2023

Domínguez-Andrés J, Reinecke H, Sohrabi Y. The immune hunger games: the effects of fasting on monocytes. Cell Mol Immunol. 2023 May 10.

Ohnewein B, Shomanova Z, Paar V, Topf A, Jirak P, Fiedler L, Granitz C, Van Almsick V, Semo D, Zagidullin N, Dieplinger AM, Sindermann J, Reinecke H, Hoppe UC, Pistulli R, Motloch LJ. Effects of Angiotensin Receptor-Neprilysin Inhibitors (ARNIs) on the Glucose and Fat Metabolism Biomarkers Leptin and Fructosamine. J Clin Med. 2023 Apr 24;12(9):3083. 

Semo D, Obergassel J, Dorenkamp M, Hemling P, Strutz J, Hiden U, Müller N, Müller UA, Zulfikar SA, Godfrey R, Waltenberger J. The Sodium-Glucose Co-Transporter 2 (SGLT2) Inhibitor Empagliflozin Reverses Hyperglycemia-Induced Monocyte and Endothelial Dysfunction Primarily through Glucose Transport-Independent but Redox-Dependent Mechanisms. J Clin Med. 2023 Feb 8;12(4):1356. 

Dorenkamp M, Nasiry M, Semo D, Koch S, Löffler I, Wolf G, Reinecke H, Godfrey R. Pharmacological Targeting of the RAGE-NFκB Signalling Axis Impedes Monocyte Activation under Diabetic Conditions through the Repression of SHP-2 Tyrosine Phosphatase Function. Cells. 2023 Feb 3;12(3):513.

Kaur B, Sohrabi Y, Achreja A, Lisanti MP, Martinez-Outschoorn UE. Editorial: Hallmark of cancer: Reprogramming of cellular metabolism. Front Oncol. 2023 Jan 11;12:1126913. 

2022

Sohrabi Y, Reinecke H, Soehnlein O. Trilateral interaction between innervation, leukocyte, and adventitia: a new driver of atherosclerotic plaque formation. Signal Transduct Target Ther. 2022 Jul 23;7(1):249.

Findeisen HM, Voges VC, Braun LC, Sonnenberg J, Schwarz D, Körner H, Reinecke H, Sohrabi Y. LXRα Regulates oxLDL-Induced Trained Immunity in Macrophages. Int J Mol Sci. 2022 May 31;23(11):6166.

Schwarz D, Lipoldová M, Reinecke H, Sohrabi Y. Targeting inflammation with collagen. Clin Transl Med. 2022 May;12(5):e831.

Jirak P, van Almsick V, Dimitroulis D, Mirna M, Seelmaier C, Shomanova Z, Wernly B, Semo D, Dankl D, Mahringer M, Lichtenauer M, Hoppe UC, Reinecke H, Pistulli R, Larbig R, Motloch LJ. Dexamethasone Improves Cardiovascular Outcomes in Critically Ill COVID-19, a Real World Scenario Multicenter Analysis. Front Med (Lausanne). 2022 Feb 2;9:808221. 

Krayem I, Sohrabi Y, Javorková E, Volkova V, Strnad H, Havelková H, Vojtíšková J, Aidarova A, Holáň V, Demant P, Lipoldová M. Genetic Influence on Frequencies of Myeloid-Derived Cell Subpopulations in Mouse. Front Immunol. 2022 Jan 26;12:760881.

Lipoldová M, Sohrabi Y. Role of interferon-induced GTPases in leishmaniasis. PLoS Negl Trop Dis. 2022 Jan 27;16(1):e0010093.

Krayem I, Sohrabi Y, Javorková E, Volkova V, Strnad H, Havelková H, Vojtíšková J, Aidarova A, Holáň V, Demant P, Lipoldová M. Genetic Influence on Frequencies of Myeloid-Derived Cell Subpopulations in Mouse. Front Immunol. 2022 Jan 26;12:760881.

Sohrabi Y, Schwarz D, Reinecke H. LDL-C augments whereas HDL-C prevents inflammatory innate immune memory. Trends Mol Med. 2022 Jan;28(1):1-4.

2021

Makowski LM,Leffers M, Waltenberger J, Pardali E. Transforming growth factor-β1 signalling triggers vascular endothelial growth factor resistance and monocyte dysfunction in type 2 diabetes mellitus. J Cell Mol Med. 2021 Jun;25(11):5316-5325.

Sohrabi Y, Reinecke H. RIPK1 targeting protects against obesity and atherosclerosis. Trends Endocrinol Metab. 2021 Jul;32(7):420-422. 

