• Publications 2020

    1. Backhaus P, Büther F, Wachsmuth L, Frohwein L, Buchholz R, Karst U, Schäfers K, Hermann S, Schäfers M, Faber C (2020) Toward precise arterial input functions derived from DCE-MRI through a novel extracorporeal circulation approach in mice. Magn Reson Med 84(3): 1404-1415. Abstract
    2. Barca C, Foray C, Hermann S, Döring C, Schäfers M, Jacobs AH, Zinnhardt B (2020) Characterization of the inflammatory post-ischemic tissue by full volumetric analysis of a multimodal imaging dataset. Neuroimage 222: 117217. Abstract
    3. Helfen A, Große Hokamp N, Geyer C, Heindel W, Bremer C, Vogl T, Höltke C, Masthoff M, Barczyk-Kahlert K, Roth J, Wildgruber M, Eisenblaetter M (2020) Target-specific imaging of cathepsin and s100a8/a9 reflects specific features of malignancy and enables estimation of tumor malignancy. Mol Imaging Biol 22(1): 66-72. Abstract
    4. Kimm MA, Haas H, Stölting M, Kuhlmann M, Geyer C, Glasl S, Schäfers M, Ntziachristos V, Wildgruber M, Höltke C (2020) Targeting endothelin receptors in a murine model of myocardial infarction using a small molecular fluorescent probe. Mol Pharm 7(1): 109-117. Abstract
    5. Schwarz C, Hoerr V, Töre Y, Hösker V, Hansen U, Van de Vyver H, Niemann S, Kuhlmann MT, Jeibmann A, Wildgruber M, Faber C (2020) Isolating crucial steps in induction of infective endocarditis with preclinical modeling of host pathogen interaction. Front Microbiol 11: 1325. Abstract
    6. Schwegmann K, Hohn M, Hermann S, Schäfers M, Riemann B, Haufe G, Wagner S, Breyholz HJ (2020) Optimizing the biodistribution of radiofluorinated barbiturate tracers for matrix metalloproteinase imaging by introduction of fluorescent dyes as pharmacokinetic modulators. Bioconjug Chem 31(4): 1117-1132. Abstract
  • Publications 2019

    1. Bachg AC, Horsthemke M, Skryabin BV, Klasen T, Nagelmann N, Faber C, Woodham E, Machesky LM, Bachg S, Stange R, Jeong HW, Adams RH, Bähler M, Hanley PJ (2019) Phenotypic analysis of Myo10 knockout (Myo10tm2/tm2) mice lacking full-length (motorized) but not brain-specific headless myosin X. Sci Rep 9(1): 597-597. [IF 4.011] Abstract
    2. Helfen A, Große Hokamp N, Geyer C, Heindel W, Bremer C, Vogl T, Höltke C, Masthoff M, Barczyk-Kahlert K, Roth J, Wildgruber M, Eisenblaetter M (2020) Target-specific imaging of cathepsin and S100A8/A9 reflects specific features of malignancy and enables estimation of tumor malignancy. Mol Imaging Biol 22(1):66-72. [IF 3.341] Abstract
    3. Hohoff C, Zhang M, Ambrée O, Kravchenko M, Buschert J, Kerkenberg N, Gorinski N, Abdel Galil D, Schettler C, Vom Werth KL, Wewer MF, Schneider I, Grotegerd D, Wachsmuth L, Faber C, Skryabin BV, Brosius J, Ponimaskin E, Zhang W (2019) Deficiency of the palmitoyl acyltransferase ZDHHC7 impacts brain and behavior of mice in a sex-specific manner. Brain Struct Funct 224(6):2213-2230. [IF 3.622] Abstract
    4. Just N, Faber C (2019) Probing activation-induced neurochemical changes using optogenetics combined with functional magnetic resonance spectroscopy (o-fMRS): a feasibility study in the rat primary somatosensory cortex. J Neurochem [IF 4.870] (EPub ahead of print) Abstract
    5. Just N, Segelcke D, Sandbrink M, Pogatzki-Zahn E, Faber C (2019) Development of a stimulator for the characterization of mechanical-evoked pain-related supra-spinal processing using BOLD-fMRI in rodents. IEEE Trans Biomed Eng [IF 4.491] (EPub ahead of print)  Abstract
    6. Kalinin DV, Agoglitta O, Van de Vyver H, Melesina J, Wagner S, Riemann B, Schäfers M, Sippl W, Löffler B, Holl R (2019) Proline-based hydroxamates targeting the zinc-dependent deacetylase LpxC: Synthesis, antibacterial properties, and docking studies. Bioorg Med Chem 27 (10): 1997-2018. [IF 2.802] Abstract
    7. Masthoff M, Buchholz R, Beuker A, Wachsmuth L, Kraupner A, Albers F, Freppon F, Helfen A, Gerwing M, Höltke C, Hansen U, Rehkämper J, Vielhaber T, Heindel W, Eisenblätter M, Karst U, Wildgruber M, Faber C (2019) Introducing specificity to iron oxide nanoparticle imaging by combining 57Fe-based MRI and mass spectrometry. Nano Lett 19 (11): 7908-7917. [IF 12.279] PAPER OF THE MONTH 12/2019  Abstract
    8. Roll W, Markwardt NA, Masthoff M, Helfen A, Claussen J, Eisenblätter M, Hasenbach A, Hermann S, Karlas A, Wildgruber M, Ntziachristos V, Schäfers M (2019) Multispectral optoacoustic tomography of benign and malignant thyroid disorders - a pilot study. J Nucl Med 60(10):1461-1466. [IF 7.354]  Abstract
    9. Zinnhardt B, Belloy M, Fricke IB, Orije J, Guglielmetti C, Hermann S, Wagner S, Schäfers M, Van der Linden A, Jacobs AH (2019) Molecular imaging of immune cell dynamics during de- and remyelination in the cuprizone model of multiple sclerosis by [18F]DPA-714 PET and MRI.  Theranostics 9 (6): 1523-1537. [IF 8.063]  Abstract
  • Publications 2018

    1. Axer A, Hermann S, Kehr G, Clases D, Karst U, Fischer-Riepe L, Roth J, Fobker M, Schafers M, Gilmour R, Faust A (2018) Harnessing the Maltodextrin Transport Mechanism for Targeted Bacterial Imaging: Structural Requirements for Improved in vivo Stability in Tracer Design. ChemMedChem 13: 241-250. [IF 3.009] Abstract
    2. Butsch V, Borgel F, Galla F, Schwegmann K, Hermann S, Schafers M, Riemann B, Wunsch B, Wagner S (2018) Design, (Radio)Synthesis, and in Vitro and in Vivo Evaluation of Highly Selective and Potent Matrix Metalloproteinase 12 (MMP-12) Inhibitors as Radiotracers for Positron Emission Tomography. J Med Chem 61: 4115-4134. [IF 6.253] Abstract
    3. Gran S, Honold L, Fehler O, Zenker S, Eligehausen S, Kuhlmann MT, Geven E, den Bosch M van, van Lent P, Spiekermann C, Hermann S, Vogl T, Schäfers M, Roth J (2018) Imaging, myeloid precursor immortalization, and genome editing for defining mechanisms of leukocyte recruitment_in vivo. Theranostics 8: 2407-2423. [IF 8.537] Abstract
