2023

E. Hoffmann, D. Schache, C. Höltke, J. Soltwisch, S. Niland, T. Krähling, K. Bergander, M. Grewer, C. Geyer, L. Groeneweg, J. A. Eble, T. Vogl, J. Roth, W. Heindel, B. Maus, A. Helfen, C. Faber, M. Wildgruber, M. Gerwing, V. Hoerr. Multiparametric chemical exchange saturation transfer MRI detects metabolic changes in breast cancer following immunotherapy. J Transl Med 21:577 (2023). DOI: 10.1186/s12967-023-04451-6

E. Hoffmann, M. Gerwing, T. Krähling, U. Hansen, K. Kronenberg, M. Masthoff, C. Geyer, C. Höltke, L. Wachsmuth, R. Schinner, V. Hoerr, W. Heindel, U. Karst, M. Eisenblätter, B. Maus, A. Helfen, C. Faber, M. Wildgruber. Vascular response patterns to targeted therapies in murine breast cancer models with divergent degrees of malignancy. Breast Cancer Res 25, 56 (2023). DOI: 10.1186/s13058-023-01658-9

E. Hoffmann, M. Gerwing, S. Niland, R. Niehoff, M. Masthoff, C. Keyer, L. Wachsmuth, E. Wilken, C. Höltke, W. Heindel, V. Hoerr, R. Schinner, P. Berger, T. Vogl, J. E. Eble, B. Maus, A. Helfen, M. Wildgruber, C. Faber. Profiling specific cell populations within the inflammatory tumor microenvironment by oscillating-gradient diffusion-weighted MRI. J. Immunother Cancer 11(3):e006092 (2023). DOI: 10.1136/jitc-2022-006092

W.-T. Zhao, K.-H. Herrmann, R. Sibgatulin, A. Nahardani, M. Krämer, B. Heitplatz V. van Marck, S. Reuter, J. R. Reichenbach, V. Hoerr. Perfusion and T2 Relaxation Time as Predictors of Severity and Outcome in Sepsis-Associated Acute Kidney Injury: A Preclinical MRI Study. J Magn Reson Imaging (2023). DOI: 10.1002/jmri.28698

M. Rohrbeck, V. Hoerr, I. Piccini, B. Greber, J. S. Schulte, S.-S. Hübner, E. Jeworutzki, C. Theiss, V. Matschke, J. Stypmann, A. Unger, H. Tran Ho, P. Disse, N. Strutz-Seebohm, C. Faber, F. U. Müller, S. Ludwig, U. Rescher, W. A. Linke, K. Klingel, K. Busch, S. Peischard, G. Seebohm. Pathophysiological Mechanisms of Cardiac Dysfunction in Transgenic Mice with Viral Myocarditis. Cells 12(4), 550 (2023). DOI: 10.3390/cells12040550

2022

M. Gerwing, E. Hoffmann, K. Kronenberg, U. Hansen, M. Masthoff, A. Helfen, C. Geyer, L. Wachsmuth, C. Höltke, B. Maus, V. HoerrT. Krähling, L. Hiddeßen, W. Heindel, U. Karst, M.A. Kimm, R. Schinner, M. Eisenblätter, C. Faber, M. Wildgruber. Multiparametric MRI enables for differentiation of different degrees of malignancy in two murine models of breast cancer. Frontiers in Oncology 12:1000036 (2022). DOI: 10.3389/fonc.2022.1000036

A. Nahardani, M. Krämer, M. Ebrahimi, K.-H. Herrmann, S. Leistikow, L. Linsen, S. Moradi, J. R. Reichenbach, V. Hoerr. Time-resolved velocity mapping at high magnetic fields: A preclinical comparison between stack-of-stars and cartesian 4D-Flow. Front. Phys. 10:963807 (2022). DOI: 103389/fphy.2022.963807

D. Schache, S. Bardin, L. Liobanu, C. Faber, V. Hoerr. Ultrafast CEST line scanning as a method to quantify mutarotation kinetics. J Magn Reson 342:107270 (2022). DOI: 10.1016/j.jmr.2022.107270

C. Ottow, S. Schmidt, R. Schulz, L. Sottmann, W. Heindel, T. Krähling, H. Pfeiffer, V. Vieth, A. Schmeling. Forensische Altersdiagnostik mittels Niederfeld-Magnetresonanztomographie. Rechtsmedizin (2022, Online first). DOI: 10.1007/s00194-022-00588-8

C. Schwarz, R. Buchholz, M. Jawad, V. Hoesker, C. Terwesten-Solé, U. Karst, L. Linsen, T. Vogl, V. Hoerr, M. Wildgruber, C. Faber. Fingerprints of Element Concentrations in Infective Endocarditis Obtained by Mass Spectrometric Imaging and t-Distributed Stochastic Neighbor Embedding. ACS Infect. Dis. 2022, 8, 2, 360–372. DOI: 10.1021/acsinfecdis.1c00485

