Scientific Mission

The Institute of Translational Neuroscience is an independent research institution at the Medical Faculty of the University Münster. It is dedicated to provide new options for diagnostic and/or therapeutic strategies for human diseases of the nervous system. This “bench to bedside” approach builds on molecular research pursued during the last 30 years which paved the avenue for novel therapeutic strategies to be assessed in man. It follows the idea that neuroscience is a discipline providing understanding of human disease and eventually its cure, rather than to explain man itself. Translation defines the goal of basic research, the patient. While experimental studies are pursued in close collaboration with the Institute of Anatomy, University of Cologne (Director: Prof. Dr. med. Johannes Vogt), clinical studies are performed in close collaboration with the Institute of Translational Psychiatry, University Münster (Director: Prof. Dr. med. Dr. phil. Udo Dannlowski).

In addition to translational research, philosophical aspects of the mind-body debate are addressed and a focus of the Institute’s teaching activities. The ever-recurring attempts of the neurosciences to explain all mental phenomena in physical terms alone are revised by critical reappraisal of classical concepts, e.g. Wilder Penfield’s “storehouse of memories”. Our analyzes question the idea of a realization of memory in solely naturalistic terms. These studies are performed in part at the Montreal Neurological Institute (Prof. Dr. Richard Leblanc, Prof. Dr. Jack Antel), Quebec, Canada, and in close collaboration with Prof. Dr. med. Frank Stahnisch at the Hotchkiss Brain Institute, University of Calgary, Alberta, Canada.

Latest publications

Fraiha-Pegado J, McWhinney SR, Alda M, Alexander N, Anmella G, Abé C, Altegoer L, Benedetti FH, Berk M, Bøen E, Bond DJ, Boye B, Bravi B, Cannon DM, Corkum ELV, Corley E, Dietze LMF, Dannlowski U, Elvsåshagen T, Fuentes-Claramonte P, Fullerton JM, Goldstein BI, Goltermann J, Grotegerd D, Hahn T, Hidalgo-Mazzei D, Im Y, Kang M, Karuk A, Kennedy KG, Kircher T, Klahn AL, Kraus A, Landén M, Leehr EJ, Machado-Vieira R, MacIntosh BJ, Malt UF, Mazza E, McDonald C, Meinert S, Melloni E, Mitchell PB, Nabulsi L, Nitsch R, O'Connor J, Opel N, Otaduy MCG, Overs BJ, Parker N, Poletti S, Pomarol-Clotet E, Radua J, Roberts G, Salvador R, Suo C, Schofield PR, Selitser M, Sim K, Straube B, Teutenberg L, Thomopoulos SI, Usemann P, Vieta E, Westlye LT, Wu L, Yatham LN, Thompson PM, Andreassen OA, Ching CRK, Hajek T; ENIGMA Bipolar Disorder and BMIx Working Groups (in press). The Link Between Weight Gain and Hippocampal Atrophy in Bipolar Disorder: A Longitudinal Investigation in 934 Participants. Biological Psychiatry. (full article)

Edwin Thanarajah S, Ribeiro AH, Lee J, Winter NR, Stein F, Lippert RN, Hanssen R, Schiweck C, Fehse L, Bloemendaal M, Aichholzer M, Bouzouina A, Uckermark C, Welzel M, Repple J, Matura S, Meinert S, Bang C, Franke A, Leenings R, Konowski M, Ernsting J, Fisch L, Barkhau C, Thomas-Odenthal F, Usemann P, Teutenberg L, Straube B, Alexander N, Jamalabadi H, Nenadic I, Lügering A, Nitsch R, Kittel-Schneider S, Cryan JF, Reif A, Kircher T, Heider D, Dannlowski U, Hahn T (in press). Soft Drink Consumption and Depression Mediated by Gut Microbiome Alterations. JAMA Psychiatry (full article)