    4. Heming M, Gran S, Jauch S-L, Fischer-Riepe L, Russo A, Klotz L, Hermann S, Schafers M, Roth J, Barczyk-Kahlert K (2018) Peroxisome Proliferator-Activated Receptor-gamma Modulates the Response of Macrophages to Lipopolysaccharide and Glucocorticoids. Front Immunol 9: 893. [IF 5.511]Abstract
    5. Hohn M, Chang M, Meisel JE, Frost E, Schwegmann K, Hermann S, Schäfers M, Riemann B, Haufe G, Breyholz HJ, Wagner S (2018) Synthesis and preliminary in vitro and in vivo evaluation of thiirane-based slow binding MMP inhibitors as potential radiotracers for PET imaging. Chemistry Select 3: 11729-11736. [IF 1.505] Abstract
    6. Hugenberg V, Behrends M, Wagner S, Hermann S, Schafers M, Kolb HC, Szardenings K, Walsh JC, Gomez LF, Kopka K, Haufe G (2018) Synthesis, radiosynthesis, in vitro and first in vivo evaluation of a new matrix metalloproteinase inhibitor based on gamma-fluorinated alpha-sulfonylaminohydroxamic acid. EJNMMI Radiopharm Chem 3: 10. [IF pending] Abstract
    7. Lohöfer F, Hoffmann L, Buchholz R, Huber K, Glinzer K, Kosanke K, Feuchtinger A, Aichler M, Feuerecker B, Kaissis G, Rummeny EJ, Höltke C, Faber C, Schilling F, Botnar RM, Walch AK, Karst U, Wildgruber M  (2018) Molecular imaging of myocardial infarction with Gadofluorine P – A combined magnetic resonance and mass spectrometry imaging Approach. Heliiyon 4(4): e00606. [IF pending] Abstract
    8. Masthoff M, Gran S, Zhang X, Wachsmuth L, Bietenbeck M, Helfen A, Heindel W, Sorokin S, Roth J, Eisenblätter M, Wildgruber M, Faber C (2018)Temporal window for detection of inflammatory disease using dynamic cell tracking with time-lapse MRI. Sci Rep 8: 9563. [IF 4.122] Abstract
    9. Masthoff M, Helfen A, Claussen J, Roll W, Karlas A, Becker H, Gabriels G, Riess J, Heindel W, Schafers M, Ntziachristos V, Eisenblatter M, Gerth U, Wildgruber M (2018) Multispectral optoacoustic tomography of systemic sclerosis. J Biophotonics  e201800155. [IF 3.768] Abstract
    10. Neumann PA, Twardy V, Becker F, Geyer C, Schwegmann K, Mohr A, Faust A, Lenz P, Rijcken E (2018) Assessment of MMP-2/-9 expression by fluorescence endoscopy for evaluation of anastomotic healing in a murine model of anastomotic leakage. PLoS One 13(3):e0194249. [IF 2.766]Abstract
    11. Schelhaas S, Heinzmann K, Honess DJ, Smith D-M, Keen H, Heskamp S, Witney TH, Besret L, Doblas S, Griffiths JR, Aboagye EO, Jacobs AH (2018) 3‘-Deoxy-3‘-[(18)F]Fluorothymidine Uptake Is Related to Thymidine Phosphorylase Expression in Various Experimental Tumor Models. Mol Imaging Biol 20: 194-199. [IF 3.626] Abstract
    12. Schelhaas S, Wachsmuth L, Hermann S, Rieder N, Heller A, Heinzmann K, Honess DJ, Smith D-M, Fricke IB, Just N, Doblas S, Sinkus R, Doring C, Schafers KP, Griffiths JR, Faber C, Schneider R, Aboagye EO, Jacobs AH (2018) Thymidine Metabolism as a Confounding Factor for 3‘-Deoxy-3‘-(18)F-Fluorothymidine Uptake After Therapy in a Colorectal Cancer Model. J Nucl Med 59: 1063-1069. [IF 7.439]Abstract
    13. Völler T, Faust A, Roth J, Schafers M, Vogl T, Hermann S (2018) A Non-Peptidic S100A9 Specific Ligand for Optical Imaging of Phagocyte Activity In Vivo. Mol Imaging Biol 20: 407-416. [IF 3.626] Abstract
    14. Vogl T, Stratis A, Wixler V, Voller T, Thurainayagam S, Jorch SK, Zenker S, Dreiling A, Chakraborty D, Frohling M, Paruzel P, Wehmeyer C, Hermann S, Papantonopoulou O, Geyer C, Loser K, Schafers M, Ludwig S, Stoll M, Leanderson T, Schultze JL, Konig S, Pap T, Roth J (2018) Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation. J Clin Invest 128: 1852-1866. [IF 13.251] Abstract
    15. Wiesmann M, Timmer NM, Zinnhardt B, Reinhard D, Eligehausen S, Konigs A, Ben Jeddi H, Dederen PJ, Jacobs AH, Kiliaan AJ (2018) Effect of a multinutrient intervention after ischemic stroke in female C57Bl/6 mice. J Neurochem 144: 549-564. [IF 4.609] Abstract
  • Publications 2017

    1. Abdurrachim D, Nabben M, Hoerr V, Kuhlmann MT, Bovenkamp P, Ciapaite J, Geraets IME, Coumans W, Luiken JJFP, Glatz JFC, Schafers M, Nicolay K, Faber C, Hermann S, Prompers JJ (2017) Diabetic db/db mice do not develop heart failure upon pressure overload: a longitudinal in vivo PET, MRI, and MRS study on cardiac metabolic, structural, and functional adaptations. Cardiovasc Res 113: 1148-1160. [IF 5.878] Abstract
    2. Axer A, Hermann S, Kehr G, Clases D, Karst U, Fischer-Riepe L, Roth J, Fobker M, Schafers M, Gilmour R, Faust A (2017) Harnessing the Maltodextrin Transport Mechanism for Targeted Bacterial Imaging: Structural Requirements for improved in vivo Stability in Tracer Design. ChemMedChem (Epub ahead of print) [IF 3.225] Abstract
    3. Fricke IB, Schelhaas S, Zinnhardt B, Viel T, Hermann S, Couillard-Despres S, Jacobs AH (2017) In vivo bioluminescence imaging of neurogenesis - the role of the blood brain barrier in an experimental model of Parkinson's disease. Eur J Neurosci 45: 975-986 [IF 2.941] Abstract
    4. Grabner A, Schramm K, Silswal N, Hendrix M, Yanucil C, Czaya B, Singh S, Wolf M, Hermann S, Stypmann J, Di Marco GS, Brand M, Wacker M, Faul C (2017) FGF23/FGFR4-mediated left ventricular hypertrophy is reversible. Sci Rep 7:1993 [IF 4.259] Abstract
    5. Hillen J, Geyer C, Heitzmann M, Beckmann D, Krause A, Winkler I, Pavenstädt H, Bremer C, Pap T, Korb-Pap A (2017) Structural cartilage damage attracts circulating rheumatoid arthritis synovial fibroblasts into affected joints. Arthritis Res Ther 19: 40. [IF 4.121] Abstract
    6. Mücke MM, Bettenworth D, Geyer C, Schwegmann K, Poremba C, Schäfers M, Domagk D, Höltke C, Lenz P (2017) Targeting mucosal Endothelin-A-receptor expression by fluorescence endoscopy is feasible to detect and characterize colitis-associated cancer in mice. Inflamm Bowel Dis 24: 111-122. [IF 4.525] Abstract
    7. Schelhaas S, Heinzmann K, Honess DJ, Smith DM, Keen H, Heskamp S, Witney TH, Besret L, Doblas S, Griffiths JR, Aboagye EO, Jacobs AH (2017) 3'-Deoxy-3'-[18F]Fluorothymidine Uptake Is Related to Thymidine Phosphorylase Expression in Various Experimental Tumor Models.