2021

A. Nahardani, S. Leistikow, K. Grün, M. Krämer, K.-H. Herrmann, A. Schrepper, C. Jung, S. Moradi, P. C. Schulze, L. Linsen, J. R. Reichenbach, V. Hoerr, M. Franz. Pulmonary Arteriovenous Pressure Gradient and Time-Averaged Mean Velocity of Small Pulmonary Arteries Can Serve as Sensitive Biomarkers in the Diagnosis of Pulmonary Arterial Hypertension: A Preclinical Study by 4D-Flow MRI. Diagnostics. 12(1):58, 2021.

C. Schwarz, Y. Töre, V. Hoesker, S. Ameling, K. Grün, U. Völker, P. C. Schulze, M. Franz, C. Faber, F. Schaumburg, S. Niemann, V. Hoerr. Host-pathogen interactions of clinical S. aureus isolated to induce infective endocarditis. Virulence. 12(1):2073-2087, 2021.

M. Gerwing, T. Krähling, C. Schliemann, S. Harrach, C. Schwöppe, A.F. Berdel, S. Klein, W. Hartmann, E. Wardelmann, W.L. Heindel, G. Lenz, W.E. Berdel, M. Wildgruber. Multiparametric Magnetic Resonance Imaging for Immediate Target Hit Assessment of CD13-Targeted Tissue Factor tTF-NGR in Advanced Malignant Disease. Cancers. 13(23):5880, 2021.

2020

N. Schmitz, M. Timmen, K. Kostka, V. Hoerr, C. Schwarz, C. Faber, U. Hansen, R. Matthys, M.J. Raschke, R. Stange. A novel MRI compatible mouse fracture model to characterize and monitor bone regeneration and tissue composition. Sci Rep. 10(1):16238, 2020.

C. Schwarz, V. Hoerr, Y. Töre, V. Hösker, U. Hansen, H. Van de Vyver, S. Niemann, M.T. Kuhlmann, A. Jeibmann, M. Wildgruber, C. Faber. Isolating Crucial Steps in Induction of Infective Endocarditis With Preclinical Modeling of Host Pathogen Interaction. Front Microbiol. 11:1325, 2020.

C. Schliemann, M. Gerwing, H. Heinzow, S Harrach, C Schwöppe, M. Wildgruber, A.A. Hansmeier, L. Angenendt, A.F. Berdel, U. Stalmann, B. Berning, K. Kratz-Albers, K. Middelberg-Bisping, S. Wiebe, J. Albring, C. Wilms, W. Hartmann, E. Wardelmann, T. Krähling, W. Heindel, J. Gerss, E. Bormann, H. Schmidt, G. Lenz, T. Kessler, R.M. Mesters, W.E. Berdel. First-In-Class CD13-Targeted Tissue Factor tTF-NGR in Patients with Recurrent or Refractory Malignant Tumors: Results of a Phase I Dose-Escalation Study. Cancers 12(6):1488, 2020.

2019

B. Blankenhaus, F. Braza, R. Martins, P. Bastos-Amador, I. González-García, A.R. Carlos, I. Mahu, P. Faisca, J.M. Nunes, P. Ventura, V. Hoerr, S. Weis, J. Guerra, S. Cardoso, A. Domingos, M. López, M.P. Soares. Ferritin regulates organismal energy balance and thermogenesis. Mol Metab. 24:64-79, 2019.

L. Tuchscherr, C. Pöllath, A. Siegmund, S. Deinhardt-Emmer, V. Hoerr, C.M. Svensson, T.M. Figge, S. Monecke, B. Löffler. Clinical S. aureus isolates vary in their virulence to promote adaptation to the host. Toxins. 11(3), 2019

R. Köhnke, D. Kentrup, K. Schütte-Nütgen, M. Schäfers, U. Schnöckel, V. Hoerr, S. Reuter. Update on imaging-based diagnosis of acute renal allograft rejection. Am J Nucl Med Mol Imaging. 9(2):110-126, 2019.

U. Jehn, K. Schuette-Nuetgen, D. Kentrup, V. Hoerr, S. Reuter. Renal Allograft Rejection: Noninvasive Ultrasound- and MRI-Based Diagnostics. Contrast Media Mol Imaging. 2019:3568067, 2019.

2018

I. Gallitz, N. Lofruthe, L. Traeger, N. Bäumer, V. Hoerr, C. Faber, T. Kuhlmann, C. Müller-Tidow, A.U. Steinbicker. Deficiency of the BMP Type I receptor ALK3 partly protects mice from anemia of inflammation. BMC Physiol. 18(1):3, 2018.

