C02: Publications

Reviews

  1. Ziegler C, Domschke K (2018)
    Epigenetic signature of MAOA and MAOB genes in mental disorders, J Neural Transm. 125:1581-1588.
  2. Ziegler C, Schiele MA, Domschke K (2018)
    Patho- und Therapieepigenetik psychischer Erkrankungen, Nervenarzt 89:1303-1314.
  3. Matthies S, Schiele MA, Koentges C, Pini S, Schmahl C, Domschke K (2018)
    Please don't leave me – separation anxiety in borderline personality disorder, Curr Psychiatry Rep, 20(10):83.
  4. Ströhle A, Gensichen J, Domschke K (2018)
    Angsterkrankungen, Dtsch Ärztebl Int, 155:611-620.
  5. Schiele MA, Domschke K (2018)
    Epigenetics at the crossroads between genes, environment and resilience in anxiety disorders, Genes Brain Behav, 17:e12423.
  6. Gottschalk MG, Domschke K (2016)
    Novel developments in genetic and epigenetic mechanisms of anxiety. Curr Opin Psychiatry, 29:32-8. 
  7. Schuebel K, Gitik M, Domschke K, Goldman D (2016)
    Making sense of epigenetics, Int J Neuropsychopharmacol, 19:1-10.

2018

  1. Neufang S, Geiger MJ, Homola GA, Mahr M, Schiele MA, Gehrmann A, Schmidt B, Gajewska A, Nowak J, Meisenzahl-Lechner E, Pham M, Romanos M, Deckert J, Akhrif A, Domschke K (2018)
    Cognitive-behavioral therapy effects on alerting network activity and effective connectivity in panic disorder, Eur Arch Psychiatry Clin Neurosci, in press 
  2. Schiele MA, Ziegler C, Kollert L, Katzorke A, Schwartner C, Busch Y, Gromer D, Pauli P, Deckert J, Herrmann MJ, Domschke K (2018)
    Plasticity of MAOA gene methylation: epigenetic correlate of treatment response in acrophobia, Int J Neuropsychopharmacology, 21:822-827.
  3. Schiele MA, Costa B, Abelli M, Martini C, Baldwin, Domschke K, Pini S (2018) Oxytocin receptor gene variation, behavioral inhibition, and adult separation anxiety – role in complicated grief, World J Biol Psychiatry, 19:471-479.
  4. Morimoto Y, Shimada-Sugimoto M, Otowa T, Yoshida S, Kinoshita A, Mishima H, Yamaguchi N, Mori T, Imamura A, Ozawa H, Kurotaki N, Ziegler C, Domschke K, Deckert J, Umekage T, Tochigi M, Kaiya H, Okazaki Y, Tokunaga K, Sasaki T, Yoshiura KI, Ono S (2018)
    Whole exome sequencing and gene-based rare variant association tests suggest that PLA2G4E might be a risk gene for panic disorder, Transl Psychiatry, 8:41.

2017

  1. Domschke K, Decker J (2017) 
    Prävention von Angststörungen. In: Joachim Klosterkötter, Wolfgang Maier (Hrsg.):  Handbuch Präventive Psychiatrie, Forschung - Lehre - Versorgung,  Schattauer,  1. Auflage  2017, S153-176.
  2. Schartner C, Ziegler C, Schiele M, Kollert L, Weber H, Zwanzger P, Arolt V, Pauli P, Reif A, Deckert J, Domschke K (2017)
    CRHR1 promoter hypomethylation: An epigenetic readout of panic disorder? Eur Neuropsychopharmacol, 27:360-371.