      Mol Imaging Biol (Epub ahead of print) [IF 3.466] Abstract
    8. Schwalm M*, Schmid F*, Wachsmuth L*, Backhaus H, Kronfeld A, Aedo-Jury F, Prouvot PH, Fois C, Albers F, van Alst T, Faber C*, Stroh A* (2017). Cortex-wide BOLD fMRI activity reflects locally-recorded slow oscillation-associated calcium waves. eLife 6:e27602. [IF 7.725] Abstract
    9. Thunemann M, Schörg BF, Feil S, Lin Y, Voelkl J, Golla M, Vachaviolos A, Kohlhofer U, Quintanilla-Martinez L, Olbrich M, Ehrlichmann W, Reischl G, Griessinger CM, Langer HF, Gawaz M, Lang F, Schäfers M, Kneilling M, Pichler BJ, Feil R (2017) Cre/lox-assisted non-invasive in vivo tracking of specific cell populations by positron emission tomography. Nat Commun 8: 444. [IF 12.124] Abstract  
    10. Van de Vyver H, Bovenkamp PR, Hoerr V, Schwegmann K, Tuchscherr L, Niemann S, Kursawe L, Grosse C, Moter A, Hansen U, Neugebauer U, Kuhlmann MT, Peters G, Hermann S, Loffler B (2017) A Novel Mouse Model of Staphylococcus aureus Vascular Graft Infection: Noninvasive Imaging of Biofilm Development in Vivo. Am J Pathol 187: 268-279. [IF 4.057] Abstract
    11. Voeller T, Faust A, Roth J, Schafers M, Vogl T, Hermann S (2017) A Non-Peptidic S100A9 Specific Ligand for Optical Imaging of Phagocyte Activity In Vivo. Mol Imaging Biol  (Epub ahead of print) [IF 3.466] Abstract  
    12. Wiesmann M, Timmer NM, Zinnhardt B, Reinhard D, Eligehausen S, Königs A, Ben Jeddi H, Dederen PJ, Jacobs AH, Kiliaan AJ (2017) Effect of a multinutrient intervention after ischemic stroke in female C57Bl/6 mice. J Neurochem (Epub ahead of print) [IF 4.083] Abstract
    13. Wiesmann M, Zinnhardt B, Reinhardt D, Eligehausen S, Wachsmuth L, Hermann S, Dederen PJ, Hellwich M, Kuhlmann MT, Broersen LM, Heerschap A, Jacobs AH, Kiliaan AJ (2017) A specific dietary intervention to restore brain structure and function after ischemic stroke. Theranostics 7: 493-512. [IF 8.712] Abstract  
    14. Zinnhardt B, Pigeon H, Theze B, Viel T, Wachsmuth L, Fricke IB, Schelhaas S, Honold L, Schwegmann K, Wagner S, Faust A, Faber C, Kuhlmann MT, Hermann S, Schafers M, Winkeler A, Jacobs AH (2017) Combined PET Imaging of the Inflammatory Tumor Microenvironment Identifies Margins of Unique Radiotracer Uptake. Cancer Res 77: 1831-1841. [IF 9.122] Abstract
  • Publications 2016

    1. Amirmohseni S, Segelcke D, Reichl S, Wachsmuth L, Görlich D, Faber C, Pogatzki-Zahn E (2016) Characterization of incisional and inflammatory pain in rats using functional tools of MRI. Neuroimage 127: 110-122. [IF 5.835] Abstract
    2. Fricke IB, Viel T, Worlitzer MM, Collmann FM, Vrachimis A, Faust A, Wachsmuth L, Faber C, Dollé F, Kuhlmann MT, Schäfers K, Hermann S, Schwamborn JC, Jacobs AH (2016) 6-hydroxydopamine-induced Parkinson's disease-like degeneration generates acute microgliosis and astrogliosis in the nigrostriatal system but no bioluminescence imaging-detectable alteration in adult neurogenesis. Eur J Neurosci 43: 1352-1365. [IF 2.941] Abstract
    3. Gerwien H, Hermann S, Zhang X, Korpos E, Song J, Kopka K, Faust A, Wenning C, Gross CC, Honold L, Melzer N, Opdenakker G, Wiendl H, Schäfers M, Sorokin L (2016) Imaging matrix metalloproteinase activity in multiple sclerosis as a specific marker of leukocyte penetration of the blood-brain barrier. Sci Transl Med 8: 364ra152. [IF 16.796] Abstract
    4. Grabner A, Kentrup D, Pawelski H, Mühlmeister M, Biermann C, Heitplatz B, Van Marck V, Bettinger T, Pavenstädt H, Schlatter, Stypmann J, Tiemann K, Reuter S (2016) Renal contrast enhanced Sonography findings in a model of acute cellular allograft rejection. Am J Transplant 16: 1612-1619. [IF 6.165] Abstract
    5. Hermann S, Kuhlmann MT, Starsichova A, Eligehausen S, Schäfers K, Stypmann J, Tiemann K, Levkau B, Schäfers M (2016) Imaging Reveals the Connection Between Spontaneous Coronary Plaque Ruptures, Atherothrombosis, and Myocardial Infarctions in HypoE/SRBI-/- Mice. J Nucl Med 57: 1420-1427. [IF 6.646] Abstract
    6. Hugenberg V, Hermann S, Galla F, Schäfers M, Wünsch B, Kolb HC, Szardenings K, Lebedev A, Walsh JC, Mocharla VP, Gangadharmath UB, Kopka K, Wagner S (2016) Radiolabeled hydroxamate-based matrix metalloproteinase inhibitors: How chemical modifications affect pharmacokinetics and metabolic stability. Nucl Med Biol 43: 424-437. [IF 2.426] Abstract
    7. Keul P, van Borren MM, Ghanem A, Müller FU, Baartscheer A, Verkerk AO, Stümpel F, Schulte JS, Hamdani N, Linke WA, van Loenen P, Matus M, Schmitz W, Stypmann J, Tiemann K, Ravesloot JH, Alewijnse AE, Hermann S, Spijkers LJ, Hiller KH, Herr D, Heusch G, Schäfers M, Peters SL, Chun J, Levkau B (2016) Sphingosine-1-Phosphate Receptor 1 Regulates Cardiac Function by Modulating Ca2+ Sensitivity and Na+/H+ Exchange and Mediates Protection by Ischemic Preconditioning. J Am Heart Assoc 5: pii: e003393.  [IF 4.863] Abstract
    8. Klasen T, Faber C (2016) Assessment of the myelin water fraction in rodent spinal cord using T2-prepared ultrashort echo time MRI. MAGMA 29: 875-884. [IF 2.638] Abstract
    9. O'Halloran PJ, Viel T, Murray DW, Wachsmuth L, Schwegmann K, Wagner S, Kopka K, Jarzabek MA, Dicker P, Hermann S, Faber C, Klasen T, Schäfers M, O'Brien D, Prehn JH, Jacobs AH, Byrne AT (2016) Mechanistic interrogation of combination bevacizumab/dual PI3K/mTOR inhibitor response in glioblastoma implementing novel MR and PET imaging biomarkers. Eur J Nucl Med Mol Imaging 43: 1673-1683. [IF 7.277] Abstract
