Institute for Cardiovascular Organogenesis and Regeneration

Tracking the vascular und nervous system

The cells of the vascular and nervous system make their own higly branched network in the body. Yet, both systems are in close contact with each other. There are still many open questions as to how exactly they are connected to each other. Scientists from Münster, Frankfurt (Main), Heidelberg, Karlsruhe and Berlin now aim to find answers to these questions in a Research Unit, financed by the Deutsche Forschungsgemeinschaft (DFG). Read more ...

Photo gallery: "Lange Nacht der Universitätsmedizin" - Impressions from the Multiscale Imaging Centre

Dr. rer. nat. Andreas van Impel explains to visitors how studying blood and lymph vessel development in zebrafish can provide insights into cardiovascular diseases in humans.
©Uni Münster - Michael Kuhlmann

ICOR took part in the 100-year anniversary celebrations of the Faculty of Medicine and University Hospital of Münster. Our Institute showcased the group’s research on cardiovascular science and regeneration. Visitors had the chance to observe a beating heart of a zebrafish embryo under the microscope, learn about our research using zebrafish, and even try a hands-on activity by collecting zebrafish eggs with practice dummies. Read more…

Travel Grant Award for the Gordon Research Conference

William Repicci (President LE&RN), Sanjay Sunil Kumar, Prof. Stefan Schulte-Merker

The Gordon Research Conference (GRC) for Lymphatics is the premier research conference for scientists studying lymphatic development and disease. The GRC shuttles between California, USA and Lucca, Italy. In February 2024, Sanjay Sunil Kumar from the Institute for Cardiovascular Organogenesis and Regeneration (ICOR) attended the GRC lymphatics in Ventura, California, USA. Sanjay was supported by the Cells In Motion Interfaculty Centre Travel Award as well as the Lymphatic Education and Research Network GRC Travel Award. During the 6 day conference, Sanjay presented his unpublished work on lymphatic vessel development which received extremely positive feedback from the lymphatic community which consists of basic researchers, clinicians and policymakers. Furthermore, Sanjay was recognized for his work and was awarded the best Presentation and Poster prize during the conference. 'I'm extremely grateful to Stefan Schulte-Merker, CiM Interfaculty Centre and LERN for giving me the support to attend and communicate my findings during this conference. The conference provided me the opportunity to interact and gain valuable feedback from key players in the field.'

"Paper of the Month 5/2023" for ICOR

Dr. Dörte Schulte (l.), Melina Hußmann und Prof. Schulte-Merker

Congratulations to our PhD student Melina Hußmann for "Paper of the Month 5/2023"!

Her paper Svep1 is a binding ligand of Tie1 and affects specific aspects of facial lymphatic development in a Vegfc-independent manner, showing the interaction of extra-cellular matrix protein SVEP1 with the TIE1 receptor in zebrafish lymphangiogenesis, was selected as "Paper of the Month" by the Faculty of Medicine. Read more...

Hußmann, M.; Schulte, D.; (...); Schulte-Merker, S. APR 2023 | eLife

Zebrafische liefern die Erklärung: Forscher finden "Hotspots" für die Entwicklung von Lymphgefäßen

Sich entwickelnde Lymphgefäße im Zebrafisch: Zellen des Bindegewebes (Fibroblasten, grün) exprimieren das Protein VEGF-C und beeinflussen die Migration von lymphatischen Endothelzellen (rot) (Abb.: A. van Impel)

Münster (upm/sr)- Entwickelt sich ein Embryo, setzen die verschiedenen Proteine und Enzyme eine Reihe von biochemischen Reaktionen in Gang. Eine Hauptrolle bei der Entwicklung von...

Genome Engineering Workshop

On June 27/28 a Workshop on Zebrafish Genome Engineering attracted the attention of 108 international participants. The workshop was organized by S.Schulte-Merker and W.Herzog (both WWU Münster), A.Acker-Palmer (Univ Frankfurt) and F. le Noble (Univ Karlsruhe), featuring 6 speakers from the US, Germany, the UK and France. Intense discussions focused on how to implement CRISPR/Cas and TALEN Technologies to enable knock in and homologous recombination events in zebrafish.