2015

  1. Domschke K, Akhrif A, Bajer C, Mainusch M, Romanos M, Winkelmann J, Zimmer C, Neufang S (2015)
    Neuropeptide S receptor gene modulates the development of fronto-limbic effective connectivity. Cereb Cortex, in press, doi: 10.1093/cercor/bhv259.
  2. Domschke K, Tidow N, Schwarte K, Ziegler C, Lesch KP, Deckert J, Arolt V, Zwanzger P, Baune BT (2015)
    Pharmacoepigenetics of depression – No major influence of MAO-A DNA methylation on treatment response. J Neural Transm 122:99-108.
  3. Domschke K*, Winter B*, Gajewska A, Unterecker S, Warrings B, Dlugos A, Notzon S, Nienhaus K, Gieselmann A, Herrmann MJ, Jacob C, Arolt V, Mühlberger A, Reif A, Pauli P, Deckert J, Zwanzger P (2015)
    Multilevel impact of the dopamine system on the emotion-potentiated startle reflex. Psychopharmacology 232:1983-1993.
  4. Neufang S, Geiger M, Homola G, Mahr M, Nowak J, Reif A, Pauli P, Romanos M, Solymosi L, Deckert J, Domschke K (2015)
    Modulation of prefrontal functioning in attentional neural networks by NPSR1 gene variation. NeuroImage 14:199-206.
  5. Ruland T*, Domschke K*, Schütte V, Zavorotnyy M, Kugel H, Notzon S, Vennewald N, Ohrmann P, Arolt V, Pfleiderer B, Zwanzger P (2015)
    Neuropeptide S receptor gene variation modulates glutamatergic anterior cingulate cortex activity during CCK-4 induced panic. Eur Neuropsychopharmacol, in press, doi: 10.1016/j.euroneuro.2015.07.011. 
  6. Ziegler C*, Dannlowski U*, Braeuer D*, Stevens S, Laeger I, Wittmann H, Tidow N, Mahr M, Kugel H, Heindel W, Dobel C, Hurlemann R, Reif A, Lesch KP, Arolt V, Gerlach A, Hoyer J, Deckert J, Zwanzger P, Domschke K (2015)
    Oxytocin receptor (OXTR) gene methylation – converging evidence for a role in social anxiety. Neuropsychopharmacology 40:1528-1538.

2014

  1. Domschke K, Tidow N, Schwarte K, Deckert J, Lesch KP, Arolt V, Zwanzger P, Baune BT (2014)
    Serotonin transporter gene hypomethylation predicts impaired antidepressant treatment response. Int J Neuropsychopharmacol 17:1167-1176.
  2. Schraut KG, Jakob SB, Weidner MT, Schmitt AG, Scholz CJ, El Hajj N, Eijssen L, Domschke K, Reif A, Haaf T, Ortega G, Steinbusch HWM, Van den Hove DL, Lesch KP (2014) Prenatal stress-induced programming of genome-wide promoter DNA methylation in 5‑HTT deficient mice. Transl Psychiatry 24:e473.

2013

  1. Beste C, Konrad C, Uhlmann C, Arolt V, Zwanzger P, Domschke K (in press) Neuropeptide S receptor (NPSR1) gene variation modulates response inhibition and error monitoring, NeuroImage.  
  2. Diemer J, Domschke K, Mühlberger A, Winter B, Zavorotnyy M, Naunin S, Silling K, Arolt V, Zwanzger P (in press) Acute anxiolytic effects of quetiapine during virtual reality exposure – a double-blind placebo-controlled trial in patients with specific phobia, Eur Neuropsychopharm
  3. Dresler T, Guhn A, Tupak SV, Ehlis AC, Herrmann MJ, Fallgatter AJ, Deckert J, Domschke K (2013) Revise the revised? New dimensions of the neuroanatomical hypothesis of panic disorder. J Neural Transm 120: 3-29.
  4. Erhardt A, Akula N, Schumacher J, Czamara D, Karbalai N, Müller-Myhsok B, Mors O, Borglum A, Kristensen AS, Woldbye DPD, Koefoed P, Eriksson E, Maron E, Metspalu A, Nurnberger J, Philibert RA, Kennedy J, Domschke K, Reif A, Deckert J, Otowa T, Kawamura Y, Kaiya H, Okazaki Y, Tanii H, Tokunaga K, Sasaki T, Ioannidis JPA, McMahon FJ, Binder EB (in press) Replication and meta-analysis of TMEM132D gene variants in panic disorder, Transl Psychiatry.
  5. Gajewska A, Blumenthal TD, Winter B, Herrmann MJ, Warrings B, Mühlberger A, Jacob C, Arolt V, Reif A, Zwanzger P, Pauli P, Deckert J, Domschke K (2013) Effects of ADORA2A gene variation and caffeine on prepulse inhibition – a multi-level risk model of anxiety, Prog Neuropsychopharmacol Biol Psychiatry 40:115-121.
  6. Klauke B, Deckert J, Zwanzger P, Baumann C, Arolt V, Pauli P, Reif A, Domschke K (in press) Neuropeptide S receptor gene (NPSR) and life events: GxE effects on anxiety sensitivity and its subdimensions. World J Biol Psychiatry, DOI 10.3109/15622975.2011.646302.
  7. Reif A, Richter J, Straube B, Höfler M Lüken U, Gloster AT, Weber H, Domschke K, Fehm L, Ströhle A, Jansen A, Gerlach A, Pyka M, Reinhardt I, Konrad C, Wittmann G, Pfleiderer B, Alpers GW, Pauli P, Arolt V, Wittchen HU, Hamm A, Kircher T, Deckert J (in press) MAOA and mechanisms of panic disorder revisited: from bench to molecular psychotherapy, Mol Psychiatry
  8. Domschke K*, Tidow N*, Schrempf M, Schwarte K, Klauke B, Reif A, Kersting A, Arolt V, Zwanzger P, Deckert J (2013)
    Epigenetic signature of panic disorder: a role of glutamate decarboxylase 1 (GAD1) DNA hypomethylation? Prog Neuropsychopharmacol Biol Psychiatry 46C:189-196.

