Selected publications since 2000

click here for complete publication list in pubmed.

2022
 
Hartmann C, Thüring EM, Greune L, Michels BE, Pajonczyk D, Leußink S, Brinkmann F, Glaesner-Ebnet M, Wardelmann E, Zobel T, Schmidt MA, Janssen KP, Gerke V, Ebnet K.
Intestinal brush border formation requires a TMIGD1-based intermicrovillar adhesion complex.
Sci Signal. 2022 Sep 13;15(751):eabm2449. doi: 10.1126/scisignal.abm2449. Epub 2022 Sep 13.
PMID:36099341
 
Wegner T, Elias R, Roling L, Raj N, Gerke V, Fridman M, Glorius F.
Cationic, Steroid-Based Imidazolium Amphiphiles Show Tunable Backbone-Dependent Membrane Selectivity in Fungi.
ACS Infect Dis. 2022 Sep 9;8(9):1815-1822. doi: 10.1021/acsinfecdis.2c00164. Epub 2022 Aug 29.
PMID:36036536
 
Ebnet K, Gerke V.
Rho and Rab Family Small GTPases in the Regulation of Membrane Polarity in Epithelial Cells.
Front Cell Dev Biol. 2022 Jul 4;10:948013. doi: 10.3389/fcell.2022.948013. eCollection 2022.
PMID:35859901
 
Terglane J, Menche D, Gerke V.
Acidification of endothelial Weibel-Palade bodies is mediated by the vacuolar-type H+-ATPase.
PLoS One. 2022 Jun 29;17(6):e0270299. doi: 10.1371/journal.pone.0270299. eCollection 2022.
PMID:35767558
 
Brandt M, Gerke V, Betz T.
Human endothelial cells display a rapid tensional stress increase in response to tumor necrosis factor-α.
PLoS One. 2022 Jun 24;17(6):e0270197. doi: 10.1371/journal.pone.0270197. eCollection 2022.
PMID:35749538
 
Naß J, Koerdt SN, Biesemann A, Chehab T, Yasuda T, Fukuda M, Martín-Belmonte F, Gerke V.
Tip-end fusion of a rod-shaped secretory organelle.
Cell Mol Life Sci. 2022 Jun 4;79(6):344. doi: 10.1007/s00018-022-04367-2.
PMID:35660980
 
Kummer D, Steinbacher T, Thölmann S, Schwietzer MF, Hartmann C, Horenkamp S, Demuth S, Peddibhotla SSD, Brinkmann F, Kemper B, Schnekenburger J, Brandt M, Betz T, Liashkovich I, Kouzel IU, Shahin V, Corvaia N, Rottner K, Tarbashevich K, Raz E, Greune L, Schmidt MA, Gerke V, Ebnet K.
A JAM-A-tetraspanin-αvβ5 integrin complex regulates contact inhibition of locomotion.
J Cell Biol. 2022 Apr 4;221(4):e202105147. doi: 10.1083/jcb.202105147. Epub 2022 Mar 16.
PMID: 35293964
 
Schloer S, Goretzko J, Rescher U.
Repurposing Antifungals for Host-Directed Antiviral Therapy?
Pharmaceuticals (Basel). 2022 Feb 10;15(2):212. doi: 10.3390/ph15020212.
PMID:35215323 Review.
 
Holthenrich A, Terglane J, Naß J, Mietkowska M, Kerkhoff E, Gerke V.
Spire1 and Myosin Vc promote Ca2+-evoked externalization of von Willebrand factor in endothelial cells.
Cell Mol Life Sci. 2022 Jan 27;79(2):96. doi: 10.1007/s00018-021-04108-x.
PMID: 35084586
 
Thölmann S, Seebach J, Otani T, Florin L, Schnittler H, Gerke V, Furuse M, Ebnet K.
JAM-A interacts with α3β1 integrin and tetraspanins CD151 and CD9 to regulate collective cell migration of polarized epithelial cells.
Cell Mol Life Sci. 2022 Jan 24;79(2):88. doi: 10.1007/s00018-022-04140-5.
PMID:35067832
 
2021

Naß J, Terglane J, Gerke V.
Weibel Palade Bodies: Unique Secretory Organelles of Endothelial Cells that Control Blood Vessel Homeostasis.
Front Cell Dev Biol. 2021 Dec 16;9:813995. doi: 10.3389/fcell.2021.813995. eCollection 2021.
PMID:34977047 Review.
 
Kudruk S, Pottanam Chali S, Linard Matos AL, Bourque C, Dunker C, Gatsogiannis C, Ravoo BJ, Gerke V.
Biodegradable and Dual-Responsive Polypeptide-Shelled Cyclodextrin-Containers for Intracellular Delivery of Membrane-Impermeable Cargo.
Adv Sci (Weinh). 2021 Sep;8(18):e2100694. doi: 10.1002/advs.202100694. Epub 2021 Jul 18.
PMID:34278745
 
Brunotte L, Zheng S, Mecate-Zambrano A, Tang J, Ludwig S, Rescher U, Schloer S.
Combination Therapy with Fluoxetine and the Nucleoside Analog GS-441524 Exerts Synergistic Antiviral Effects against Different SARS-CoV-2 Variants In Vitro.
Pharmaceutics. 2021 Sep 3;13(9):1400. doi: 10.3390/pharmaceutics13091400.
PMID:34575474
 
