Principal Investigator


Prof. Dr. Christos Gatsogiannis, Principal Investigator

Address: Center for Soft Nanoscience (SoN) 

Busso-Peus-Str. 10, D-48149 Münster

Office: 110.001

Phone: +49 251 83 34411

E-mail: Christos.gatsogiannis@uni-muenster.de

Twitter: @gatsogia

Curriculum Vitae

 

 


Elisa Schulze Averbeck, Assistant

Address: Center for Soft Nanoscience (SoN) 

Busso-Peus-Str. 10, 48149 Münser 

Office: 110.002

Phone: +49 251 83 34444

E-mail: Gatsogiannis.Office@uni-muenster.de

Elisa previously worked in the events and insurance industry. She is very excited to dive into the new, highly interesting work environment and to work with a young, motivated and international team in the modern Center for Soft Nanoscience.


Scientific Team


©Karthik Kalyankumar
©Karthik Kalyankumar

Dr. Alexander Neuhaus, Facility Manager cryoEM SoN

Address: Center for Soft Nanoscience (SoN) 

Busso-Peus-Str. 10, D-48149 Münster 

Office: 100.018

Phone: +49 251 83 34420

E-mail: alexander.neuhaus@uni-muenster.de

Alexander studied biochemistry at the Ruhr University Bochum. He obtained both his master’s degree and PhD in the group of Prof. Ralf Erdmann where he studied peroxisomal biogenesis. In 2013 he joined the group of Prof. Werner Kühlbrandt at the MPI of Biophysics in Frankfurt (Main). There he learned the technique of electron microscopy and cryo-EM. He analysed peroxisomal proteins and pore-forming toxins. He joined the group of Dr. Vicki Gold at the University of Exeter (UK) in 2018 to study type IV pili using cryo-EM. Since 2022 he is the facility manager for the cryo-EM infrastructure und application specialist for cryo-EM at the Center for Soft Nanoscience. Together with Anja Blanque he ensures the optimal condition of the equipment and provides training and support for users of the facility.


Dr. rer. nat Anja Blanque, Application Specialist  cryo-EM SoN

Address: Center for Soft Nanoscience (SoN)

Busso-Peus-Str. 10, D-48149 Münster 

Office: 100.018

Phone: +49 251 83 34407

E-mail: blanquea@uni-muenster.de

Since graduating as a BTA in 1994, Anja has worked in various institutes at the University of Osnabrück and the University Hospital Münster, most recently with Prof. Schillers and Prof. Linke. During this time, she used her experience in biochemistry as well as light-, confocal- and atomic force microscopy to support cancer- and muscle research. Anja also gained a diploma in biology at the University of Osnabrück and completed her doctorate in 2015 in the group of Prof. Missler at the Institute for Anatomy and Molecular Neurobiology in Münster, implementing conventional and spectroscopic EM-methods. As facility staff she uses her knowledge of conventional EM and modern cryo-techniques to ensure the smooth running of our cryo-EM facility and train new users together with the facility manager.

 


©Karthik Kalyankumar

Dr. Jorgaq Pata, Post-Doc

Adress: Center for Soft Nanoscience (SoN) 

Busso-Peus-Str. 10, D-48149 Münster 

Office: 100.020

Phone: +49 251 83 34444

E-mail: pata@uni-muenster.de

Jorgaq obtained both his Bachelor and Master’s degree at Claude Bernard Lyon 1 University, studying biochemistry and structural biology. During his PhD thesis under the supervision of Dr. Pierre Falson, he studied the drug resistance of pathogenic fungi mediated by the expression of ABC transporters. There, he learned how to handle membrane proteins and investigate their function and their structure using cryoEM, and elucidated different high-resolution structures and the conformational landscape of the target proteins. During his post-doc, he will work on structural studies of the yeast peroxisome using cryo-electron tomography.


©Karthik Kalyankumar

Dr. Hengxi Zhang, Post-Doc (co-supervised with Prof. Strünker)

Address: Center for Soft Nanoscience (SoN) 

Busso-Peus-Str. 10, D-48149 Münster 

Office: 100.020

Phone: 0251 83 34444

E-mail: zhang@uni-muenster.de

Hengxi Zhang started her research career in 2014 at Shandong University, China, where she investigated the substrate-binding specificity and promiscuity of enzymes by analyzing the active-site architecture. After receiving her master's degree in microbiology in 2017, Hengxi Zhang went on to pursue her Ph.D. degree at the Freie Universität Berlin and the Max Planck Institute for Colloids and Interfaces in Germany. During her PhD, she accumulated extensive background knowledge in structural biology and pharmacology and learned how to utilize protein-based nuclear magnetic resonance (NMR) and other biophysical techniques to study protein structure, protein-drug interactions, and drug screening. She received her PhD from the Universität Wien with a thesis on the identification of allosteric modulators and investigations into the allosteric mechanism of the C-type lectins DC-SIGN and Langerin.  After completing her PhD, Hengxi went to the Chinese University of Hong Kong (Shenzhen) to learn how to express membrane proteins using mammalian and insect cells. Hengxi joined us on 1 April 2024 and will carry out in situ structural studies of human sperm protein complexes using cryo-electron tomography.