    10. Schelhaas S, Held A, Bäumer N, Viel T, Hermann S, Müller-Tidow C, Jacobs AH (2016) Preclinical Evidence That 3'-Deoxy-3'-[18F]Fluorothymidine PET Can Visualize Recovery of Hematopoiesis after Gemcitabine Chemotherapy. Cancer Res 76: 7089-7095. [IF 9.122] Abstract
    11. Schelhaas S, Held A, Wachsmuth L, Hermann S, Honess DJ, Heinzmann K, Smith DM, Griffiths JR, Faber C, Jacobs AH (2016) Gemcitabine Mechanism of Action Confounds Early Assessment of Treatment Response by 3'-Deoxy-3'-[18F]Fluorothymidine in Preclinical Models of Lung Cancer. Cancer Res 76: 7096-7105. [IF 9.122] Abstract
    12. Schmid F, Wachsmuth L, Schwalm M, Prouvot PH, Jubal ER, Fois C, Pramanik G, Zimmer C, Faber C, Stroh A (2016) Assessing sensory versus optogenetic network activation by combining (o)fMRI with optical Ca2+ recordings. J Cereb Blood Flow Metab 36: 1885-1900. [IF 5.081] Abstract
    13. Vahle AK, Hermann S, Schäfers M, Wildner M, Kerem A, Oztürk E, Jure-Kunkel M, Franklin C, Lang S, Brandau S (2016) Multimodal imaging analysis of an orthotopic head and neck cancer mouse model and application of anti-CD137 tumor immune therapy. Head Neck 38: 542-549. [IF 3.376] Abstract
  • Publications 2015

    1. Becker A, Große Hokamp N, Zenker S, Flores-Borja F, Barzcyk K, Varga G, Roth J, Geyer C, Heindel W, Bremer C, Vogl T, Eisenblätter M (2015) Optical in vivo imaging of the alarmin S100A9 in tumor lesions allows for estimation of the individual malignant potential by evaluation of tumor host-cell interaction. J Nucl Med 56: 450-456. [IF 5.849] Abstract
    2. Brand C, Dencks S, Schmitz G, Mühlmeister M, Stypmann J, Ross R, Hintelmann H, Schliemann C, Müller-Tidow C, Mesters RM, Berdel WE, Schwöppe C (2015) Low-Energy Ultrasound treatment improves regional tumor vessel infarction by retargeted tissue factor. J Ultrasound Med 34: 1227-1236. [IF 1.544] Abstract
    3. Doblas S, Almeida GA, Blé FX, Garteiser P, Hoff BA, McIntyre DJO, Wachsmuth L, Chenevert TL, Faber C, Griffiths JR, Jacobs AH, Morris DM, O´Connor JPB, Robinson SP, Van Beers BE, Waterton JC (2015) Apparent Diffusion Coefficient Is Highly Reproducible on Preclinical Imaging Systems: Evidence From a Seven-Center Multivendor Study. J Magn Reson Imaging 42: 1759-1764.
      [IF 3.250] Abstract
    4. Faust A, Völler T, Busch F, Schäfers M, Roth J, Hermann S, Vogl T (2015) Development and evaluation of a non-peptidic ligand for the molecular imaging of inflammatory processes using S100A9 (MRP14) as a novel target. Chem Commun (Camb) 51: 15637-15640. [IF 6.567] Abstract
    5. Frohwein LJ, Hoerr V, Faber C, Schäfers KP (2015) Correction of MRI-induced geometric distortions in whole-body small animal PET-MRI. Med Phys 42: 3848-3858. [IF 2.496] Abstract
    6. Reilmann R, Lippross V, Hölzner E, Gigengack F, Bohlen S, Kugel H, Deppe M, Osada N, Lücke M, Riess O, Nguyen HP, von Hörsten S, Schäfers K, Schäfers M, Jacobs AH, Hermann S (2015) FDG µPET fails to detect a disease-specific phenotype in rats transgenic for Huntington´s Disease – A 15 months follow-up study. J Huntingtons Dis 4: 37-47. [IF -] Abstract
    7. Santschi N, Wagner S, Daniliuc C, Hermann S, Schäfers M, Gilmour R (2015) Synthesis of 2-[18F]Fluoro-2-deoxyisosorbide 5-mononitrate and assessment of its in vivo biodistribution as determined by dynamic Positron Emission Tomography (PET). ChemMedChem 10: 1724-1732. [IF 2.980] Abstract
    8. Song J, Wu C, Korpos E, Zhang X, Agrawal SM, Wang Y, Faber C, Schäfers M, Körner H, Opdenakker G, Hallmann R, Sorokin L (2015) Focal MMP-2 and MMP-9 activity at the blood-brain barrier promotes chemokine-induced leukocyte migration. Cell Rep 10: 1040-1054. [IF 7.870] Abstract

  • Publications 2014

    1. Alsibai W, Hahnenkamp A, Eisenblätter M, Riemann B, Schäfers M, Bremer C, Haufe G, Höltke C (2014) Fluorescent Non-peptidic RGD Mimetics with High Selectivity for alphaVbeta3 vs alphaIIbbeta3 Integrin Receptor: Novel probes for in Vivo Optical Imaging. J Med Chem 57: 9971-9982. [IF 5.480] Abstract
    2. Biesemann N, Mendler L, Wietelmann A, Hermann S, Schäfers M, Krüger M, Boettger T, Borchardt T, Braun T (2014) Myostatin regulates energy homeostasis in the heart and prevents heart failure. Circ Res 115: 296-310. [IF 11.089]Abstract
    3. Hahnenkamp A, Alsibai W, Bremer C, Höltke C (2014) Optimizing the bioavailability of small molecular optical imaging probes by conjugation to an albumin affinity tag. J Controlled Release 186: 32-40. [IF 7.261] Abstract
    4. Hoerr V, Faber C (2014) Magnetic resonance imaging characterization of microbial infections. J Pharm Biomed Anal 93: 136-146. [IF 2.829] REVIEW Abstract
    5. Persigehl T, Ring J, Bremer C, Heindel W, Holtmeier R, Stypmann J, Claesener M, Hermann S, Schäfers M, Zerbst C, Schliemann C, Mesters RM, Berdel WE, Schwöppe C (2014) Non-invasive monitoring of tumor-vessel infarction by retargeted truncated tissue factor tTF–NGR using multi-modal imaging. Angiogenesis 17: 235-246. [IF 4.410] Abstract