Matos ALL, Keller F, Wegner T, Del Castillo CEC, Grill D, Kudruk S, Spang A, Glorius F, Heuer A, Gerke V.
Author Correction: CHIMs are versatile cholesterol analogs mimicking and visualizing cholesterol behavior in lipid bilayers and cells.
Commun Biol. 2021 Aug 26;4(1):1023. doi: 10.1038/s42003-021-02570-8.
PMID:34446832
 
Raabe CA, Rescher U.
Can you teach an old receptor new tricks?
J Leukoc Biol. 2021 Aug;110(2):217-218. doi: 10.1002/JLB.2CE0920-568R. Epub 2020 Nov 6.
PMID:33155721

Brabenec L, Müller M, Hellenthal KEM, Karsten OS, Pryvalov H, Otto M, Holthenrich A, Matos ALL, Weiss R, Kintrup S, Hessler M, Dell'Aquila A, Thomas K, Naß J, Margraf A, Nottebaum AF, Rossaint J, Zarbock A, Vestweber D, Gerke V, Wagner NM.
Targeting Procalcitonin Protects Vascular Barrier Integrity.
Am J Respir Crit Care Med. 2022 Aug 15;206(4):488-500. doi: 10.1164/rccm.202201-0054OC.
PMID:35699655
 
Fitzian K, Brückner A, Brohée L, Zech R, Antoni C, Kiontke S, Gasper R, Linard Matos AL, Beel S, Wilhelm S, Gerke V, Ungermann C, Nellist M, Raunser S, Demetriades C, Oeckinghaus A, Kümmel D.
TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation.
Mol Cell. 2021 Jul 1;81(13):2705-2721.e8. doi: 10.1016/j.molcel.2021.04.019. Epub 2021 May 10.
PMID:33974911
 
Ashraf APK, Gerke V.
Plasma membrane wound repair is characterized by extensive membrane lipid and protein rearrangements in vascular endothelial cells.
Biochim Biophys Acta Mol Cell Res. 2021 Jun;1868(7):118991. doi: 10.1016/j.bbamcr.2021.118991. Epub 2021 Mar 2.
PMID:33667528
 
Schloer S, Brunotte L, Mecate-Zambrano A, Zheng S, Tang J, Ludwig S, Rescher U.
Drug synergy of combinatory treatment with remdesivir and the repurposed drugs fluoxetine and itraconazole effectively impairs SARS-CoV-2 infection in vitro.
Br J Pharmacol. 2021 Jun;178(11):2339-2350. doi: 10.1111/bph.15418. Epub 2021 Apr 6.
PMID:33825201
 
Matos ALL, Keller F, Wegner T, Del Castillo CEC, Grill D, Kudruk S, Spang A, Glorius F, Heuer A, Gerke V.
CHIMs are versatile cholesterol analogs mimicking and visualizing cholesterol behavior in lipid bilayers and cells.
Commun Biol. 2021 Jun 11;4(1):720. doi: 10.1038/s42003-021-02252-5.
PMID:34117357
 
Kurka DW, Niehues M, Kudruk S, Gerke V, Ravoo BJ.
Polythiolactone-Decorated Silica Particles: A Versatile Approach for Surface Functionalization, Catalysis and Encapsulation.
Chemistry. 2021 May 17;27(28):7667-7676. doi: 10.1002/chem.202100547. Epub 2021 May 2.
PMID:33788322
 
Gerke V, Rescher U.
ANO5 in membrane repair - Status: "It's complicated".
Cell Calcium. 2021 Apr 27;97:102415. doi: 10.1016/j.ceca.2021.102415. Online ahead of print.
PMID:33934044
 
Grewal T, Rentero C, Enrich C, Wahba M, Raabe CA, Rescher U.
Annexin Animal Models-From Fundamental Principles to Translational Research.
Int J Mol Sci. 2021 Mar 26;22(7):3439. doi: 10.3390/ijms22073439.
PMID:33810523Review.

Ashraf APK, Koerdt SN, Raj N, Gerke V.
Induction of Ca2+-Dependent Exocytotic Processes by Laser Ablation of Endothelial Cells.
Methods Mol Biol. 2021;2233:287-300. doi: 10.1007/978-1-0716-1044-2_19.
PMID: 33222142

2020

Merlen G, Kahale N, Ursic-Bedoya J, Bidault-Jourdainne V, Simerabet H, Doignon I, Tanfin Z. Garcin I, Pean N, Gautherot J, Davit-Spraul A, Guettier C, Humbert L, Rainteau D, Ebnet K, Ullmer C, Cassio D, Tordjmann T
TGR5-dependent hepatoprotection through the regulation of biliary epithelium barrier function.
Gut. 2020 Jan;69(1):146-157. doi: 10.1136/gutjnl-2018-316975. Epub 2019 Feb 5.
PMID: 30723104

Kummer D, Steinbacher T, Schwietzer MF, Thölmann S, Ebnet K.
Tetraspanins: integrating cell surface receptors to functional microdomains in homeostasis and disease.
Med Microbiol Immunol. 2020 Aug;209(4):397-405. doi: 10.1007/s00430-020-00673-3. Epub 2020 Apr 9.
PMID: 32274581