Sohrabi Y, Reinecke H, Joosten LAB, Netea MG. Deadly COVID-19 among the elderly: Innate immune memory helping those most in need. Med (N Y). 2021 Apr 9;2(4):378-383.

Sohrabi Y, Reinecke H, Godfrey R. Altered Cholesterol and Lipid Synthesis Mediates Hyperinflammation in COVID-19. Trends Endocrinol Metab. 2021 Mar;32(3):132-134.

2020

Sohrabi Y, Dos Santos JC, Dorenkamp M, Findeisen H, Godfrey R, Netea MG, Joosten LA. Trained immunity as a novel approach against COVID-19 with a focus on Bacillus Calmette-Guérin vaccine: mechanisms, challenges and perspectives. Clin Transl Immunology. 2020 Dec 22;9(12):e1228.

Sohrabi Y, Lagache SMM, Voges VC, Semo D,  Sonntag GVH,  Hanemann I,  Kahles F,  Waltenberger J,  Findeisen HM, OxLDL-mediated immunologic memory in endothelial cells, JMCC, Available online 26 July 2020,

Sohrabi Y, Sonntag GVH, Braun LC, Lagache SMM, Liebmann M, Klotz L, Godfrey R, Kahles F, Waltenberger J, Findeisen HM. LXR Activation Induces a Proinflammatory Trained Innate Immunity-Phenotype in Human Monocytes. Front Immunol. 2020 Mar 10;11:353.

Hemling P, Zibrova D, Strutz J, Sohrabi Y, Desoye G, Schulten H, Findeisen H, Heller R, Godfrey R, Waltenberger J. Hyperglycemia-induced endothelial dysfunction is alleviated by thioredoxin mimetic peptides through the restoration of VEGFR-2-induced responses and improved cell survival. Int J Cardiol. 2020 Jun 1;308:73-81.

2019

Sohrabi Y, Lagache SMM, Schnack L, Godfrey R, Kahles F, Bruemmer D, Waltenberger J, Findeisen HM. mTOR-Dependent Oxidative Stress Regulates oxLDL-Induced Trained Innate Immunity in Human Monocytes. Front Immunol. 2019 Jan 22;9:3155.

Schnack L, Sohrabi Y, Lagache SMM, Kahles F, Bruemmer D, Waltenberger J, Findeisen HM. Mechanisms of Trained Innate Immunity in oxLDL Primed Human Coronary Smooth Muscle Cells. Front Immunol. 2019 Jan 23;10:13.

2018

Dorenkamp M, Müller JP, Shanmuganathan KS, Schulten H, Müller N, Löffler I, Müller UA, Wolf G, Böhmer FD, Godfrey R, Waltenberger J. Hyperglycaemia-induced methylglyoxal accumulation potentiates VEGF resistance of diabetic monocytes through the aberrant activation of tyrosine phosphatase SHP-2/SRC kinase signalling axis.  Sci Rep. 2018 Oct 2;8(1):14684.

Sohrabi Y, Godfrey R, Findeisen HM. Altered Cellular Metabolism Drives Trained Immunity. Trends Endocrinol Metab. 2018 Sep;29(9):602-605.

Tjaden K, Adam C, Godfrey R, Hanley PJ, Pardali E, Waltenberger J. Low density lipoprotein interferes with intracellular signaling of monocytes resulting in impaired chemotaxis and enhanced chemokinesis. Int J Cardiol. 2018 Mar 15;255:160-165.

Sohrabi Y, Lipoldová M. Mannose Receptor and the Mystery of Nonhealing Leishmania major Infection. Trends Parasitol. 2018 May;34(5):354-356.

Amodio G, Cichy J, Conde P, Matteoli G, Moreau A, Ochando J, Oral BH, Pekarova M, Ryan EJ, Roth J, Sohrabi Y, Cuturi MC, Gregori S. Role of myeloid regulatory cells (MRCs) in maintaining tissue homeostasis and promoting tolerance in autoimmunity, inflammatory disease and transplantation. Cancer Immunol Immunother. 2018 Oct 24. doi: 10.1007/s00262-018-2264-3.

Dorhoi A, Glaría E, Garcia-Tellez T, Nieuwenhuizen NE, Zelinskyy G, Favier B, Singh A, Ehrchen J, Gujer C, Münz C, Saraiva M, Sohrabi Y, Sousa AE, Delputte P, Müller-Trutwin M, Valledor AF. MDSCs in infectious diseases: regulation, roles, and readjustment. Cancer Immunol Immunother. 2018 Dec 19. doi: 10.1007/s00262-018-2277-y.