International cooperative randomized trial of the SIOPE Brain Tumour Group for the treatment of newly diagnosed and recurrent

high-grade gliomas in children, adolescents, and young adults

Beteiligte Wissenschaftler und Funktion

Statistische Planung und statistische Auswertung
Univ.-Prof. Dr. rer. nat. et med. habil. Andreas Faldum
Dr. rer. nat. Robert Kwiecien

Studienleitung
Prof. Dr. med. Michael Karremann, University Medical Centre Mannheim (UMM)

Förderung
Deutsche Kinderkrebsstiftung

Ziel der Studie
-The trial aims to investigate and to improve survival / event-free-survival / post progression or relapse survival / rate of Metastasis at first progression during 2 years in patients with histologically proven pediatric diffuse HGG CNS WHO grade 3 and 4, radiologically proven DIPG, and GC, under several treatments dependent on patients disease characteristics.