Hartmann C, Schwietzer YA, Kummer D, Kirschnick N, Hoppe E, Thüring EM, Glaesner-Ebnet M, Brinkmann F, Gerke V, Reuter S, Nakayama M, Ebnet K.
The mitochondrial outer membrane protein SYNJ2BP interacts with the cell adhesion molecule TMIGD1 and can recruit it to mitochondria.
BMC Mol Cell Biol. 2020 Apr 17;21(1):30. doi: 10.1186/s12860-020-00274-1.
PMID: 32303178

Gröper J, König GM, Kostenis E, Gerke V, Raabe CA, Rescher U.
Exploring Biased Agonism at FPR1 as a Means to Encode Danger Sensing.
Cells. 2020 Apr 23;9(4):1054. doi: 10.3390/cells9041054.
PMID: 32340221

Matos ALL, Kudruk S, Moratz J, Heflik M, Grill D, Ravoo BJ, Gerke V.
Membrane Binding Promotes Annexin A2 Oligomerization.
Cells. 2020 May 8;9(5):1169. doi: 10.3390/cells9051169.
PMID: 32397265

Boltersdorf T, Ansari J, Senchenkova EY, Groeper J, Pajonczyk D, Vital SA, Kaur G, Alexander JS, Vogl T, Rescher U, Long NJ, Gavins FNE.
Targeting of Formyl Peptide Receptor 2 for in vivo imaging of acute vascular inflammation.
Theranostics. 2020 May 17;10(15):6599-6614. doi: 10.7150/thno.44226. eCollection 2020.
PMID: 32550892

Schloer S, Goretzko J, Pleschka S, Ludwig S, Rescher U.
Combinatory Treatment with Oseltamivir and Itraconazole Targeting Both Virus and Host Factors in Influenza A Virus Infection.
Viruses. 2020 Jun 29;12(7):703. doi: 10.3390/v12070703.
PMID: 32610711

Haas AJ, Zihni C, Ruppel A, Hartmann C, Ebnet K, Tada M, Balda MS, Matter K.
Interplay between Extracellular Matrix Stiffness and JAM-A Regulates Mechanical Load on ZO-1 and Tight Junction Assembly.
Cell Rep. 2020 Jul 21;32(3):107924. doi: 10.1016/j.celrep.2020.107924.
PMID: 32697990

Nguyen TTN, Koerdt SN, Gerke V.
Plasma membrane phosphatidylinositol (4,5)-bisphosphate promotes Weibel-Palade body exocytosis.
Life Sci Alliance. 2020 Aug 21;3(11):e202000788. doi: 10.26508/lsa.202000788. Print 2020 Nov.
PMID: 32826291

Heinick A, Pluteanu F, Hermes C, Klemme A, Domnik M, Husser X, Gerke V, Schmitz W, Müller FU.
Annexin A4 N-terminal peptide inhibits adenylyl cyclase 5 and limits β-adrenoceptor-mediated prolongation of cardiac action potential.
FASEB J. 2020 Aug;34(8):10489-10504. doi: 10.1096/fj.201902094RR. Epub 2020 Jun 24.
PMID: 32579290

Raabe CA, Rescher U.
Can you teach an old receptor new tricks?
J Leukoc Biol. 2020 Nov 6. doi: 10.1002/JLB.2CE0920-568R. Online ahead of print.
PMID: 33155721

Rescher U, Gerke V, Lim LHK, Jaiswal JK.
Special Issue "Recent Developments in Annexin Biology".
Cells. 2020 Nov 14;9(11):2477. doi: 10.3390/cells9112477.
PMID: 33202541

Schlesier T, Siegmund A, Rescher U, Heilmann C.
Characterization of the Atl-mediated staphylococcal internalization mechanism.
Int J Med Microbiol. 2020 Dec;310(8):151463. doi: 10.1016/j.ijmm.2020.151463. Epub 2020 Oct 28.
PMID: 33197865

Schloer S, Brunotte L, Goretzko J, Mecate-Zambrano A, Korthals N, Gerke V, Ludwig S, Rescher U.
Targeting the endolysosomal host-SARS-CoV-2 interface by clinically licensed functional inhibitors of acid sphingomyelinase (FIASMA) including the antidepressant fluoxetine.
Emerg Microbes Infect. 2020 Dec;9(1):2245-2255. doi: 10.1080/22221751.2020.1829082.
PMID: 32975484

Paulisch TO, Bornemann S, Herzog M, Kudruk S, Roling L, Linard Matos AL, Galla HJ, Gerke V, Winter R, Glorius F.
An Imidazolium-Based Lipid Analogue as a Gene Transfer Agent.
Chemistry. 2020 Dec 18;26(71):17176-17182. doi: 10.1002/chem.202003466. Epub 2020 Nov 9.
PMID: 32720444

Gerke, V
Von Willebrand factor folds into a bouquet.
EMBO J. 2011 Oct 5;30(19):3880-1. doi: 10.1038/emboj.2011.321. 