    6. Schelhaas S, Wachsmuth L, Viel T, Honess DJ, Heinzmann K, Smith DM, Hermann S, Wagner S, Kuhlmann MT, Müller-Tidow C, Kopka K, Schober O, Schäfers M, Schneider R, Aboagye EO, Griffiths J, Faber C, Jacobs AH (2014) Variability of Proliferation and Diffusion in Different Lung Cancer Models as Measured by 3'-Deoxy-3'-18F-Fluorothymidine PET and Diffusion-Weighted MR Imaging. J Nucl Med 55: 983-988. [IF 5.563] Abstract
    7. Ring J, Hoerr V, Tuchscherr L, Kuhlmann MT, Löffler B, Faber C (2014) MRI visualization of Staphylococcus aureus-induced infective endocarditis in mice. PLoS One 9(9):e107179. [IF 3.534] Abstract
    8. Tucci S, Flögel U, Hermann S, Sturm M, Schäfers M, Spiekerkoetter U (2014) Development and pathomechanisms of cardiomyopathy in very long-chain acyl-CoA dehydrogenase deficient (VLCAD(-/-)) mice. Biochim Biophys Acta 1842: 677-685. [IF 5.089] Abstract
    9. Vahle AK, Domikowsky B, Schwöppe C, Krähling H, Mally S, Schäfers M, Hermann S, Shahin V, Haier J, Schwab A, Stock C (2014) Extracellular matrix composition and interstitial pH modulate NHE1-mediated melanoma cell motility. Int J Oncol 44: 78-90. [IF 3.025] Abstract
    10. van Duijnhoven SM, Robillard MS, Hermann S, Kuhlmann MT, Schäfers M, Nicolay K, Grüll H (2014) Imaging of MMP activity in postischemic cardiac remodeling using radiolabeled MMP-2/9 activatable peptide probes. Mol Pharm 11: 1415-1423. [IF 4.120] Abstract
    11. Vogl T, Eisenblätter M, Völler T, Zenker S, Hermann S, van Lent P, Faust A, Geyer C, Petersen B, Roebrock K, Schäfers M, Bremer C, Roth J (2014) Alarmin S100A8/S100A9 as a biomarker for molecular imaging of local inflammatory activity. Nat Commun 5: 4593. [IF 29.648] Abstract
    12. Wenning C, Kloth C, Kuhlmann MT, Jacobs AH, Schober O, Hermann S, Schäfers MA (2014) Serial F-18-FDG PET/CT distinguishes inflamed from stable plaque phenotypes in shear-stress induced murine atherosclerosis. Atherosclerosis 234: 276-282. [IF 3.971] Abstract

  • Publications 2013

    1. Balla DZ, Gottschalk S, Shajan G, Ueberberg S, Schneider S, Hardtke-Wolenski M, Jaeckel E, Hoerr V, Faber C, Scheffler K, Pohmann R and Engelmann J (2013) In vivo visualization of single native pancreatic islets in the mouse.  Contrast Media Mol Imaging 8: 495-504. [IF 3.333] Abstract
    2. Bettenworth D, Reuter S, Hermann S, Weckesser M, Kerstiens L, Stratis A, Nowacki TM, Ross M, Lenze F, Edemir B, Maaser C, Pap T, Koschmieder S, Heidemann J, Schäfers M, Lugering A (2013) Translational 18F-FDG PET/CT Imaging to Monitor Lesion Activity in Intestinal Inflammation. J Nucl Med 54: 748-755. [IF 5.563]Abstract
    3. Grabner A, Kentrup D, Edemir B, Sirin Y, Pavenstädt H, Schlatter E, Schober O, Schäfers M, Schnöckel U, Reuter S (2013) PET with 18F-FDG-labeled T lymphocytes for diagnosis of acute rat renal allograft rejection. J Nucl Med 54: 1147-1153. [IF 5.563] Abstract
    4. Grabner A, Kentrup D, Schnöckel U, Gabriels G, Schröter R, Pavenstädt H, Schober O, Schlatter E, Schäfers M, Reuter S (2013) Non-invasive imaging of acute allograft rejection after rat renal transplantation using 18F-FDG PET. J Vis Exp e4240. [IF pending] Abstract
    5. Hahnenkamp A, Schäfers M, Bremer C, Höltke C (2013) Design and Synthesis of Small-Molecule Fluorescent Photoprobes Targeted to Aminopeptdase N (APN/CD13) for Optical Imaging of Angiogenesis. Bioconjugate Chemistry 24: 1027-1038. [IF 4.821] Abstract
    6. Hoerr V, Nagelmann N, Nauerth A, Kuhlmann MT, Stypmann J, Faber C (2013) Cardiac-respiratory self-gated cine ultra-short echo time (UTE) cardiovascular magnetic resonance for assessment of functional cardiac parameters at high magnetic fields. J Cardiovasc Magn Reson 15: 59. [IF 5.1124] Abstract
    7. Hoerr V, Tuchscherr L, Hüve J, Nippe N, Loser K, Glyvuk N, Tsytsyura Y, Holtkamp M, Sunderkötter C, Karst U, Klingauf J, Peters G, Löffler B, Faber C (2013) Bacteria tracking by in vivo magnetic resonance imaging. BMC Biol 11:63. [IF 7.431] Abstract
    8. Hugenberg V, Riemann B, Hermann S, Schober O, Schäfers M, Szardenings K, Lebedev A, Gangadharmath U, Kolb H, Walsh J, Zhang W, Kopka K, Wagner S (2013) Inverse 1,2,3-Triazole-1-yl-ethyl Substituted Hydroxamates as Highly Potent Matrix Metalloproteinase Inhibitors: (Radio)synthesis, in Vitro and First in Vivo Evaluation. J Med Chem 56: 6858-6870. [IF 5.480] Abstract
    9. Larmanm J, Frenzel T, Schmitz M, Hahnenkamp A, Demmer P, Immenschuh S, Tietge UJF, Bremer C, Theilmeier G (2013) In vivo Fluorescence-mediated Tomography Imaging Demonstrates Atorvastatin-mediated Reduction of Lesion Macrophages in ApoE-/- Mice. Anesthesiology 119: 129-141. [IF 6.168] Abstract
    10. Limpachayaporn P, Wagner S, Kopka K, Hermann S, Schäfers M, Haufe G (2013) Synthesis, 18F-radiolabeling, and in vivo biodistribution studies of N-fluorohydroxybutyl isatin sulfonamides using positron emission tomography. J Med Chem 56: 4509-4520. [IF 5.480] Abstract
    11. Neesse A, Hahnenkamp A, Griesmann H, Buchholz M, Hahn SA, Maghnouj A, Fendrich V, Ring J, Sipos B, Tuveson DA, Bremer C, Gress TM, Michl P (2013) Claudin-4-targeted optical imaging detects pancreatic cancer and its precursor lesions. Gut 62: 1034-1043. [IF 13.319] Abstract
    12. Persigehl T, Ring J, Bremer C, Heindel W, Holtmeier R, Stypmann J, Claesener M, Hermann S, Schäfers M, Zerbst C, Schliemann C, Mesters RM, Berdel WE, Schwöppe C (2014) Non-invasive monitoring of tumor-vessel infarction by retargeted truncated tissue factor tTF-NGR using multi-modal imaging. Angiogenesis 17: 235-246.  [IF 4.410] Abstract
