
5. Cho H, Jeong D-W, Liu Q, Yeo W-S, Vogl T, Skaar EP, Chazin WJ, Bae T. Calprotectin Increases the Activity of the SaeRS Two Component System and Murine Mortality during Staphylococcus aureus Infections.
Plos Pathogens 11.2015.
6. Choi IY, Gerlag DM, Herenius MJ, Thurlings RM, Wijbrandts CA, Foell D, Vogl T, Roth J, Tak PP, Holzinger D. MRP8/14 serum levels as a strong predictor of response to biological treatments in patients with rheumatoid arthritis.
Annals of the Rheumatic Diseases 74:499-505.2015.
7. Daebritz J, Weinhage T, Varga G, Wirth T, Walscheid K, Brockhausen A, Schwarzmaier D, Brueckner M, Ross M, Bettenworth D, Roth J, Ehrchen JM, Foell D. Reprogramming of Monocytes by GM-CSF Contributes to Regulatory Immune Functions during Intestinal Inflammation.
Journal of Immunology 194:2424-2438.2015.
8. De Jong HK, Achouiti A, Koh GCKW, Parry CM, Baker S, Abul Faiz M, van Dissel JT, Vollaard AM, van Leeuwen EMM, Roelofs JJTH, de Vos AF, Roth J, van der Poll T, Vogl T, Wiersinga WJ. Expression and Function of S100A8/A9 (Calprotectin) in Human Typhoid Fever and the Murine Salmonella Model.
Plos Neglected Tropical Diseases 9.2015.
9. Dessing MC, Tammaro A, Pulskens WP, Teske GJ, Butter LM, Claessen N, van Eijk M, van der Poll T, Vogl T, Roth J, Florquin S, Leemans JC. The calcium-binding protein complex S100A8/A9 has a crucial role in controlling macrophage-mediated renal repair following ischemia/reperfusion.
Kidney International 87:85-94.2015.
10. Fassl SK, Austermann J, Papantonopoulou O, Riemenschneider M, Xue J, Bertheloot D, Freise N, Spiekermann C, Witten A, Viemann D, Kirschnek S, Stoll M, Latz E, Schultze JL, Roth J, Vogl T. Transcriptome Assessment Reveals a Dominant Role for TLR4 in the Activation of Human Monocytes by the Alarmin MRP8.
Journal of Immunology 194:575-583.2015.
11. Faust A, Voeller T, Busch F, Schaefers M, Roth J, Hermann S, Vogl T. Development and evaluation of a non-peptidic ligand for the molecular imaging of inflammatory processes using S100A9 (MRP14) as a novel target.
Chemical Communications 51:15637-15640.2015.
12. Holzinger D, Fassl SK, de Jager W, Lohse P, Roehrig UF, Gattorno M, Omenetti A, Chiesa S, Schena F, Austermann J, Vogl T, Kuhns DB, Holland SM, Rodriguez-Gallego C, Lopez-Almaraz R, Arostegui JI, Colino E, Roldan R, Fessatou S, Isidor B, Poignant S, Ito K, Epple H-J, Bernstein JA, Jeng M, Frankovich J, Lionetti G, Church JA, Ong PY, LaPlant M, Abinun M, Skinner R, Bigley V, Sachs UJ, Hinze C, Hoppenreijs E, Ehrchen J, Foell D, Chae JJ, Ombrello A, Aksentijevich I, Sunderkoetter C, Roth J. Single amino acid charge switch defines clinically distinct proline-serine-threonine phosphatase-interacting protein 1 (PSTPIP1)-associated inflammatory diseases.
Journal of Allergy and Clinical Immunology 136:1337-1345.2015.
13. Pruenster M, Kurz ARM, Chung K-J, Cao-Ehlker X, Bieber S, Nussbaum CF, Bierschenk S, Eggersmann TK, Rohwedder I, Heinig K, Immler R, Moser M, Koedel U, Gran S, McEver RP, Vestweber D, Verschoor A, Leanderson T, Chavakis T, Roth J, Vogl T, Sperandio M. Extracellular MRP8/14 is a regulator of beta 2 integrin-dependent neutrophil slow rolling and adhesion.
Nat Commun 6.2015.
14. Schelbergen RF, Geven EJ, van den Bosch MHJ, Eriksson H, Leanderson T, Vogl T, Roth J, van de Loo FAJ, Koenders MI, van der Kraan PM, van den Berg WB, Blom AB, van Lent PLEM. Prophylactic treatment with S100A9 inhibitor paquinimod reduces pathology in experimental collagenase-induced osteoarthritis.