Rojo Pulido I, Nightingale TD, Darchen F, Seabra MC, Cutler DF, Gerke V.
Myosin Va Acts in Concert with Rab27a and MyRIP to Regulate Acute Von-Willebrand Factor Release from Endothelial Cells.
Traffic. 2011 Oct;12(10):1371-1382. doi: 10.1111/j.1600-0854.2011.01248.x. Epub 2011 Aug 5.

Pulido IR, Jahn R, Gerke V
VAMP3 is associated with endothelial weibel-palade bodies and participates in their Ca(2+)-dependent exocytosis.
Biochim Biophys Acta. 2011;1813(5): 1038-44

Bosk S, Braunger JA, Gerke V, Steinem C
Activation of F-actin binding capacity of ezrin: synergism of PIP2 interaction and phosphorylation.
Biophys J. 2011;100(7): 1708-17

Heil A, Nazmi AR, Koltzscher M. Poeter M., Austermann J, Assard N, Baudier J, Kaubuchi K, Gerke V
S100P is a novel interaction partner and regulator of IQGAP1.
J Biol Chem. 2011;286(9): 7227-38 

Gauthier-Kemper A, Weissmann C, Golovyashkina N, Sebö-Lemke Z, Drewes G, Gerke V, Heinisch JJ, Brandt R.
The frontotemporal dementia mutation R406W blocks tau's interaction with the membrane in an annexin A2-dependent manner.
J Cell Biol. 2011 Feb 21;192(4):647-61. Pubmed

Pupjalis D, Goetsch J, Kottas DJ, Gerke V, Rescher U.
Annexin A1 released from apoptotic cells acts through formyl peptide receptors to dampen inflammatory monocyte activation via JAK/STAT/SOCS signalling.
EMBO Mol Med. 2011 Feb;3(2):102-14. Pubmed

Patel DM, Ahmad SF, Weiss DG, Gerke V, Kuznetsov SA.
Annexin A1 is a new functional linker between actin filaments and phagosomes during phagocytosis.
J Cell Sci. 2011 Feb 15;124(Pt 4):578-88. Pubmed

Heil A, Nazmi AR, Koltzscher M, Poeter M, Austermann J, Assard N, Baudier J, Kaibuchi K, Gerke V.
S100P is a novel interaction partner and regulator of IQGAP1.
J Biol Chem. 2010 Dec 22. Pubmed

Pulido IR, Jahn R, Gerke V.
VAMP3 is associated with endothelial Weibel-Palade bodies and participates in their Ca(2+)-dependent exocytosis.
Biochim Biophys Acta. 2010 Nov 20. Pubmed

Markoff A, Gerdes S, Feldner S, Bogdanova N, Gerke V, Grandone E.
Reduced allele specific annexin A5 mRNA levels in placentas carrying the M2/ANXA5 allele.
Placenta. 2010 Oct;31(10):937-40. Pubmed

Backes P, Quinkert D, Reiss S, Binder M, Zayas M, Rescher U, Gerke V, Bartenschlager R, Lohmann V.
Role of annexin A2 in the production of infectious hepatitis C virus particles.
J Virol. 2010 Jun;84(11):5775-89. Pubmed

Choudhary C, Olsen JV, Brandts C, Cox J, Reddy PN, Böhmer FD, Gerke V, Schmidt-Arras DE, Berdel WE, Müller-Tidow C, Mann M, Serve H.
Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes.
Mol Cell. 2009 Oct 23;36(2):326-39.Pubmed

Markoff A, Gerke V, Bogdanova N.
Combined homology modelling and evolutionary significance evaluation of missense mutations in blood clotting factor VIII to highlight aspects of structure and function.
Haemophilia. 2009 Jul;15(4):932-41. Epub 2009 Apr 7.Pubmed

Bulk E, Sargin B, Krug U, Hascher A, Jun Y, Knop M, Kerkhoff C, Gerke V, Liersch R, Mesters RM, Hotfilder M, Marra A, Koschmieder S, Dugas M, Berdel WE, Serve H, Müller-Tidow C.
S100A2 Induces Metastasis in Non-Small Cell Lung Cancer.
Clin Cancer Res. 2009 Jan 1;15(1):22-29.Pubmed

Austermann J, Nazmi AR, Heil A, Fritz G, Kolinski M, Filipek S, Gerke V.
Generation and characterization of a novel, permanently active S100P mutant.
Biochim Biophys Acta. 2008 Dec 8. [Epub ahead of print] Pubmed

Disse J, Vitale N, Bader MF, Gerke V.
Phospholipase D1 is specifically required for regulated secretion of von-Willebrand factor from endothelial cells.
Blood. 2008 Oct 22. [Epub ahead of print] Pubmed

Goebeler V, Poeter M, Zeuschner D, Gerke V, Rescher U.
Annexin A8 Regulates Late Endosome Organization and Function.
Mol Biol Cell. 2008 Dec;19(12):5267-78. Epub 2008 Oct 15.Pubmed

Austermann J, Nazmi AR, Müller-Tidow C, Gerke V.
Characterization of the Ca2+-regulated Ezrin-S100P Interaction and Its Role in Tumor Cell Migration.
J Biol Chem. 2008 Oct 24;283(43):29331-40. Epub 2008 Aug 25. Pubmed