©Karthik Kalyankumar

Dr. rer. nat. Björn Udo Klink, Senior Scientist

Address: Center for Soft Nanoscience (SoN) 

Busso-Peus-Str. 10, D-48149 Münster 

Office: 110.018.2

Phone: +49 251 83 34465

E-mail: Bjoern.Klink@uni-muenster.de

Björn's scientific career began in 2001 at the Max Planck Institute in Dortmund, where he first learned and applied biophysical methods in his diploma thesis and then combined them with X-ray crystallography in his doctoral thesis. His growing interest in structural biology led him to six institutes in Germany, England and the USA before he joined Prof. Dr. Stefan Raunser's group back at the Max Planck Institute in Dortmund in 2013. There Björn learned the technique of electron microscopy. With his acquired practical experience in cryo-EM, crystallographic and biophysical techniques, he has solved several novel structures. His great passion includes understanding the function and architecture of large hetero-oligomeric protein complexes.

 


©Karthik Kalyankumar

Karthik Subramaniam Kalyankumar (M.Sc.), Doctoral student

Adresse: Center for Soft Nanoscience (SoN) 

Busso-Peus-Str. 1, 48149 Münster 

Office: 110.018.2

Telefon: +49 251 83 34465

E-mail address: kalyanku@uni-muenster.de

Karthik Subramaniam obtained both his bachelor's and master's degree from the Sri Sathya Sai Institute of Higher Learning (Deemed to be University) in India. During his master’s thesis, Karthik worked in the group of Dr.S.Venkatesh to study about the Gene-Amyloid relationships in Huntington’s Disease (a Neurodegenerative Disease) using Yeast as a Model Organism. Karthik’s work here will focus on the structural analysis of the latrotoxins, neurotoxins produced by the black widow spider.


©Karthik Kalyankumar

Maximilian Rüttermann (M.Sc.), Doctoral student

Address: Center for Soft Nanoscience (SoN) 

Busso-Peus-Str. 10, D-48149 Münster 

Office: 110.018.2

Phone: +49 251 83 34425

E-mail address: Maximilian.Ruettermann@uni-muenster.de

Twitter: @RuetterM

Maximilian studied biochemistry at the Ruhr University Bochum. He carried out his Bachelor's thesis at the Center for Solvation Science (ZEMOS) in the group of Prof. Martina Havenith-Newen. In doing so, he dealt with the fundamental solvation dynamics within model membranes, similar to those of biological cells. For his Master thesis, Maximilian joined the labs of Prof. Thomas Günther-Pomorski and Prof. Ralf Erdmann on the lipid flippase activity of peroxisomal membrane proteins.

 


©Karthik Kalyankumar

Athina Drakonaki (M.Sc) , Doctoral student

Address: Center for Soft Nanoscience (SoN) 

Busso-Peus-Str. 10, D-48149 Münster 

Office: 100.017

Phone: +49 251 83 34419

E-mail address: drakonak@uni-muenster.de

Athina obtained both her Bachelor's and Master's degrees from the University of Crete in Greece. She is a biochemist with a background in metabolomics analysis. During her Master's thesis, Athina worked part-time in Prof. Hartmut Michel's group at the MPI in Frankfurt am Main. In Frankfurt, her interest in structural biology grew, which led her to join our team as a PhD student. Athina's work will focus on the structural analysis of the p97 complex and its associated cofactors, which she is carrying out as part of the Collaborative Research Centre 1430 based at the University of Duisburg Essen.

 


©Karthik Kalyankumar

Cole Bourque (M.Sc) , Doctoral student

Address: Center for Soft Nanoscience (SoN) 

Busso-Peus-Str. 10, D-48149 Münster 

Office: 110.018.2

Phone: +49 251 83 34425

E-mail: Cole.Bourque@uni-muenster.de

At Colorado State University in the United States, Cole earned his bachelor's degree in zoology. During his studies, he discovered his enthusiasm for biochemistry. So, Cole began his master's studies at the Ruhr University in Bochum, Germany, with a focus on molecular medicine. Cole completed his master's thesis in the laboratory of Prof. Dr. Gatsogiannis, investigating the structure of the yeast protein complex Dam1 and its associated proteins Bim1 and Bik1, which are crucial for the process of mitosis. Currently, Cole is continuing the work begun during his Master's thesis as a doctoral student with Prof. Dr. Gatsogiannis. The project is part of the Collaborative Research Centre 1430 at the University of Duisburg-Essen and focuses on continuing his work on the Dam1 complex and its associated proteins Bim1 and Bik1 to better understand their functions and interaction mechanisms.

 


©Karthik Kalyankumar

Simone Neuwirth, Laboratory Technician

Address: Center for Soft Nanoscience (SoN)

Busso-Peus-Str. 10, D-48149 Münster 

Office: 110.040

Phone: +49 251 83 34484

E-mail address: simone.neuwirth@uni-muenster.de

Simone successfully completed her training as a chemical laboratory technician at a large biotechnology company in 2018. She gained her first professional experience as a Research Development Technician in in-vitro test development for infectious serology. Looking for a new challenge and further development, she landed with us and supports our team as a technical, very motivated employee. In addition to her work in the lab, she is doing a distance learning course in molecular biology.