V. Hoerr, M. Franz, M.W. Pletz, M. Diab, S. Niemann, C. Faber, T. Doenst, P.C. Schulze, S. Deinhardt-Emmer, B. Löffler. S. aureus endocarditis: Clinical aspects and experimental approaches. Int J Med Microbiol. 308(6):640-652, 2018.

2017

D. Kentrup, P. Bovenkamp, A. Busch, K. Schuette-Nuetgen, H. Pawelski, H. Pavenstädt, E. Schlatter, K.H. Herrmann, J.R. Reichenbach, B. Löffler, B. Heitplatz, V. Van Marck, N.N. Yadav, G. Liu, P.C.M. van Zijl, S. Reuter, V. Hoerr. GlucoCEST magnetic resonance imaging in vivo may be diagnostic of acute renal allograft rejection. Kidney Int. 92:757-764, 2017.

D. Abdurrachim, M. Nabben, V. Hoerr, M.T. Kuhlmann, P. Bovenkamp, J. Ciapaite, I.M.E. Geraets, W. Coumans, J.J.F.P. Luiken, J.F.C. Glatz, M. Schäfers, K. Nicolay, C. Faber, S. Hermann, J.J. Prompers. Diabetic db/db mice do not develop heart failure upon pressure overload: a longitudinal in vivo PET, MRI, and MRS study on cardiac metabolic, structural, and functional adaptations. Cardiovasc Res. 113:1148-1160, 2017.

M. Krämer, A.G. Motaal, K.H. Herrmann, B. Löffler, J.R. Reichenbach, G.J. Strijkers, V. Hoerr. Cardiac 4D phase-contrast CMR at 9.4 T using self-gated ultra-short echo time (UTE) imaging. J Cardiovasc Magn Reson. 19:39-52, 2017.

H. Van de Vyver, P.R. Bovenkamp, V. Hoerr, K. Schwegmann, L. Tuchscherr, S. Niemann, L. Kursawe, C. Grosse, A. Moter, U. Hansen, U. Neugebauer, M.T. Kuhlmann, G. Peters, S. Hermann, B. Löffler. A Novel Mouse Model of Staphylococcus aureus Vascular Graft Infection: Noninvasive Imaging of Biofilm Development in Vivo. Am J Pathol. 187:268-279, 2017.

S. Deinhardt-Emmer, V. Hoerr, B. Löffler. Vascular graft infection: a new model for treatment management? Future Microbiol. 12:651-654, 2017.

2016

V. Hoerr; G.E. Duggan; L. Zbytnuik; K.H. Poon; C. Große; U. Neugebauer; K. Methling; B. Löffler; H.J. Vogel. Characterization and prediction of the mechanism of action of antibiotics through NMR metabolomics. BMC Microbiol. 16:82-96, 2016.

D. Tang, S. Tao, Z. Chen., L. Koliesnik, P.G. Calmes, V. Hoerr, B. Han, N. Gebert, M. Zörnig, B. Löffler, Y. Morita, K.L. Rudolph. Dietary restriction improves repopulation but impairs lymphoid differentiation capacity of hematopoietic stem cells in early aging. J Exp Med. 213:535-553, 2016.

L. Tuchscherr*, C.A. Kreis*, V. Hoerr*, L. Flint, M. Hachmeister, J. Geraci, S. Bremer-Streck, M. Kiehntopf, E. Medina, M. Kribus, M. Raschke, M. Pletz, G. Peters, B. Löffler. Staphylococcus aureus develops increased resistance to antibiotics by forming dynamic small colony variants during chronic osteomyelitis. J Antimicrob Chemother. 71:438-448, 2016. *equally contributed.

2015

V. Hoerr, C. Faber, K. Schäfers. Correction of MRI-induced Geometrics Distortions in Whole-Body Small Animal PET-MRI. Med Phys. 42:3848-3858, 2015.

V. Hoerr, L.J. Florack, K. Nicolay, G.J. Strijkers. Imaging myocardial infarction using accelerated self-gated UTE cine MRI. Int J Cardiovasc Imaging. 31:83-94, 2015.

P.R. Bovenkamp, T. Brix, F. Lindemann, R. Holtmeier, D. Abdurrachim, M.T. Kuhlmann, G.J. Strijkers, J. Stypmann, K.H. Hinrichs, V. Hoerr. Velocity mapping of the aortic flow at 9.4 T in healthy mice and mice with induced heart failure using time-resolved three-dimensional phase contrast MRI (4D PC MRI). Magn Reson Mater Phy Biol Med. 28:315-327, 2015.