Beel S, Kolloch L, Apken LH, Jürgens L, Bolle A, Sudhof N, Ghosh S, Wardelmann E, Meisterernst M, Steinestel K, Oeckinghaus A. κB-Ras and Ral GTPases regulate acinar to ductal metaplasia during pancreatic adenocarcinoma development and pancreatitis. 2020; Nat. Commun. 11:3409

Heiss G, Ploetz E, Voith von Voithenberg L, Viswanathan R, Glaser S, Schluesche P, Madhira S, Meisterernst M, Auble DT, Lamb DC. Conformational changes and catalytic inefficiency associated with Mot1-mediated TBP-DNA dissociation. 2019; Nucleic Acids Res. 47:2793-2806

Zarrabi N, Schluesche P, Meisterernst M, Börsch M, Lamb DC. Analyzing the Dynamics of Single TBP-DNA-NC2 Complexes Using Hidden Markov Models. 2018; Biophys J. 115:2310-2326

Leal A, Bogantes-Ledezma S, Ekici AB, Uebe S, Thiel CT, Sticht H, Berghoff M, Berghoff C, Morera B, Meisterernst M, Reis A. The polynucleotide kinase 3'-phosphatase gene (PNKP) is involved in Charcot-Marie-Tooth disease (CMT2B2) previously related to MED25. 2018; Neurogenetics 19:215-225

Albert TK, Antrecht C, Kremmer E, Meisterernst M. The establishment of a hyperactive structure allows the tumour suppressor protein p53 to function through P-TEFb during limited CDK9 kinase inhibition. 2016; PLoS One 11:e0146648

Kelso TW, Baumgart K, Eickhoff J, Albert T, Antrecht C, Lemcke S, Klebl B, Meisterernst M. Cyclin-dependent kinase 7 controls mRNA synthesis by affecting stability of preinitiation complexes, leading to altered gene expression, cell cycle progression, and survival of tumor cells. 2014; Mol. Cell. Biol. 34:3675-3688

Kerl K, Moreno N, Holsten T, Ahlfeld J, Mertins J, Hotfilder M, Kool M, Bartelheim K, Schleicher S, Handgretinger R, Schüller U, Meisterernst M, Frühwald MC. Arsenic trioxide inhibits tumor cell growth in malignant rhabdoid tumors in vitro and in vivo by targeting overexpressed Gli1. 2014; Int. J. Cancer 135:989-995

Albert TK, Rigault C, Eickhoff J, Baumgart K, Antrecht C, Klebl B, Mittler G, Meisterernst M. Characterization of molecular and cellular functions of the cyclin-dependent kinase CDK9 using a novel specific inhibitor. 2014; Br. J. Pharmacol. 117:55-68

Kerl K, Holsten T, Frühwald MC. Rhabdoid tumors: clinical approaches and molecular targets for innovative therapy. 2013; Pediatr. Hematol. Oncol. 30:587-604

Kerl K, Ries D, Unland R, Borchert C, Moreno N, Hasselblatt M, Jürgens H, Kool M, Görlich D, Eveslage M, Jung M, Meisterernst M, Frühwald M. The histone deacetylase inhibitor SAHA acts in synergism with fenretinide and doxorubicin to control growth of rhabdoid tumor cells. 2013; BMC Cancer 13:286-296

Ries D, Meisterernst M. Control of gene transcription by Mediator in chromatin. 2011; Semin. Cell. Dev. Biol. 22:735-740

Vojnic E, Mourao A, Seizl M, Simon B, Wenzeck L, Larivière L, Baumli S, Baumgart K, Meisterernst M, Sattler M, Cramer P. Structure and VP16 binding of the Mediator Med25 activator interaction domain. 2011; Nat. Struct. Mol. Biol. 18:404-409

Koch F, Fenouil R, Gut M, Cauchy P, Albert TK, Zacarias-Cabeza J, Spicuglia S, de la Chapelle AL, Heidemann M, Hintermair C, Eick D, Gut I, Ferrier P, Andrau JC. Transcription initiation platforms and GTF recruitment at tissue-specific enahncers and promoters. 2011; Nat. Stuct. Mol. Biol. 18:956-963

Albert TK, Grote K, Boeing S, Meisterernst M. Basal core promoters controll the equilibrium between negative cofactor 2 and preinitiation complexesin human cells. 2010; GenomeBiol. 11:R33

Roupelieva M, Griffiths SJ, Kremmer E, Meisterernst M, Viejo Borbolla A, Schulz T, Haas J. Kaposi's Sarcoma associated Herpesvirus (KSHV) Lana-1 is a major activator of the serum response element (SRE) and MAPK pathways via interactions with the Mediator complex. 2010; J. Gen. Virol. 91:1138-1149