Rescher U, Ludwig C, Konietzko V, Kharitonenkov A, Gerke V.
Tyrosine phosphorylation of annexin A2 regulates Rho-mediated actin rearrangement and cell adhesion.
J Cell Sci. 2008 Jul 1;121(Pt 13):2177-85.Pubmed

Ebnet K, Iden S, Gerke V, Suzuki A.
Regulation of epithelial and endothelial junctions by PAR proteins
Front Biosci. 2008 May 1;13:6520-36 Pubmed

Borthwick LA, Riemen C, Goddard C, Colledge WH, Mehta A, Gerke V, Muimo R.
Defective formation of PKA/CnA-dependent annexin 2-S100A10/CFTR complex in DeltaF508 cystic fibrosis cells.
Cell Signal. 2008 Jun;20(6):1073-83. Epub 2008 Feb 5. Pubmed

Bulk E, Hascher A, Liersch R, Mesters RM, Diederichs S, Sargin B, Gerke V, Hotfilder M, Vormoor J, Berdel WE, Serve H, Müller-Tidow C.
Adjuvant therapy with small hairpin RNA interference prevents non-small cell lung cancer metastasis development in mice.
Cancer Res. 2008 Mar 15;68(6):1896-904. Pubmed

Janke M, Herrig A, Austermann J, Gerke V, Steinem C, Janshoff, A
Actin Binding of Ezrin is Activated by Specific Recognition of PIP2-Functionalized Lipid Bilayers
Biochemistry. 2008 Feb 27; [Epub ahead of print] Pubmed

Borthwick LA, Neal A, Hobson L, Gerke V, Robson L, Muimo R.
The annexin 2-S100A10 complex and its association with TRPV6 is regulated by cAMP/PKA/CnA in airway and gut epithelia.
Cell Calcium. 2008 Jan 8; [Epub ahead of print] Pubmed

van de Graaf SF, Rescher U, Hoenderop JG, Verkaart S, Bindels RJ, Gerke V.
TRPV5 is internalized via clathrin-dependent endocytosis to enter a Ca2+-controlled recycling pathway.
J Biol Chem. 2008 Feb 15;283(7):4077-86. Epub 2007 Dec 12 Pubmed

Lange C, Starrett D, Goetsch J, Gerke V, Rescher U.
Transcriptional profiling of human monocytes reveals complex changes in the expression pattern of inflammation-related genes in response to the annexin A1 derived peptide Ac1-25
J Leukoc Biol. 2007 Dec;82(6):1592-604. Epub 2007 Sep 12 Pubmed

Shpacovitch VM, Seeliger S, Huber-Lang M, Balkow S, Feld M, Hollenberg MD, Sarma VJ, Ward PA, Strey A, Gerke V, Sommerhoff CP, Vergnolle N, Steinhoff M.
Agonists of proteinase-activated receptor-2 affect transendothelial migration and apoptosis of human neutrophils.
Exp Dermatol. 2007 Oct;16(10):799-806. Pubmed

Rescher U, Gerke V.
S100A10/p11: family, friends and functions.
Pflugers Arch. 2007 Jul 19; [Epub ahead of print]Pubmed

Borthwick LA, McGaw J, Conner G, Taylor CJ, Gerke V, Mehta A, Robson L, Muimo R.
The Formation of the cAMP/PKA-dependent Annexin 2-S100A10 Complex with CFTR Regulates CFTR Channel Function.
Mol Biol Cell. 2007 Jun 20; [Epub ahead of print] Pubmed

Markoff A, Bogdanova N, Knop M, Ruffer C, Kenis H, Lux P, Reutelingsperger C, Todorov V, Dworniczak B, Horst J, Gerke V.
Annexin A5 Interacts with Polycystin-1 and Interferes with the Polycystin-1 Stimulated Recruitment of E-cadherin into Adherens Junctions.
J Mol Biol. 2007 Jun 15;369(4):954-66. Epub 2007 Mar 31. Pubmed

Bogdanova N, Horst J, Chlystun M, Croucher PJ, Nebel A, Bohring A, Todorova A, Schreiber S, Gerke V, Krawczak M, Markoff A.
A common haplotype of the annexin A5 (ANXA5) gene promoter is associated with recurrent pregnancy loss.
Hum Mol Genet. 2007 Mar 1;16(5):573-8. Epub 2007 Mar 5. Pubmed

Martin-Belmonte F, Gassama A, Datta A, Yu W, Rescher U, Gerke V, Mostov K.
PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42.
Cell. 2007 Jan 26;128(2):383-97. Pubmed

Herrig A, Janke M, Austermann J, Gerke V, Janshoff A, Steinem C.
Cooperative adsorption of ezrin on PIP2-containing membranes.
Biochemistry. 2006 Oct 31;45(43):13025-34. Pubmed 

Foulkes T, Nassar MA, Lane T, Matthews EA, Baker MD, Gerke V, Okuse K, Dickenson AH, Wood JN.
Deletion of annexin 2 light chain p11 in nociceptors causes deficits in somatosensory coding and pain behavior.
J Neurosci. 2006 Oct 11;26(41):10499-507. Pubmed

Rescher U, Goebeler V, Wilbers A, Gerke V.
Proteolytic cleavage of annexin 1 by human leukocyte elastase.
Biochim Biophys Acta. 2006 Nov;1763(11):1320-4. Epub 2006 Sep 1. Pubmed