2012

  1. Domschke K (2012) Patho-genetics of posttraumatic stress disorder. Psychiatr Danub 24: 267-273.
  2. Domschke K, Baune BT, Havlik L, Stuhrmann A, Suslow T, Kugel H, Zwanzger P, Grotegerd D, Sehlmeyer C, Arolt V, Dannlowski U (2012 a) Catechol-O-methyltransferase gene variation: Impact on amygdala response to aversive stimuli. NeuroImage 60: 2222-2229.
  3. Domschke K, Deckert J (2012) Genetics of anxiety disorders – Status quo and quo vadis, Curr Pharm Des 18: 5691-5698.
  4. Domschke K, Gajewska A, Winter B, Herrmann MJ, Warrings B, Mühlberger A, Wosnitza K, Glotzbach E, Conzelmann A, Dlugos A, Fobker M, Jacob C, Arolt V, Reif A, Pauli P, Zwanzger P, Deckert J (2012) ADORA2A gene variation, caffeine and emotional processing – a multi-level interaction on startle reflex. Neuropsychopharmacology 37: 759-769.
  5. Domschke K, Klauke B, Winter B, Gajewska A, Herrmann MJ, Warrings B, Mühlberger A, Wosnitza K, Dlugos A, Fobker M, Jacob C, Arolt V, Reif A, Pauli P, Zwanzger P, Deckert J (2012) Modulation of caffeine effects on the emotion-potentiated startle by neuropeptide S receptor (NPSR) gene variation. Psychopharmacology 222: 533-541.
  6. Domschke K, Tidow N, Kuithan H, Schwarte K, Klauke B, Ambrée O, Reif A, Schmidt H, Arolt V, Kersting A, Zwanzger P, Deckert J (2012) Monoamine oxidase A gene DNA hypomethylation - a risk factor for panic disorder? Int J Neuropsychopharmacol 15: 1217-1228.
  7. Klauke B, Winter B, Gajewska A, Zwanzger P, Reif A, Herrmann MJ, Dlugos A, Warrings B, Jacob C, Mühlberger A, Arolt V, Pauli P, Deckert J, Domschke K (2012) Affect-modulated startle: Interactive influence of Catechol-O-methyltransferase Val158Met genotype and childhood trauma. PloSONE 7(6): e39709.
  8. Reif A, Weber H, Domschke K, Klauke B, Baumann C, Jacob CP, Ströhle A, Gerlach A, Alpers GW, Pauli P, Hamm A, Kircher T, Arolt V, Wittchen HU, Binder EB, Erhardt A, Deckert J (2012) Meta-analysis argues for a female-specific role of MAOA-uVNTR in panic disorder in four European populations. Am J Med Genet B (Neuropsychiatr Genet) 159B: 786-793.  
  9. Tupak SV, Reif A, Pauli P, Dresler T, Herrmann MJ, Domschke K, Jochum C, Haas C, Baumann C, Weber H, Fallgatter AJ, Deckert J, Ehlis AC (2012) Neuropeptide S receptor gene: Fear-specific modulations of prefrontal activation. NeuroImage 66: 353-360.  
  10. Weber H, Scholz CJ, Domschke K, Baumann C, Klauke B, Jacob CP, Maier W, Fritze J, Bandelow B, Zwanzger P, Lang T, Fehm L, Ströhle A, Hamm A, Gerlach AL, Alpers GW, Kircher T, Wittchen HU, Arolt V, Pauli P, Deckert J, Reif A (2012) Gender differences in associations of glutamate decarboxylase 1 gene (GAD1) variants with panic disorder. PloS ONE 7: e37651.  
  11. Zwanzger P, Domschke K, Bradwejn J (2012) The neuronal network of panic: the role of the neuropeptide cholecystokinin, Depress Anxiety 29: 762-774.

