

Clinical Trials in Ophthalmology (CTO)
Clinical trials help develop new medical treatments and improve existing ones. Drugs and new treatments are tested for their efficacy and safety. The Department of Ophthalmology participates in numerous national and international multicenter studies. This is the only way we can guarantee you state-of-the-art patient care.
By participating in a clinical trial, we can offer you innovative treatment options that are not yet available in routine care.
If you are interested in participating in a study, please contact our study team!
Clarity Study
Clinical trial for patients with active, non-infectious, intermediate, posterior or pan-uveitis. Oral administration of brepocitinib
REVISION Study
Clinical trial on early lysis in central retinal artery occlusion (inclusion in the treatment arm possible up to 4.5 hours after symptom onset)
SAMSARA trial
Implantation of a mini-telescope in patients with geographic atrophy who have not yet undergone cataract surgery
SIENNA trial
Clinical trial for patients with geographic atrophy without foveal involvement; subcutaneous injections of pozelimab + cemdisiran versus cemdisiran monotherapy versus placebo
UplighTED trial
Clinical trial for patients with endocrine orbitopathy; subcutaneous injection of efgartigimod; initial diagnosis <12 months
CCS Register
Prospective data collection on patients with central serous chorioretinopathy
LHON Register
Non-interventional study / LHON Register for LHON patients with and without treatment
ROP Register
Database for recording patients with retinopathy of prematurity
Fungal Keratitis Register
German Fungal Keratitis Register. Prospective collection of clinical and diagnostic data
Acanthamoeba Register
German Acanthamoeba Keratitis Register. Retrospective and prospective collection of clinical and diagnostic data
TOFU Register
Register of treatment discharge options for non-infectious uveitis
AIM trial (recruitment closed)
Clinical trial to slow the progression of myopia in children aged 8–12. Study drug: low-dose atropine
ASCENT trial (recruitment closed)
Clinical trial for patients with nAMD. Subretinal injection of RGX-314. Initial diagnosis < 4 years
HONU trial (recruitment closed)
Observational study on the progression of intermediate age-related macular degeneration
HORIZON trial (recruitment closed)
Clinical trial for endocrine orbitopathy. Infusion of teprotumumab

The Department of Ophthalmology at the University Hospital Münster is an EVICR.net certified center.