    13. Steingräber AK, Schelhaas S, Faust A, Jacobs AH, Schäfers M, Goerge T (2013) Molecular imaging reveals time course of MMP activity in acute cutaneous vasculitis in vivo. Exp Dermatol 22: 730-735. [IF 4.115] Abstract
    14. Waschkau B, Faust A, Schäfers M, Bremer C (2013) Performance of a new fluorescence-labeled MMP inhibitor to image tumor MMP activity in vivo in comparison to an MMP-activatable probe. Contrast Media Mol Imaging 8: 1-11. [IF 3.333] Abstract

  • Publications 2012

    1. Bertrand J, Nitschke Y, Fuerst M, Hermann S, Schäfers M, Sherwood J, Nalesso G, Ruether W, Rutsch F, Dell‘Accio F, Pap T (2012) Decreased levels of nucleotide pyrophosphatase phosphodiesterase 1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice. Ann Rheum Dis 71: 1249-1253. [IF 9.111] Abstract
    2. Büther K, Compeer MG, De Mey JG, Schober O, Schäfers M, Bremer C, Riemann B, Höltke C (2012) Assessment of endothelin-A receptor expression in subcutaneous and orthotopic thyroid carcinoma xenografts in vivo employing optical imaging methods. Endocrinology 153: 2907-2918. [IF 4.717] Abstract
    3. Claesener M, Breyholz HJ, Hermann S, Faust A, Wagner S, Schober O, Schäfers M, Kopka K (2012) Efficient synthesis of a fluorine-18 labeled biotin derivative. Nucl Med Biol 39: 1189-1194. [IF 2.517] Abstract
    4. Hischemöller A, Walter C, Weiler V, Hummel H, Thepen T, Huhn M, Barth S, Hoheisel W, Köhler K, Dimova-Landen D, Bremer C, Haase M and Waldeck J (2012) Labeling of Anti-MUC-1 Binding Single Chain Fv Fragments to Surface Modified Upconversion Nanoparticles for an Initial in Vivo Molecular Imaging Proof of Principle Approach. Int J Mol Sci 13: 4153-4167. [IF 2.464] Abstract
    5. Horst SA, Hoerr V, Beineke A, Kreis C, Tuchscherr L, Kalinka J, Lehne S, Schleicher I, Köhler G, Fuchs T, Raschke MJ, Rohde M, Peters G, Faber C, Löffler B, Medina E (2012) A novel mouse model of Staphylococcus aureus chronic osteomyelitis that closely mimics the human infection: an integrated view of the disease pathogenesis.  Am J Pathol 181: 1206-1214. [IF 4.522] Abstract
    6. Hugenberg V, Breyholz HJ, Riemann B, Hermann S, Schober O, Schäfers M, Gangadharmath U, Mocharla V, Kolb H, Walsh J, Zhang W, Kopka K, Wagner S (2012) A new class of highly potent matrix metalloproteinase inhibitors based on triazole-substituted hydroxamates: (radio)synthesis and in vitro and first in vivo evaluation. J Med Chem 55: 4714-4727. [IF 5.614] Abstract
    7. Strobel K, Hoerr V, Schmid F, Wachsmuth L, Löffler B, Faber C (2012) Early detection of lung inflammation: exploiting T1-effects of iron oxide particles using UTE MRI. Magn Reson Med 68: 1924-1931. [IF 2.060] Abstract
    8. Vrachimis A, Hermann S, Máthé D, Schober O, Schäfers M (2012) Systematic evaluation of 99mTc-tetrofosmin versus 99mTc-sestamibi to study murine myocardial perfusion in small animal SPECT/CT. EJNMMI Res 2: 21. [IF 5.114] Abstract

  • Publications (2006 - 2011)

    The list below is the output of the former independent Core Units CarTel, ECHO, OPTI, SAMRI and SmAP, which with the exception of CarTel, merged to form PIX.2011
    1. Bunk EC, Stelzer S, Hermann S, Schäfers M, Schlatt S, Schwamborn JC (2011) Cellular organization of adult neurogenesis in the Common Mar­moset. Aging Cell 10: 28-38. [IF 7,14] Abstract
    2. Kentrup D, Reuter S, Schnöckel U, Grabner A, Edemir B, Pavenstädt H, Schober O, Schäfers M, Schlatter E, Büssemaker E (2011) Hydroxyfasudil-mediated inhibition of ROCK1 and ROCK2 improves kidney function in rat renal acute ischemia-reperfusion injury. PLoS One 6: e26419. [IF 4,41]Abstract
    3. Milberg P, Klocke R, Frommeyer G, Quang TH, Dieks K, Stypmann J, Osada N, Kuhlmann M, Fehr M, Milting H, Nikol S, Waltenberger J, Breithardt G, Eckardt L (2012) G-CSF therapy reduces myocardial repolarization reserve in the presence of increased arteriogenesis, angiogenesis and connexin 43 expression in an experimental model of pacing-induced heart failure. Basic Res Cardiol 106: 995-1008. [IF 6,13] Abstract
    4. Seidler DG, Mohamed NA, Bocian C, Stadtmann A, Hermann S, Schäfers K, Schäfers M, Iozzo RV, Zarbock A, Götte M (2011) The role for decorin in delayed-type hypersensitivity. J Immunol 187: 6108-6119. [IF 5,74] Abstract
    1. Breyholz HJ, Wagner S, Faust A, Riemann B, Höltke C, Hermann S, Schober O, Schäfers M, Kopka K (2010) Radiofluorinated pyrimidine-2,4,6-triones as molecular probes for noninvasive MMP-targeted imaging. ChemMedChem 5: 777-789. [IF 3,23] Abstract
    2. Büscher K, Judenhofer MS, Kuhlmann MT, Hermann S, Wehrl HF, Schäfers KP, Schäfers M, Pichler BJ, Stegger L (2010) Isochronous assessment of cardiac metabolism and function in mice using hybrid PET/MRI. J Nucl Med 51: 1277-1284. [IF 6,42] Abstract
    3. Di Marco GS, Reuter S, Kentrup D, Ting L, Ting L, Grabner A, Jacobi AM, Pavenstadt H, Baba HA, Tiemann* K, Brand* M (2010) Cardioprotective effect of calcineurin inhibition in an animal model of renal disease. Eur Heart J 32: 1935-1945. [IF 9,80] *equal contribution Abstract
    4. Dreischaluck J, Schwoppe C, Spieker T, Kessler T, Tiemann K, Liersch R, Schliemann C, Kreuter M, Kolkmeyer A, Hintelmann H, Mesters RM, Berdel WE (2010) Vascular infarction by subcutaneous application of tissue factor targeted to tumor vessels with NGR-peptides: activity and toxicity profile. Int J Oncol 37: 1389-1397. [IF 2,45] Abstract