Böing S, Rigault C, Heidemann M, Eick D, Meisterernst M. RNA polymerase II C-terminal heptarepeat domain Ser-7 phosphorylation is established in a mediato-dependent fashion. 2010; J. Biol. Chem. 285:188-196

Leal A, Huehne K, Bauer F, Sticht H, Berger P, Suter U, Morera B, Del Valle G, Lupski JR, Ekici A, Pasutto F, Endele S, Barrantes R, Berghoff C, Berghoff M, Neundörfer B, Heuss D, Dorn T, Young P, Santolin L, Uhlmann T, Meisterernst M, Sereda M, Zu Horste GM, Nave KA, Reis A, Rautenstrauss B. Identification of the variant Ala335Val of MED25 as responsible for CMT2B2: molecular data, functional studies of the SH3 recognition motif and correlation between wild-type MED25 and PMP22 RNA levels in CMT1A animal models. 2009; Neurogenetics 10:275-287

Kahle J, Piaia E, Neimanis S, Meisterernst M, Doenecke D. Regulation of nuclear import and export of negative cofactor 2. 2009; J. Biol. Chem. 284:9382-9393

Mortusewicz O, Roth W, Li N, Cardoso MC, Meisterernst M*, and Leonhardt H*. Recruitment of RNA Polymerase II cofactor PC4 to DNA repair sites. 2008; J. Cell Biol. 183:769-776 * equal contributions

Chapman RD, Heidemann M, Albert TK, Mailahmmer R, Flatley A, Meisterernst M, Kremmer E, Eick D. Transcribing RNA polymerase II is phosphorylated at CTD serine-7. 2007; Science 318:1780-1782

Schlüsche P, Stelzer G, Piaia E, Lamb D, Meisterernst M. RNA polymerase II cofactor NC2 mobilizes TBP on gene promoter regions. 2007; Nat. Struc. Mol. Biol. 14:1196-1201

Albert T, Grote K, Böing S, Stelzer G, Schepers A, Meisterernst M. Global distribution of negative cofactor 2 subunit alpha on human promoters. 2007; Proc. Natl. Acad. Sci. USA 104:10000-10005

Uhlmann T, Böing S, Lehmbacher, Meisterernst M. VP16 activation domain establishes an active Mediator lacking CDK8 in vivo. 2007; J. Biol. Chem. 282:2163-2173

Santolin L, Meisterernst M. TFII-IDelta and TFII-Ibeta: unequal brothers fostering cellular proliferation. 2006; Mol. Cell. 24:169-171 Review.

Blazek E, Meisterernst M. A functional proteomics approach for the detection of nuclear proteins based on derepressed importin alpha. 2006; Proteomics 6:2070-2078

Gilfillan S, Stelzer G, Piaia E, Hofmann MG, Meisterernst M. Efficient binding of NC2.TATA-binding protein to DNA in the absence of TATA. 2005; J. Biol. Chem. 280:6222-6230

Blazek E, Mittler G, Meisterernst M. The mediator of RNA polymerase II. 2005; Chromosoma 113:399-408 Review.

Kleijman MP, Pereira LA, van Zeeburg HJT, Gilfillan S, Meisterernst M and Timmers HTM. NC2 alpha interacts with BTAF1and stimulates its ATP-dependent association with TBP. 2004; Mol. Cell. Biol. 22:10072-10082

Bourbon HM et al. A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. 2004; Mol. Cell. 14:553-557 Letter to the Editor.

Fukuda A, Nakadai T, Shimada M, Tsukui T, Matsumoto M, Nogi Y, Meisterernst M and Hisatake K. Transcriptional Coaktivator PC4 stimulates promoter escape and facilitates transcriptional synergy by GAL4-VP16. 2004; Mol. Cell. Biol. 14:6525-6535

Mittler G, Stuhler T, Santolin L, Uhlmann T, Kremmer E, Lottspeich F, Berti L, Meisterernst M. A novel docking site on Mediator is critical for activation by VP16 in mammalian cells. 2003; EMBO J. 22:6494-6504

Gilfillan S, Stelzer G, Kremmer E, Meisterernst M. Purification and transcription repression by negative cofactor 2. 2003; MethodsEnzymol. 370:467-479

Gwack Y, Baek HJ, Nakamura H, Lee SH, Meisterernst M, Roeder RG, Jung JU. Principal role of TRAP/mediator and SWI/SNF complexes in Kaposi's sarcoma-associated herpesvirus RTAmediated lytic reactivation. 2003; Mol. Cell. Biol. 23:2055-2056

De Luca A, Conti E, Grifone N, Amati F, Spalletta G, Caltagirone C, Bonaviri G, Pasini A, Gennarelli M, Stefano B, Berti L, Mittler G, Meisterernst M, Dallapiccola B, Novelli G. Association study between CAG trinucleotide repeats in the PCQAP gene (PC2 glutamine/Q-richassociated protein) and schizophrenia. 2003; Am. J. Med. Genet. 116:32-35