Annals of the Rheumatic Diseases 74:2254-2258.2015.
15. Schelbergen RFP, de Munter W, van den Bosch MHJ, Lafeber FPJG, Sloetjes A, Vogl T, Roth J, van den Berg WB, van der Kraan PM, Blom AB, van Lent PLEM. Alarmins S100A8/S100A9 aggravate osteophyte formation in experimental osteoarthritis and predict osteophyte progression in early human symptomatic osteoarthritis.
Annals of the Rheumatic Diseases 75:218-225.2016.
16. Van Crombruggen K, Vogl T, Perez-Novo C, Holtappels G, Bachert C. Differential release and deposition of S100A8/A9 proteins in inflamed upper airway tissue.
European Respiratory Journal 47:264-274.2016.
17. Verjans E, Ohl K, Reiss LK, van Wijk F, Toncheva AA, Wiener A, Yu Y, Rieg AD, Gaertner VD, Roth J, Knol E, Kabesch M, Wagner N, Uhlig S, Martin C, Tenbrock K. The cAMP response element modulator (CREM) regulates T(H)2 mediated inflammation.
Oncotarget 6:38538-38551.2015.
18. Wache C, Klein M, Ostergaard C, Angele B, Haecker H, Pfister H-W, Pruenster M, Sperandio M, Leanderson T, Roth J, Vogl T, Koedel U. Myeloid-Related Protein 14 Promotes Inflammation and Injury in Meningitis.
Journal of Infectious Diseases 212:247-257.2015.
European Respiratory Journal 46:464-473.2015.
2. Anink J, Van Suijlekom-Smit LWA, Otten MH, Prince FHM, van Rossum MAJ, Dolman KM, Hoppenreijs EPAH, ten Cate R, Ursu S, Wedderburn LR, Horneff G, Frosch M, Vogl T, Gohar F, Foell D, Roth J, Holzinger D. MRP8/14 serum levels as a predictor of response to starting and stopping anti-TNF treatment in juvenile idiopathic arthritis.
Arthritis Research & Therapy 17.2015.
3. Becker A, Hokamp NG, Zenker S, Flores-Borja F, Barzcyk K, Varga G, Roth J, Geyer C, Heindel W, Bremer C, Vogl T, Eisenblaetter M. Optical In Vivo Imaging of the Alarmin S100A9 in Tumor Lesions Allows for Estimation of the Individual Malignant Potential by Evaluation of Tumor-Host Cell Interaction.
Journal of Nuclear Medicine 56:450-456.2015.
4. Chernov AV, Dolkas J, Hoang K, Angert M, Srikrishna G, Vogl T, Baranovskaya S, Strongin AY, Shubayev VI. The Calcium-binding Proteins S100A8 and S100A9 Initiate the Early Inflammatory Program in Injured Peripheral Nerves.
Journal of Biological Chemistry 290:11771-11784.2015.
5. Cho H, Jeong D-W, Liu Q, Yeo W-S, Vogl T, Skaar EP, Chazin WJ, Bae T. Calprotectin Increases the Activity of the SaeRS Two Component System and Murine Mortality during Staphylococcus aureus Infections.
Plos Pathogens 11.2015.
6. Choi IY, Gerlag DM, Herenius MJ, Thurlings RM, Wijbrandts CA, Foell D, Vogl T, Roth J, Tak PP, Holzinger D. MRP8/14 serum levels as a strong predictor of response to biological treatments in patients with rheumatoid arthritis.
Annals of the Rheumatic Diseases 74:499-505.2015.
7. Daebritz J, Weinhage T, Varga G, Wirth T, Walscheid K, Brockhausen A, Schwarzmaier D, Brueckner M, Ross M, Bettenworth D, Roth J, Ehrchen JM, Foell D. Reprogramming of Monocytes by GM-CSF Contributes to Regulatory Immune Functions during Intestinal Inflammation.
Journal of Immunology 194:2424-2438.2015.
8. De Jong HK, Achouiti A, Koh GCKW, Parry CM, Baker S, Abul Faiz M, van Dissel JT, Vollaard AM, van Leeuwen EMM, Roelofs JJTH, de Vos AF, Roth J, van der Poll T, Vogl T, Wiersinga WJ. Expression and Function of S100A8/A9 (Calprotectin) in Human Typhoid Fever and the Murine Salmonella Model.
Plos Neglected Tropical Diseases 9.2015.