George Broutzakis (M.Sc), Guest Doctoral student

Center for Soft Nanoscience (SoN) 

Busso-Peus-Str. 10, D-48149 Münster

Office: 110.018.2

Phone: +49 251 83 34425

E-mail address: broutzakis@uni-muenster.de

George received his Bachelor’s degree in Biology from the University of Athens, with an emphasis on Molecular Biology and Genetics. During his undergraduate thesis, George developed a novel system to identify small cyclic peptides that can salvage misfolded membrane proteins in the lab of Dr. G. Skretas at the National Hellenic Research Foundation. He is currently pursuing a PhD degree in the laboratory of Prof. G. Diallinas in the University of Athens, where he studies membrane protein trafficking and structure-function relationships. To aid in this, he is currently visiting Prof. Gatsogiannis’s lab to learn Cryo-Electronic Microscopy and apply ​it to one of the best-studied eukaryotic transporters, UapA.


©Karthik Kalyankumar

Eda Şamiloğlu Tengirşek, Fellow

Center for Soft Nanoscience (SoN) 

Busso-Peus-Str. 10, D-48149 Münster

Office: 110.018.2

E-mail address: amilolut@uni-muenster.de

Eda received her bachelor’s degree in molecular biology and genetics from the University of Istanbul. For her master’s thesis, she worked in the Computational Structural Biology group at the Izmir Biomedicine and Genome Center (IBG). Her master's research allowed her to rethink cell biology from a three-dimensional perspective, and she became particularly interested in CryoEM. She currently visiting Prof. Gatsogiannis’s lab as a pre-doctoral intern. She will work on establishing a CryoET image processing workflow during her internship.


©Karthik Kalyankumar

Dionysios Ermis Geladas, ERASMUS Student

Center for Soft Nanoscience (SoN) 

Busso-Peus-Str. 10, D-48149 Münster

Office: 110.018.2

E-mail address: geladas@uni-muenster.de

Ermis completed his bachelor's degree in the Department of Chemistry at the University of Crete. During his bachelor's thesis, he studied the biopolymer PHB. Currently, Ermis is studying in the laboratory of Prof. Dr. G. Tsiotis at the University of Crete. He is trying to characterize the structure and composition of PHB granules in Pseudomonas sp. phDV1. To achieve this goal, Ermis joined us as an Erasmus student to learn and apply the method of cryo-electron microscopy.


Mattis Bollmann , Student

Address: Center for Soft Nanoscience (SoN) 

Busso-Peus-Str. 10, 48149 Münster 

Office: 110.040

 

Mattis received his Bachelor's degree in Biochemistry from the Georg-August University Göttingen. During his Bachelor's thesis in the field of biomolecular chemistry at the Department of Prof. Dr. Steinem he contributed to the "Living Foam"-Project which addresses the development of artificial tissue structures. Currently Mattis is enrolled at the Heinrich-Heine University for his Masters degree in Molecular biomedicine. During his Internship and Master's thesis at the lab of Prof. Dr. Gatsogiannis he aims to learn Cryo-EM Microscopy and elucidate the structure of a known peroxisomal protein.

 

 

 

 

Alumni

  • Dr. Minghao Chen, (PhD), University of California, Berkeley, Hurley lab
  • Pascal Lill (PhD), Max-Planck Institute for Molecular Physiology Dortmund, 2016 - 2021, current address: Postdoc, Wyss Institute for Biological Inspired Engineering, Harvard Medical School, Boston
  • Bastian Möllers (M.Sc in Medical Biology), University of Duisburg-Essen, 2021, current address: PHD Student, University of Duisburg-Essen
  • Michelle Koci (M.Sc. in Biochemistry), Ruhr-University Bochum, 2020, current address: PHD Student, University of Duisburg-Essen
  • Alwin Chew, EMBO Guest PHD Student, 2020, current address: Nanyang Technological University, Singapore
  • Lena Engelhard (M.Sc. in Biochemistry), Ruhr-University Bochum, 2020, current address: PHD Student, TU Dortmund
  • Dimitrios Vismpas  (M.Sc. in Proteinbiotechnology), University Crete, 2020, current address: PHD Student, Utrecht University
  • Prof. Takashi Matsui, Gastwissenschaftler, Tohoku University Japan, 2019
  • Lydia Borgelt (M.Sc. in Chemische Biologie, Technische University Dortmund, 2018, current address: PHD Student, Max Planck Institute of Molecular Physiology, Dortmund
  • Jonas Miehling, Praktikant, 2018, current address: PHD Student, MRC-LMB
  • Lydia Borgelt (M.Sc. in Chemical Biology), TU Dortmund, 2018, current address: PHD Student, Max Planck Institute of Molecular Physiology, Dortmund
  • Justina Stark (M.Sc. in Chemical Biology), TU Dortmund, 2018, current address: PHD Student, Max Planck Institute Molecular Cell Biology and Genetics, Dresden