McNeil AK, Rescher U, Gerke V, McNeil PL.
Requirement for annexin A1 in plasma membrane repair.
J Biol Chem. 2006 Nov 17;281(46):35202-7. Epub 2006 Sep 19. Pubmed 

De Seranno S, Benaud C, Assard N, Khediri S, Gerke V, Baudier J, Delphin C.
Identification of an AHNAK binding motif specific for the Annexin2/S100A10 tetramer.
J Biol Chem. 2006 Nov 17;281(46):35030-8. Epub 2006 Sep 19. Pubmed

Tatenhorst L, Rescher U, Gerke V, Paulus W.
Knockdown of annexin 2 decreases migration of human glioma cells in vitro.
Neuropathol Appl Neurobiol. 2006 Jun;32(3):271-7. Pubmed 

Goebeler V, Ruhe D, Gerke V, Rescher U.
Annexin A8 displays unique phospholipid and F-actin binding properties.
FEBS Lett. 2006 May 1;580(10):2430-4. Epub 2006 Apr 7. Pubmed

Tickenbrock L, Schwable J, Strey A, Sargin B, Hehn S, Baas M, Choudhary C, Gerke V, Berdel WE, Muller-Tidow C, Serve H.
Wnt signaling regulates transendothelial migration of monocytes.
J Leukoc Biol. 2006 Jun;79(6):1306-13. Epub 2006 Mar 24. Pubmed

Kastl K, Menke M, Luthgens E, Faiss S, Gerke V, Janshoff A, Steinem C.
Partially reversible adsorption of annexin A1 on POPC/POPS bilayers investigated by QCM measurements, SFM, and DMC simulations.
Chembiochem. 2006 Jan;7(1):106-15. Pubmed

Menke M, Gerke V, Steinem C.
Phosphatidylserine membrane domain clustering induced by annexin A2/S100A10 heterotetramer.
Biochemistry. 2005 Nov 22;44(46):15296-303. Pubmed

Markoff A, Gerke V.
Expression and functions of annexins in the kidney.
Am J Physiol Renal Physiol. 2005 Nov;289(5):F949-56. Review. Pubmed

 Hackmann K, Markoff A, Qian F, Bogdanova N, Germino GG, Pennekamp P, Dworniczak B, Horst J, Gerke V. A splice form of polycystin-2, lacking exon 7, does not interact with polycystin-1.Hum Mol Genet. 2005 Nov 1;14(21):3249-62. Epub 2005 Sep 28. Pubmed

Gerke V, Creutz CE, Moss SE.
Annexins: linking Ca2+ signalling to membrane dynamics.
Nat Rev Mol Cell Biol. 2005 Jun;6(6):449-61. Review. Pubmed

Chasserot-Golaz S, Vitale N, Umbrecht-Jenck E, Knight D, Gerke V, Bader MF.
Annexin 2 promotes the formation of lipid microdomains required for calcium-regulated exocytosis of dense-core vesicles.
Mol Biol Cell. 2005 Mar;16(3):1108-19. Epub 2005 Jan 5. Pubmed

Viemann D, Strey A, Janning A, Jurk K, Klimmek K, Vogl T, Hirono K, Ichida F, Foell D, Kehrel B, Gerke V, Sorg C, Roth J.
Myeloid-related proteins 8 and 14 induce a specific inflammatory response in human microvascular endothelial cells.
Blood. 2005 Apr 1;105(7):2955-62. Epub 2004 Dec 14. Pubmed

Chlystun M, Markoff A, Gerke V.
Structural and functional characterisation of the mouse annexin A9 promoter.
Biochim Biophys Acta. 2004 Dec 6;1742(1-3):141-9. Pubmed

Radke S, Austermann J, Russo-Marie F, Gerke V, Rescher U.
Specific association of annexin 1 with plasma membrane-resident and internalized EGF receptors mediated through the protein core domain.
FEBS Lett. 2004 Dec 3;578(1-2):95-8. Pubmed

Vogl T, Ludwig S, Goebeler M, Strey A, Thorey IS, Reichelt R, Foell D, Gerke V, Manitz MP, Nacken W, Werner S, Sorg C, Roth J.
MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes.
Blood. 2004 Dec 15;104(13):4260-8. Epub 2004 Aug 26. Pubmed

Imanishi Y, Gerke V, Palczewski K.
Retinosomes: new insights into intracellular managing of hydrophobic substances in lipid bodies.
J Cell Biol. 2004 Aug 16;166(4):447-53. Review. Pubmed

Diederichs S, Bulk E, Steffen B, Ji P, Tickenbrock L, Lang K, Zanker KS, Metzger R, Schneider PM, Gerke V, Thomas M, Berdel WE, Serve H, Muller-Tidow C.
S100 family members and trypsinogens are predictors of distant metastasis and survival in early-stage non-small cell lung cancer.
Cancer Res. 2004 Aug 15;64(16):5564-9. Pubmed

Hayes MJ, Rescher U, Gerke V, Moss SE.
Annexin-actin interactions.
Traffic. 2004 Aug;5(8):571-6. Review. Pubmed