2011

  1. Dannlowski U, Kugel H, Franke F, Hohoff C, Zwanzger P, Lenzen T, Grotegerd D, Suslow T, Arolt V, Heindel W, Domschke K (2011) Neuropeptide S (NPS) receptor genotype modulates basolateral amygdala responsiveness to aversive stimuli. Neuropsychopharmacology 36: 1879-1885.
  2. Domschke K, Reif A, Weber H, Richter J, Hohoff C, Ohrmann P, Pedersen A, Bauer J, Suslow T, Kugel H, Heindel W, Baumann C, Klauke B, Jacob C, Maier W, Fritze J, Bandelow B, Krakowitzky P, Rothermundt M, Erhardt A, Binder E, Holsboer F, Gerlach A, Kircher T, Lang T, Alpers G, Ströhle A, Fehm L, Gloster A, Wittchen HU, Arolt V, Pauli P, Hamm A, Deckert J (2011) Neuropeptide S receptor (NPSR) gene – converging evidence for a role in panic disorder. Mol Psychiatry 16: 938-948.  
  3. Erhardt A, Czibere L, Roeske D, Lucae S, Unschuld PG, Ripke S, Specht M, Kohli MA, Kloiber S, Ising M, Heck A, Pfister H, Zimmermann P, Lieb R, Puetz B, Uhr M, Weber P, Deussing JM, Gonic M, Bunck M, Keßler MS, Frank E, Hohoff C, Domschke K, Krakowitzky P, Maier W, Bandelow B, Jacob C, Deckert J, Schreiber S, Strohmaier J, Noethen M, Cichon S, Rietschel M, Bettecken T, Keck ME, Landgraf R, Müller-Myhsok B, Holsboer F, Binder EB (2011) TMEM132D a new candidate for anxiety phenotypes: evidence from human and mouse studies. Mol Psychiatry 16: 647-663.
  4. Klauke B, Deckert J, Reif A, Pauli P, Zwanzger P, Baumann C, Glöckner-Rist A, Domschke K (2011) Serotonin transporter gene and childhood trauma – a GxE effect on anxiety sensitivity. Depress Anxiety 28: 1048-1057.

2010

  1. Diemer J, Vennewald N, Domschke K, Zwanzger P (2010) Therapy-refractory panic – current research areas as possible perspectives in the treatment of anxiety. Eur Arch Psychiatry Clin Neurosci 260: 127-131.
  2. Domschke K, Dannlowski U (2010) Imaging genetics of anxiety disorders. NeuroImage 53: 822-831.
  3. Domschke K, Deckert J (2010) Genetics. Curr Top Behav Neurosci 2: 63-75.
  4. Domschke K, Stevens S, Pfleiderer B, Gerlach A (2010) Interoceptive sensitivity in anxiety and anxiety disorders: an overview and integration of neurobiological findings, Clin Psychol Rev 30: 1-11.
  5. Hohoff C, Mullings EL, Heatherley SV, Freitag C, Neumann L, Domschke K, Krakowitzky P, Rothermundt M, Keck ME, Erhardt A, Binder EB, Jacob C, Fritze J, Bandelow B, Maier W, Holsboer F, Rogers PJ, Deckert J (2010) Adenosine A2A receptor gene: Evidence for association of risk variants with panic disorder and anxious personality. J Psychiatr Res 44: 930-937.
  6. Jacob C, Domschke K, Gajewska A, Warrings B, Deckert J (2010) Neurogenetics of panic disorder - focus on association studies and therapeutic perspectives. Expert Rev Neurother 10: 1273-1284.  
  7. Klauke B, Deckert J, Reif A, Pauli P, Domschke K (2010) Life events in panic disorder - An update on “candidate stressors”, Depress Anxiety 27: 716-730.

2008

  1. Domschke K, Zwanzger P (2008) GABAergic and endocannabinoid dysfunction in anxiety - future therapeutic targets? Curr Pharm Des 14: 3508-3517.