9. Dessing MC, Tammaro A, Pulskens WP, Teske GJ, Butter LM, Claessen N, van Eijk M, van der Poll T, Vogl T, Roth J, Florquin S, Leemans JC. The calcium-binding protein complex S100A8/A9 has a crucial role in controlling macrophage-mediated renal repair following ischemia/reperfusion.
Kidney International 87:85-94.2015.
10. Fassl SK, Austermann J, Papantonopoulou O, Riemenschneider M, Xue J, Bertheloot D, Freise N, Spiekermann C, Witten A, Viemann D, Kirschnek S, Stoll M, Latz E, Schultze JL, Roth J, Vogl T. Transcriptome Assessment Reveals a Dominant Role for TLR4 in the Activation of Human Monocytes by the Alarmin MRP8.
Journal of Immunology 194:575-583.2015.
11. Faust A, Voeller T, Busch F, Schaefers M, Roth J, Hermann S, Vogl T. Development and evaluation of a non-peptidic ligand for the molecular imaging of inflammatory processes using S100A9 (MRP14) as a novel target.
Chemical Communications 51:15637-15640.2015.
12. Holzinger D, Fassl SK, de Jager W, Lohse P, Roehrig UF, Gattorno M, Omenetti A, Chiesa S, Schena F, Austermann J, Vogl T, Kuhns DB, Holland SM, Rodriguez-Gallego C, Lopez-Almaraz R, Arostegui JI, Colino E, Roldan R, Fessatou S, Isidor B, Poignant S, Ito K, Epple H-J, Bernstein JA, Jeng M, Frankovich J, Lionetti G, Church JA, Ong PY, LaPlant M, Abinun M, Skinner R, Bigley V, Sachs UJ, Hinze C, Hoppenreijs E, Ehrchen J, Foell D, Chae JJ, Ombrello A, Aksentijevich I, Sunderkoetter C, Roth J. Single amino acid charge switch defines clinically distinct proline-serine-threonine phosphatase-interacting protein 1 (PSTPIP1)-associated inflammatory diseases.
Journal of Allergy and Clinical Immunology 136:1337-1345.2015.
13. Pruenster M, Kurz ARM, Chung K-J, Cao-Ehlker X, Bieber S, Nussbaum CF, Bierschenk S, Eggersmann TK, Rohwedder I, Heinig K, Immler R, Moser M, Koedel U, Gran S, McEver RP, Vestweber D, Verschoor A, Leanderson T, Chavakis T, Roth J, Vogl T, Sperandio M. Extracellular MRP8/14 is a regulator of beta 2 integrin-dependent neutrophil slow rolling and adhesion.
Nat Commun 6.2015.
14. Schelbergen RF, Geven EJ, van den Bosch MHJ, Eriksson H, Leanderson T, Vogl T, Roth J, van de Loo FAJ, Koenders MI, van der Kraan PM, van den Berg WB, Blom AB, van Lent PLEM. Prophylactic treatment with S100A9 inhibitor paquinimod reduces pathology in experimental collagenase-induced osteoarthritis.
Annals of the Rheumatic Diseases 74:2254-2258.2015.
15. Schelbergen RFP, de Munter W, van den Bosch MHJ, Lafeber FPJG, Sloetjes A, Vogl T, Roth J, van den Berg WB, van der Kraan PM, Blom AB, van Lent PLEM. Alarmins S100A8/S100A9 aggravate osteophyte formation in experimental osteoarthritis and predict osteophyte progression in early human symptomatic osteoarthritis.
Annals of the Rheumatic Diseases 75:218-225.2016.
16. Van Crombruggen K, Vogl T, Perez-Novo C, Holtappels G, Bachert C. Differential release and deposition of S100A8/A9 proteins in inflamed upper airway tissue.
European Respiratory Journal 47:264-274.2016.
17. Verjans E, Ohl K, Reiss LK, van Wijk F, Toncheva AA, Wiener A, Yu Y, Rieg AD, Gaertner VD, Roth J, Knol E, Kabesch M, Wagner N, Uhlig S, Martin C, Tenbrock K. The cAMP response element modulator (CREM) regulates T(H)2 mediated inflammation.
Oncotarget 6:38538-38551.2015.
18. Wache C, Klein M, Ostergaard C, Angele B, Haecker H, Pfister H-W, Pruenster M, Sperandio M, Leanderson T, Roth J, Vogl T, Koedel U. Myeloid-Related Protein 14 Promotes Inflammation and Injury in Meningitis.
Journal of Infectious Diseases 212:247-257.2015.