Ruffer C, Gerke V.
The C-terminal cytoplasmic tail of claudins 1 and 5 but not its PDZ-binding motif is required for apical localization at epithelial and endothelial tight junctions.
Eur J Cell Biol. 2004 May;83(4):135-44. Pubmed

Knop M, Aareskjold E, Bode G, Gerke V.
Rab3D and annexin A2 play a role in regulated secretion of vWF, but not tPA, from endothelial cells.
EMBO J. 2004 Aug 4;23(15):2982-92. Epub 2004 Jul 15. Pubmed

Menke M, Ross M, Gerke V, Steinem C.
The molecular arrangement of membrane-bound annexin A2-S100A10 tetramer as revealed by scanning force microscopy.
Chembiochem. 2004 Jul 5;5(7):1003-6. No abstract available. Pubmed

Rescher U, Ruhe D, Ludwig C, Zobiack N, Gerke V.
Annexin 2 is a phosphatidylinositol (4,5)-bisphosphate binding protein recruited to actin assembly sites at cellular membranes.
J Cell Sci. 2004 Jul 15;117(Pt 16):3473-80. Epub 2004 Jun 29. Pubmed

Ernst S, Zobiack N, Boecker K, Gerke V, Rescher U.
Agonist-induced trafficking of the low-affinity formyl peptide receptor FPRL1. Cell Mol Life Sci. 2004 Jul;61(13):1684-92. Pubmed

Ernst S, Lange C, Wilbers A, Goebeler V, Gerke V, Rescher U.
An annexin 1 N-terminal peptide activates leukocytes by triggering different members of the formyl peptide receptor family.
J Immunol. 2004 Jun 15;172(12):7669-76. Pubmed

Rescher U, Gerke V.
Annexins--unique membrane binding proteins with diverse functions.
J Cell Sci. 2004 Jun 1;117(Pt 13):2631-9. Review. Pubmed

Shpacovitch VM, Varga G, Strey A, Gunzer M, Mooren F, Buddenkotte J, Vergnolle N, Sommerhoff CP, Grabbe S, Gerke V, Homey B, Hollenberg M, Luger TA, Steinhoff M.
Agonists of proteinase-activated receptor-2 modulate human neutrophil cytokine secretion, expression of cell adhesion molecules, and migration within 3-D collagen lattices.
J Leukoc Biol. 2004 Aug;76(2):388-98. Epub 2004 May 20. Pubmed

Ruffer C, Strey A, Janning A, Kim KS, Gerke V.
Cell-cell junctions of dermal microvascular endothelial cells contain tight and adherens junction proteins in spatial proximity.
Biochemistry. 2004 May 11;43(18):5360-9. Pubmed

Monastyrskaya K, Babiychuk EB, Schittny JC, Rescher U, Gerke V, Mannherz HG, Draeger A.
The expression levels of three raft-associated molecules in cultivated vascular cells are dependent on culture conditions.
Cell Mol Life Sci. 2003 Dec;60(12):2702-9. Pubmed

Jacob R, Heine M, Eikemeyer J, Frerker N, Zimmer KP, Rescher U, Gerke V, Naim HY.
Annexin II is required for apical transport in polarized epithelial cells. J Biol Chem. 2004 Jan 30;279(5):3680-4. Epub 2003 Dec 11. Pubmed

Zobiack N, Rescher U, Ludwig C, Zeuschner D, Gerke V.
The annexin 2/S100A10 complex controls the distribution of transferrin receptor-containing recycling endosomes.
Mol Biol Cell. 2003 Dec;14(12):4896-908. Epub 2003 Sep 17. Pubmed

Goebeler V, Ruhe D, Gerke V, Rescher U.
Atypical properties displayed by annexin A9, a novel member of the annexin family of Ca(2+) and lipid binding proteins.
FEBS Lett. 2003 Jul 10;546(2-3):359-64. Pubmed

Koltzscher M, Neumann C, Konig S, Gerke V.
Ca2+-dependent binding and activation of dormant ezrin by dimeric S100P. Mol Biol Cell. 2003 Jun;14(6):2372-84.
Pubmed

van de Graaf SF, Hoenderop JG, Gkika D, Lamers D, Prenen J, Rescher U, Gerke V, Staub O, Nilius B, Bindels RJ. Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex.EMBO J. 2003 Apr 1;22(7):1478-87. Pubmed

Ross M, Gerke V, Steinem C.
Membrane composition affects the reversibility of annexin A2t binding to solid supported membranes: a QCM study.
Biochemistry. 2003 Mar 18;42(10):3131-41. Pubmed

Knop M, Gerke V.
Ca2+ -regulated secretion of tissue-type plasminogen activator and von Willebrand factor in human endothelial cells.
Biochim Biophys Acta. 2002 Nov 4;1600(1-2):162-7. Pubmed PMID: 12445472 [PubMed - indexed for MEDLINE] 

Kastl K, Ross M, Gerke V, Steinem C.
Kinetics and thermodynamics of annexin A1 binding to solid-supported membranes: a QCM study.
Biochemistry. 2002 Aug 6;41(31):10087-94. Pubmed

Rescher U, Danielczyk A, Markoff A, Gerke V.
Functional activation of the formyl peptide receptor by a new endogenous ligand in human lung A549 cells.
J Immunol. 2002 Aug 1;169(3):1500-4. Pubmed

