Translational research
Chalas N, Daube C, Kluger DS, Abbasi O, Nitsch R, Gross J (in press). Speech onsets and sustained speech contribute differentially to delta and theta speech tracking in auditory cortex. Cereb Cortex
Endle H, Horta G, Stutz B, Muthuraman M, Tegeder I, Schreiber Y, Snodgrass IF, Gurke R, Liu ZW, Sestan-Pesa M, Radyushkin K, Streu N, Fan W, Baumgart J, Li Y, Kloss F, Groppa S, Opel N, Dannlowski U, Grabe HJ, Zipp F, Rácz B, Horvath TL, Nitsch R, Vogt J (2022). AgRP neurons control feeding behavior at cortical synapses via peripherally-derived lysophospholipids. Nature Metabolism 4(6):683-692. (full article)
Chalas, N., Daube, C., Kluger, D. S., Abbasi, O., Nitsch, R., & Gross, J. (2022) Multivariate analysis of speech envelope tracking reveals coupling beyond auditory cortex. NeuroImage, 119395. (full article)
Bitar L., Uphaus, T., Thalman C., Muthuraman M., Gyr L., Ji H., Domingues M., Endle H., Groppa S., Steffen F., Koirala N., Fan W., lbanez L., Heitsch L., Cruchaga C., Lee J.-M., Kloss F., Bittner S., Nitsch R.*, Zipp F.*, Vogt, J.* (2022) Inhibition of the enzyme autotaxin reduces cortical excitability and ameliorates the outcome in stroke. Science Translational Medicine 14,eabk0135. * equal contribution. (full article)
Thalman C*, Horta G*, Qiao L, Endle H, Tegeder I, Cheng H, Laube G, Sigurdsson T, Hauser MJ, Tenzer S, Distler U, Aoki J, Morris AJ, Geisslinger G, Röper J, Kirischuk S, Luhmann HJ, Radyushkin K, Nitsch R*, Vogt J* (2018) Synaptic phospholipids as a new target for cortical hyperexcitability and E/I balance in psychiatric disorders. Mol Psychiatry. 23(8):1699-1710. *equal contribution (full article)
Cheng J*, Sahani S*, Hausrat TJ*, Yang JW, Ji H, Schmarowski N, Endle H, Liu X, Li Y, Böttche R, Radyushkin K, Maric HM, Hoerder-Suabedissen A, Molnár Z, Prouvot PH, Trimbuch T, Ninnemann O, Huai J, Fan W, Visentin B, Sabbadini R, Strømgaard K, Stroh A, Luhmann HJ, Kneussel M, Nitsch R* Vogt J* (2016) Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling. Neuron. 5;92(1):126-142: *equal contribution (full article)
Vogt J*, Yang J*, Mobascher A*, Cheng J, Li J, Liu X, Baumgart J, Thalman C, Kirischuk S, Unichenko P, Horta G, Radyushkin K, Stroh A, Richers S, Sahragard N, Distler U, Tenzer S, Qiao L, Lieb K, Tüscher O, Binder H, Ferreiros N, Tegeder I, Morris A, Groppa S, Winterer G*, Luhmann H*, Huai J*, Nitsch R* (2016) Molecular cause and functional impact of altered synaptic lipid signaling due to a prg-1 gene SNP. EMBO Mol Med. 8: 25–38. *equal contribution; see also News & Views: Stutz B and Horvath TL (2016) Synaptic lipids in cortical function and psychiatric disorders EMBO Mol Med. 8: 3-5. (full article)
Trimbuch T*, Beed P*, Vogt J*, Schuchmann S, Maier N, Kintscher M, Breustedt J, Schuelke M, Streu N, Kieselmann O, Brunk I, Laube G, Strauss U, Battefeld A, Wende H, Birchmeier C, Wiese S, Sendtner M, Kawabe H, Kishimoto-Suga M, Brose N, Baumgart J, Geist B, Aoki J, Savaskan NE, Bräuer AU, Chun J, Ninnemann O, Schmitz D*, Nitsch R* (2009) Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling. Cell 138:1222-35. *equal contribution (full article)
Eljaschewitsch E, Witting A, Mawrin C, Lee T, Schmidt PM, Wolf S, Hörtnagl H, Raine CS, Schneider-Stock R, Nitsch R*, Ullrich O* (2006) The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in Microglial Cells. Neuron 49: 67-79. *equal contribution (full article)
Aktas O, Smorodchenko A, Brocke S, Infante-Duarte C, Topphoff US, Vogt J, Prozorovski T, Meier S, Osmanova V, Pohl E, Bechmann I, Nitsch R*, Zipp F* (2005) Neuronal damage in autoimmune neuroinflammation mediated by the death ligand TRAIL. Neuron 46:421-432. *equal contribution (full article)
Bräuer AU, Savaskan NE, Kühn H, Prehn S, Ninnemann O, Nitsch R (2003) A new phospholipid phosphatase, PRG-1, is involved in axon growth and regenerative sprouting. Nat Neurosci 6:572-78. (full article)
Ullrich O, Diestel A, Eyüpoglu I, Nitsch R (2001) Regulation of microglial expression of integrins by poly(ADP-ribose) polymerase-1. Nat Cell Biol 3:1035-42. (full article)
Nitsch R, Bechmann I, Deisz RA, Haas D, Lehmann TN, Wendling U, Zipp F (2000) Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL). Lancet 356:827-828. (full article)
Nitsch R and Frotscher M (1992) Reduction of posttraumatic transneuronal "early gene" activation and dendritic atrophy by the NMDA-receptor antagonist MK-801. Proc Natl Acad Sci USA 89: 5197-5200. (full article)