12:00–15:30 Lunch Buffet
Registration & Welcome Coffee
Session 1: Testis Formation I
15:30–16:00 Development of primordial germ cells (PGVs) - lessons from the
zebrafish.
Erez Raz, ZMBE, University Münster, Germany
16:00–16:30 Derivation of primate PGCs from pluripotent stem cells
Ufuk Günesdogan, University of Göttingen, Germany
16:30–17:00 From stem cells to spermatogonia: accomplishing a key step towards in vitro gametogenesis
Kotaro Sasaki, University of Pennsylvania, USA
17:00–17:15 Clonal dynamics in the germline
Tatsuro Ikeda, National Institute for Basic Biology, Japan; German Cancer Research Center, Germany
17:15–17:30 The function of spermatogonial stem cells: lessons from proteomic and phosphoprometic analysis
David Skerrett-Byrne, The University of Melbourne, Australia; Helmholtz Zentrum München, Germany
17:30–19:00 Dinner
19:00–20:00 Keynote Lecture
Presented by the European Academy of Andrology (EAA) and the International Society of Andrology (IAA)
Life choices and fertility
R. John Aitken, University of Newcastle, Australia
Session 2: Testis Formation II
09:00–09:30 Sex Determination in the mouse: in vivo and in vitro model systems
Nitzan Gonen, Bar-Ilan University, Israel
09:30–10:00 Germline differentiation directed by DNA methylation Deborah Bourc'his, PSL Research University, Paris, France
10:00–10:30 Chromatin and transcriptional dynamics during spermatogenesis
Julie Cocquet, Institut Cochin, Paris, France
10:30–10:45 The ageing germline - a tale of sperm DNA methylation
Sandra Laurentino, University of Münster, Germany
10:45–11:00 Revisiting testis steroidogenesis from fetal life to adulthood in the rat
Caroline Despicht, Technical University of Denmark, Lyngby, Denmark
11:00–11:30 Coffee Break
Session 3: Testis Function I
11:30–12:00 Keeping the Germline Clean: piRNAs Transposons and Epigenetic Defense
in the Testis
Dónal O'Carrol, Edinburgh, Scotland
12:00–12:15 Downregulation of transposable elements in the primate postnatal germline
Manuel Paturlanne, University of Münster, Germany
12:15–12:45 Building Bridges for Transposon Repression
Devanshi Jain, Rutgers University, NJ, USA
12:45–13:00 G-quadruplex targeting by CX-5461 as a novel therapeutic strategy in testicular germ cell tumors
Rashidul Islam, University of Bonn, Germany
13:00–14:30 Lunch
14:30–16:00 Miniposter Session 1
16:00–16:30 Coffee Break
Session 4: Testis Function II
16:30–17:00 Origin of the spermatogenic cycle and wave
Shosei Yoshida, NIBB, Japan
17:00–17:30 Hidden in Plain Sight: The Central Importance of Sertoli and Leydig Cells
in the Human Testis
Nathalie Dejucq-Rainsford, University Rennes, Frances
17:30–18:00 Structure determines function: the cellular framework enabling
bifunctionality in the mammalian testis
Marc Spehr, University Aachen, Germany
18:00–18:15 The dual role of CX43 in human testicular peritubular cells
Lina Scholz, LMU Munich, Germany
18:15–18:30 Molecular pathways under positive selection in the ageing human male germline
Han Leng Ng, University of Oxford, England
18:30–20:30 Dinner
Session 5: Sperm Production
09:00–09:30 Impact of germline mutations in the human
Raheleh Rahbari, Sanger Institute, England
09:30–10:00 Male fertility restoration: Mission possible!
Ellen Goossens, VUB, Brussels, Belgium
10:00–10:30 Sodium thiosulfate co-exposure protects immature human testicular germ cells from cisplatin-induced gonadotoxicity in vitro
Emma Kearney, University of Edinburgh, Scotland
10:30–10:45 Life without cytoplasm: how sperm sustain protein production
Wei Yan, Washington State University, USA
10:45–11:00 Galectin - 3 is a regulator of immunological homeostasis along the testicular-epididymal axis under healthy and chronic inflammatory conditions
Monika Fijak, University of Gießen, Germany
11:00–11:30 Coffee Break
11:30–13:00 Miniposter Session 2
13:00–14:30 Lunch
Session 6: Contraception
14:30–15:00 Non-hormonal approaches to disable sperm
Oliver Martin Fischer, Bayer AG, Berlin, Germany
15:00–15:30 Safety and efficacy of YCT-529, a non-hormonal male contraceptive Nadja Mannowetz, YourChoice Therapeutics, San Francisco, USA
15:30–15:45 Contraceptive discovery by phenotypic screening of human sperm
Alexandra Amaral, Nuvisan ICB GmbH, Berlin, Germany
15:45–16:00 PREVENT: Drug discovery pipeline for the developement of non-hormonal contraceptive strategies
Gina Merges, University of Bonn, Germany
16:00–20:00 Free Afternoon & Excursions
20:00–22:30 Gala Dinner
09:00–10:30 Miniposter Session 3
10:30–11:00 Coffee Break
Session 7: Sperm production and function
11:00–11:15 Probing and understanding the micromechanical and molecular enviroment of human testes
Isabell Andersson, University of Limerick, Ireland
11:15–11:45 Structural biology of transmembrane signaling in sperm - all eyes on
CatSper.
Christos Gatsogiannis, Münster, Germany
11:45–12:00 Molecular mechanisms controlling sperm-manchette formation and stabilization
Tzviya Zeev-Ben-Mordehai, Utrecht University, Netherlands
12:00–12:30 How sperm unlock the egg
Andrea Pauli, Vienna, Austria
12:30–13:00 Closing Remarks
13:00–14:00 Lunch
End of Conference