Strey A, Janning A, Barth H, Gerke V.
Endothelial Rho signaling is required for monocyte transendothelial migration.
FEBS Lett. 2002 Apr 24;517(1-3):261-6. Pubmed

Gerke V, Moss SE.
Annexins: from structure to function.
Physiol Rev. 2002 Apr;82(2):331-71. Review. Pubmed

Janshoff A, Ross M, Gerke V, Steinem C.
Visualization of annexin I binding to calcium-induced phosphatidylserine domains.
Chembiochem. 2001 Aug 3;2(7-8):587-90. No abstract available. Pubmed

Zobiack N, Rescher U, Laarmann S, Michgehl S, Schmidt MA, Gerke V.
Cell-surface attachment of pedestal-forming enteropathogenic E. coli induces a clustering of raft components and a recruitment of annexin 2.
J Cell Sci. 2002 Jan 1;115(Pt 1):91-8. Pubmed

Zeuschner D, Stoorvogel W, Gerke V.
Association of annexin 2 with recycling endosomes requires either calcium- or cholesterol-stabilized membrane domains.
Eur J Cell Biol. 2001 Aug;80(8):499-507. Pubmed

Gerke V.
Annexins And Membrane Organisation In The Endocytic Pathway.
Cell Mol Biol Lett. 2001;6(2):204. No abstract available. Pubmed

Merrifield CJ, Rescher U, Almers W, Proust J, Gerke V, Sechi AS, Moss SE.
Annexin 2 has an essential role in actin-based macropinocytic rocketing.
Curr Biol. 2001 Jul 24;11(14):1136-41. Pubmed

Zobiack N, Gerke V, Rescher U.
Complex formation and submembranous localization of annexin 2 and S100A10 in live HepG2 cells.
FEBS Lett. 2001 Jul 6;500(3):137-40. Pubmed

Bogdanova N, Markoff A, Gerke V, McCluskey M, Horst J, Dworniczak B.
Homologues to the first gene for autosomal dominant polycystic kidney disease
are pseudogenes. Genomics. 2001 Jun 15;74(3):333-41. Pubmed

Kielbassa-Schnepp K, Strey A, Janning A, Missiaen L, Nilius B, Gerke V.
Endothelial intracellular Ca2+ release following monocyte adhesion is required
for the transendothelial migration of monocytes. Cell Calcium. 2001 Jul;30(1):29-40. Pubmed

Rosengarth A, Rosgen J, Hinz HJ, Gerke V.
Folding energetics of ligand binding proteins II. Cooperative binding of Ca2+ to annexin I.
J Mol Biol. 2001 Mar 2;306(4):825-35. Pubmed

Rosengarth A, Gerke V, Luecke H.
X-ray structure of full-length annexin 1 and implications for membrane aggregation.
J Mol Biol. 2001 Feb 23;306(3):489-98. Pubmed

Konig J, Gerke V.
Modes of annexin-membrane interactions analyzed by employing chimeric annexin proteins.
Biochim Biophys Acta. 2000 Dec 20;1498(2-3):174-80. Pubmed

Russo-Marie F, Donato R, Gerke V V, Haiech J, Heizmann CW, Pochet R.
Preface. . 2000 Dec 20;1498(2-3):81. No abstract available. Pubmed

Lewit-Bentley A, Rety S, Sopkova-de Oliveira Santos J, Gerke V.
S100-annexin complexes: some insights from structural studies.
Cell Biol Int. 2000;24(11):799-802. Pubmed

Rescher U, Zobiack N, Gerke V.
Intact Ca(2+)-binding sites are required for targeting of annexin 1 to endosomal membranes in living HeLa cells.
J Cell Sci. 2000 Nov;113 ( Pt 22):3931-8. Pubmed

Muimo R, Hornickova Z, Riemen CE, Gerke V, Matthews H, Mehta A.
Histidine phosphorylation of annexin I in airway epithelia.
J Biol Chem. 2000 Nov 24;275(47):36632-6. Pubmed

Koltzscher M, Gerke V.
Identification of hydrophobic amino acid residues involved in the formation of S100P homodimers in vivo.
Biochemistry. 2000 Aug 8;39(31):9533-9. Pubmed

Lang F, Klingel K, Wagner CA, Stegen C, Warntges S, Friedrich B, Lanzendorfer M, Melzig J, Moschen I, Steuer S, Waldegger S, Sauter M, Paulmichl M, Gerke V, Risler T, Gamba G, Capasso G, Kandolf R, Hebert SC, Massry SG, Broer S.
Deranged transcriptional regulation of cell-volume-sensitive kinase hSGK in diabetic nephropathy.
Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):8157-62. Pubmed

Walther A, Riehemann K, Gerke V.
A novel ligand of the formyl peptide receptor: annexin I regulates neutrophil extravasation by interacting with the FPR.
Mol Cell. 2000 May;5(5):831-40. Pubmed

Rety S, Osterloh D, Arie JP, Tabaries S, Seeman J, Russo-Marie F, Gerke V, Lewit-Bentley A.
Structural basis of the Ca(2+)-dependent association between S100C (S100A11) and its target, the N-terminal part of annexin I.
Structure. 2000 Feb 15;8(2):175-84. Pubmed