    5. Eisenblätter M, Höltke C, Persigehl T, Bremer C (2010) Optical techniques for the molecular imaging of angiogenesis. Eur J Nucl Med Mol Imaging 37 Suppl 1: S127-137. (Review) [IF 4,53] Abstract
    6. Fabritz L, Damke D, Emmerich M, Kaufmann SG, Theis K, Blana A, Fortmüller L, Laakmann S, Hermann S, Aleynichenko E, Steinfurt J, Volkery D, Riemann B, Kirchhefer U, Franz MR, Breithardt G, Carmeliet E, Schäfers M, Maier SK, Carmeliet P, Kirchhof P (2010) Autonomic modulation and antiarrhythmic therapy in a model of long QT syndrome type 3. Cardiovasc Res 87: 60-72. [IF 5,80] Abstract
    7. Larmann J, Frenzel T, Hahnenkamp A, Herzog C, Lorenz A, Steinbicker AU, Calmer S, Harendza T, Schmitz M, Echtermeyer F, Hildebrand R, Bremer C, Theilmeier G (2010) In vivo fluorescence-mediated tomography for quantification of urokinase receptor-dependent leukocyte trafficking in inflammation. Anesthesiology 113: 610-618. [IF 5,35] Abstract
    8. Law MP, Schäfers K, Kopka K, Wagner S, Schober O, Schäfers M (2010) Molecular imaging of cardiac sympathetic innervation by 11C-mHED and PET: from man to mouse? J Nucl Med 51: 1269-1276. [IF 6,42] Abstract
    9. Law MP, Wagner S, Kopka K, Renner C, Pike VW, Schober O, Schäfers M (2010) Preclinical evaluation of an 18F-labelled beta1-adrenoceptor selective radioligand based on ICI 89,406. Nucl Med Biol 37: 517-526. [IF 6,42] Abstract
    10. Reuter S, Schnöckel U, Edemir B, Schröter R, Kentrup D, Pavenstädt H,Schober O, Schlatter E, Gabriëls G, Schäfers M (2010) Potential of noninvasive serial assessment of acute renal allograft rejection by 18F-FDG PET to monitor treatment efficiency. J Nucl Med 51: 1644-1652. [IF 6,42] Abstract
    11. Schäfers M, Schober O, Hermann S (2010) Matrix-metalloproteinases as imaging targets for inflammatory activity in atherosclerotic plaques. J Nucl Med 51: 663-666. (Review) [IF 6,42] Abstract
    12. Schnöckel U, Hermann S, Stegger L, Law M, Kuhlmann M, Schober O, Schäfers K, Schäfers M (2010) Small-animal PET: A promising, non-invasive tool in pre-clinical research. Eur J Pharm Biopharm 74: 50-54. [IF 3,15] Abstract
    1. Bunck AC, Engelen MA, Schnackenburg B, Furkert J, Bremer C, Heindel W, Stypmann J, Maintz D (2009) Feasibility of Functional Cardiac MR Imaging in Mice Using A Clinical 3 Tesla Whole Body Scanner. Invest Radiology 44: 749-756. [IF 5,28] Abstract
    2. Eisenblätter M, Ehrchen J, Varga G, Sunderkötter C, Heindel W, Roth J, Bremer C and Wall A (2009) In vivo optical imaging of cellular inflammatory response in granuloma formation using fluorescence-labeled macrophages. J Nucl Med 50: 1676-1682. [IF 6,66] Abstract
    3. Faust A, Waschkau B, Waldeck J, Höltke C, Breyholz HJ, Wagner S, Kopka K, Schober O, Heindel W, Schäfers M and Bremer C (2009) Synthesis and Evaluation of a Novel Hydroxamate Based Fluorescent Photoprobe for Imaging of Matrix Metalloproteinases. Bioconjug Chem 20: 904-912. [IF 4,58] Abstract
    4. Höltke C, Law MP, Wagner S, Kopka K, Faust A, Breyholz HJ, Schober O, Bremer C, Riemann B, Schäfers M (2009) PET-compatible endothelin receptor radioligands: synthesis and first in vitro and in vivo studies. Bioorg Med Chem 17: 7197-7208. [IF 3,07] Abstract
    5. Höltke C, Waldeck J, Kopka K, Heindel W, Schober O, Schäfers M and Bremer C (2009) Biodistribution of a nonpeptidic fluorescent endothelin A receptor imaging probe. Mol Imaging 8: 27-34. [IF 3,32] Abstract
    6. Kuhn M, Volker K, Schwarz K, Carbajo-Lozoya J, Flogel U, Jacoby C, Stypmann J, van Eickels M, Gambaryan S, Hartmann M, Werner M, Wieland T, Schrader J, Baba HA (2009) The natriuretic peptide/guanylyl cyclase-A system functions as a stress-responsive regulator of angiogenesis in mice. J Clin Invest 119: 2019-2030. [IF 16,55] Abstract
    7. Schnöckel U, Hermann S, Stegger L, Law M, Kuhlmann M, Schober O, Schäfers K, Schäfers M (2009). Small-animal PET: A promising, non-invasive tool in pre-clinical research. Eur J Pharm Biopharm 74: 50-54 [IF 3,34] Abstract
    8. Stypmann J, Engelen MA, Troatz C, Rothenburger M, Eckardt L, Tiemann K (2009) Echocardiographic assessment of global left ventricular function in mice. Lab Animals 43: 127-137. [IF 1,07] Abstract
    9. Wagner S, Breyholz HJ, Höltke C, Faust A, Schober O, Schäfers M, Kopka K (2009) A new (18)F-labelled derivative of the MMP inhibitor CGS 27023A for PET: Radiosynthesis and initial small-animal PET studies. Appl Radiat Isot 67: 606-610. [IF 1,11] Abstract
    10. Weberpals M, Hermes M, Hermann S, Kummer MP, Terwel D, Semmler A, Berger M, Schäfers M, Heneka MT (2009) NOS2 gene deficiency protects from sepsis-induced long-term cognitive deficits. J Neurosci 29: 14177-14184. [IF 7,45] Abstract
    1. Levkau B, Schafers M, Wohlschlaeger J, von Wnuck LK, Keul P, Hermann S, Kawaguchi N, Kirchhof P, Fabritz L, Stypmann J, Stegger L, Flogel U, Schrader J, Fischer JW, Hsieh P, Ou YL, Mehrhof F, Tiemann K, Ghanem A, Matus M, Neumann J, Heusch G, Schmid KW, Conway EM, Baba HA (2008) Survivin determines cardiac function by controlling total cardiomyocyte number. Circulation 117: 1583-1593. [IF 12,7]Abstract
