Program
| Thursday, March 10 | |
| 10.00 - 13.00 | Registration and Lunch |
| 13.00 - 14.00 | Plenary Lecture Chair: Jörg Gromoll, Münster |
| X-inactivation dynamics - Joost Gribnau, The Netherlands | |
| 14.00 - 15.30 | X-Chromosome Chair: Alberto Ferlin, Padua; Gabriel Marais, Lyon |
| Increasing prenatal diagnoses of KS: controversies in clinical counselling - Frank Tüttelmann, Germany | |
| Epigenetic signatures in the brain of KS patients - Joana Viana, UK | |
| X-chromosome regulation - Christine Disteche, USA | |
| 15.30 - 16:00 | Coffee |
| 16.00 - 17.30 | Animal models on sex chromosomal aneuploidies Chairs: Stefan Schlatt, Münster; Liborio Stuppia, Chieti |
| The Sex Chromosome Trisomy mouse model of XXY and XYY - Art Arnold, USA | |
| Neuroimaging Genomics of Sex Chromosome Aneuploidy - Armin Raznahan, USA | |
| The XXY-mouse models and their clinical counterpart - Joachim Wistuba, Germany | |
| 17.30 - 19.00 | Selected oral communications |
| Fertility preservation in Klinefelter boys: an update after 6 years’ experience - Dorien Van Saen, Belgium | |
| Hypothetical higher setting of hypothalamus pituitary testis axis in infants with non-mosaic Klinefelter Syndrome- Simona Granato, Italy | |
| A Multidisciplinary Model of Early Fertility Preservation in Klinefelter Patients: Description of a Program - Hooman Sadri-Ardekani, USA | |
| Expansion of the language phenotype in Klinefelter syndrome and children with XXYY - Jacqueline Frazier, USA | |
| Disturbed testicular vascularization in 41, XXY* mice: a functional analysis using contrast enhanced ultrasound - Oliver S. Damm, Germany | |
| Transcriptome analysis of testis tissue from pre-pubertal Klinefelter boys - Sofia Boeg Winge, Denmark | |
| Klinefelter syndrome co-morbidities induced by increased gene dosage and altered interactome activity - Kirstine Belling, Denmark | |
| Effects of long-term treatment with testosterone undecanoate injections (TU) in patients diagnosed with Klinefelter’s syndrome (KS) following detection of osteoporosis. Farid Saad, Germany | |
| 19.30 - 22.00 | Welcome Reception |
| Friday, March 11 | |
| 9.00 - 10.30 | Disorders of sexual development - DSD Chairs: Annette Richter-Unruh, Münster; Armin Raznahan, Bethesda |
| The evolution of dosage compensation and the implications for human X aneuploidy syndromes - Gabriel Marais, France | |
| Turner syndrome – the other side of the coin - Claus Gravholt, Denmark | |
| The European COST Initiative on DSD - Olaf Hiort, Germany | |
| 10.30 - 11.00 | Coffee |
| 11.00 - 12.30 | Metabolic and cardiovascular risks Chairs: Anders Juul, Copenhagen; Eberhard Nieschlag, Münster |
| Cardiovascular risks - Michael Zitzmann, Germany | |
| Metabolic risks - Anders Bojesen, Denmark | |
| Osteoporosis risks - Alberto Ferlin, Italy | |
| 12.30 - 13.30 | Lunch |
| 13.30 - 14.30 | Posterpresentation |
| 14.30 - 16.00 | Transition care Chairs: Vicenco Rochira, Modena; Herve Lejeune, Lyon |
| Testicular changes during transition - Niels Skakkebæk, Denmark | |
| Testosterone replacement in infants and young children - Carole Samango-Sprouse, USA | |
| Transition to adult care for adolescents/emerging adults with Klinefelter syndrome: Much more than just Testosterone - Alan Rogol, USA | |
| 16.00 - 16.30 | Coffee |
| 16.30 - 18.00 | Neuropsychology and cognition Chairs: Georg Romer, Münster; Sophie Van Rhjin, Leiden |
| Neuropsychology and socioeconomic aspects - Anne Skakkebæk, Denmark | |
| Social cognition and underlying cognitive mechanisms - Hanna Swaab, Netherlands | |
| Behavioral and social phenotypes in boys with 47,XYY syndrome or 47,XXY Klinefelter syndrome - Nicole Tartaglia, USA | |
| 19.00 - 22.00 | Dinner |
| Saturday, March 12 | |
| 9.00 - 10.30 | Spermatogenesis and fertility preservation Chairs: Ewa Raipert-de Meyts, Copenhagen; Dorien Van Saen, Bruessels |
| Transcriptome of KS testis - Liborio Stuppia, Italy | |
| Fertility preservation in young and adult KS patients - Sabine Kliesch, Gemany | |
| Klinefelter syndrome and TESE-ICSI - Hervé Lejeune, France | |
| 10.30 - 11.00 | Coffee |
| 11.00 - 12.30 | Optimized treatment for hypogonadism Chairs: Fred Wu, Manchester; Carole Samango-Sprouse, Washington |
| XXY Klinefelter syndrome: clinical characteristics and age-specific recommendations for medical management - Anders Juul, Denmark | |
| hCG and steroidogenesis - Manuela Simoni, Italy | |
| dsd-LIFE: QoL, satisfaction with care and needs of adolescents and men with Klinefelter syndrome - Birgit Köhler, Germany | |
| 12.30 - 13.30 | Round table: Klinefelter syndrome current management and challenges |
| Eberhard Nieschlag, Germany, plus others | |
| 13.30 - 15:00 | Lunch and Adjourn |