    2. Schnöckel U, Reuter S, Stegger L, Schlatter E, Schäfers KP, Hermann S, Schober O, Gabriëls G, Schäfers M (2008) Dynamic 18F-fl uoride small animal PET to noninvasively assess renal function in rats. Eur J Nucl Med Mol Imaging 35: 2267-2274. [IF 4,1] Abstract
    3. Semmler A, Hermann S, Mormann F, Weberpals M, Paxian SA, Okulla T, Schäfers M, Kummer MP, Klockgether T, Heneka MT (2008) Sepsis causes neuroinflammation and concomitant decrease of cerebral metabolism. J Neuroinflamm 15: 38 [Kein IF] Abstract
    4. Stelljes M, Hermann S, Albring J, Köhler G, Löffl er M, Franzius C, Poremba C, Schlösser V, Volkmann S, Opitz C, Bremer C, Kucharzik T, Silling G, Schober O, Berdel WE, Schäfers M, Kienast J (2008) Clinical molecular imaging in intestinal graft-versus-host disease: mapping of disease activity, prediction, and monitoring of treatment efficiency by positron emission tomography. Blood 111: 2909-2918. [IF 10,9] Abstract
    5. Waldeck J, Häger F, Höltke C, Lanckohr C, von Wallbrunn A, Torsello G, Heindel W, Theilmeier G, Schäfers M, Bremer C (2008) Fluorescence reflectance imaging of macrophage-rich atherosclerotic plaques using an alphavbeta3 integrin-targeted fluorochrome. J Nucl Med 49: 1845-1851. [IF 5,9] Abstract
    1. Breyholz HJ, Wagner S, Levkau B, Schober O, Schäfers M, Kopka K (2007) A 18F-radiolabeled analogue of CGS 27023A as a potential agent for assessment of matrix-metalloproteinase activity in vivo. Q J Nucl Med Mol Imaging 51: 24-32. [IF 2,1] Abstract
    2. Ghanem A, Troatz, C, Elhafi N, Dewald O, Heeschen C, Nickenig G, Stypmann J, Tiemann K (2007) Quantitation of Myocardial Borderzone using 3-D-Echocardiography after Chronic Infarction in Rats - Incremental Value of low-dose Dobutamine. Ultrasound Med Biol 34: 559-566. [IF 2,0] Abstract
    3. Kirchhof P, Klimas J, Fabritz L, Zwiener M, Jones LR, Schäfers M, Hermann S, Boknik P, Schmitz W, Breithardt G, Kirchhefer U, Neumann J (2007) Stress and high heart rate provoke ventricular tachycardia in mice expressing triadin. J Mol Cell Cardiol 42: 962-71. [IF 4,9] Abstract
    4. Spira D, Stypmann J, Tobin DJ, Petermann I, Mayer C, Hagemann S, Vasijeva O, Günther T, Schüle R, Peters C, Reinheckel T (2007) Cell type - specific functions of the lysosomal protease Cathepsin L in the heart. J Biol Chem 282: 37045-37052. [IF 5,8]Abstract
    1. Kirchhof P, Fabritz L, Zwiener M, Witt H, Schäfers M, Zellerhoff S, Paul M, Athai T, Hiller KH, Baba HA, Breithardt G, Ruiz P, Wichter T, Levkau B (2006) Age- and Training-Dependent Development of Arrhythmogenic Right Ventricular Cardiomyopathy in Heterozygous Plakoglobin-Deficient Mice. Circulation 114: 1799-1806. [IF 11,6] Abstract
    2. Kuhlmann, MT, Kirchhof P, Klocke R, Hasib L, Stypmann J, Fabritz L, Stelljes M, Tian W, Zwiener M, Mueller M, Kienast J, Breithardt G, Nikol S (2006) G-CSF/SCF reduces inducible arrhythmias in the infarcted heart potentially via increased connexin43 expression and arteriogenesis. J Exp Med 203: 87-97. [IF 14,6] Abstract
    3. Petermann I, Mayer C, Stypmann J, Biniossek ML, Tobin DJ, Engelen MA, Dandekar T, Grune T, Schild L, Peters C, Reinheckel T (2006) Lysosomal, cytoskeletal, and metabolic alterations in cardiomyopathy of cathepsin L knockout mice. FASEB 20: 1266-1278. [IF 6,8] Abstract
    4. Stypmann J, Engelen MA, Epping C, van Rijen HVM, Milberg P, Bruch C, Breithardt G, Tiemann K, Eckardt L (2006) Age and gender related reference values for transthoracic Doppler-echocardiography in the anesthetized CD1 mouse. International J Cardiovasc Imaging 22: 353-362. [IF 0,8] Abstract
    5. Stypmann J, Janssen PML, Prestle J, Engelen MA, Kögler H, Lüllman-Rauch R, Eckardt L, von Figura K, Landgrebe Jobst, Saftig P (2006) LAMP-2 deficient mice show depressed cardiac contractile function without significant changes in calcium handling. Basic Res Cardiol 101: 281-291. [IF 3,0] Abstract
    6. Kopka K, Faust A, Keul P, Wagner S, Breyholz HJ, Höltke C, Schober O, Schäfers M, Levkau B (2006) 5-pyrrolidinylsulfonyl isatins as a potential tool for the molecular imaging of caspases in apoptosis. J Med Chem 49: 6704-6715. [IF 4,9] Abstract
    7. Stegger L, Hoffmeier AN, Schäfers KP, Hermann S, Schober O, Schäfers MA, Theilmeier G (2006) Accurate non-invasive measurement of infarct size in mice with high resolution positron emission tomography. J Nucl Med 47: 1837-1844. [IF 4,7] Abstract
    8. Theilmeier G, Schmidt C, Herrmann J, Keul P, Schäfers M, Herrgott I, Mersmann J, Larmann J, Hermann S, Stypmann J, Schober O, Hildebrand R, Schulz R, Heusch G, Haude M, von Wnuck Lipinski K, Herzog C, Schmitz M, Erbel R, Chun J, Levkau B (2006) High-density lipoproteins and their constituent sphingosine-1-phosphate directly protect the heart against ischemia/reperfusion injury in vivo via the S1P3 lysophospholipid receptor. Circulation 114: 1403-1409. [IF 11,6] Abstract
    9. von Wallbrunn A, Höltke C, Zühlsdorf M, Heindel W, Schäfers M, Bremer C (2006) In vivo imaging of integrin alphanubeta(3) expression using fluorescence-mediated tomography. Eur J Nucl Med Mol Imaging 34: 745-754. [IF 3,9] Abstract
    10. Wagner S, Breyholz HJ, Faust A, Höltke C, Levkau B, Schober O, Schäfers M, Kopka K (2006) Molecular Imaging of Matrix Metalloproteinases in vivo using small molecule inhibitors for SPECT and PET. Curr Med Chem 13: 2819-2838. [IF 4,9] Abstract