*          co-corresponding author

**        equal contributions



  1. Bayraktar S**, Nehrig J**, Menis E, Karli K, Janning A, Struk T, Halbritter J, Michgehl U, Krahn MP, Schuberth CE*, Pavenstädt H*, Wedlich-Söldner R* (2020). A Deregulated Stress Response Underlies Distinct INF2-Associated Disease Profiles. J Am Soc Nephrol, doi: 10.1681/ASN.2019111174.
  1. Skryabin BV, Kummerfeld DM, Gubar L, Seeger B, Kaiser H, Stegemann A, Roth J, Meuth SG, Pavenstädt H, Sherwood J, Pap T, Wedlich-Söldner R, Sunderkötter C, Schwartz YB, Brosius J, Rozhdestvensky TS (2020) Pervasive head-to-tail insertions of DNA templates mask desired CRISPR-Cas9-mediated genome editing events. Sci Adv. 6: eaax2941.


  1. Mewes M, Lenders M, Stappers F, Scharnetzki D, Nedele J, Fels J, Wedlich-Söldner R, Brand SM, Schmitz B, Brand E. (2019) Soluble adenylyl cyclase (sAC) regulates calcium signaling in the vascular endothelium. FASEB J. 33: 13762-13774.
  1. Mietkowska M, Schuberth C, Wedlich-Söldner R, Gerke V. (2019). Actin dynamics during Ca2+-dependent exocytosis of endothelial Weibel-Palade bodies. Biochim Biophys Acta Mol Cell Res. 2019 Jul;1866(7):1218-1229. doi: 10.1016/j.bbamcr.2018.11.010.
  1. Dlugos CP, Picciotto C, Lepa C, Krakow M, Stöber A, Eddy ML, Weide T, Jeibmann A, P Krahn M, Van Marck V, Klingauf J, Ricker A, Wedlich-Söldner R, Pavenstädt H, Klämbt C, George B. (2019). Nephrin Signaling Results in Integrin β1 Activation. J Am Soc Nephrol. 2019
  1. Jun;30(6):1006-1019. doi: 10.1681/ASN.2018040362.Busto JV, Wedlich-Söldner R. (2019). Integration Through Separation - The Role of Lateral Membrane Segregation in Nutrient Uptake. Front Cell Dev Biol. 2019 Jun 25;7:97. doi: 10.3389/fcell.2019.00097.


  1. Wedlich-Soldner, R. and Betz, T. (2018). Self-organization: the fundament of cell biology. Philos Trans R Soc Lond B. 2018 May 26; 373(1747). pii: 20170103. doi: 10.1098/rstb.2017.0103.
  1. Prystopiuk, V., Fels, B., Simon, C. S., Liashkovich, I., Pasrednik, D., Kronlage, C., Wedlich-Soldner, R., Oberleithner, H. and Fels, J. (2018). A two-phase response of endothelial cells to hydrostatic pressure. J Cell Sci. pii:  jcs.206920. doi: 10.1242/jcs.206920.
  1. Busto, J.V., Elting, A., Haase, D., Spira, F., Kuhlman, J., Schäfer-Herte, M. and Wedlich-Soldner, R. (2018). Lateral plasma membrane compartmentalization links protein function and turnover. EMBO J. 37: pii: e99473


  1. Aufschnaiter, R., Wedlich-Soldner, R., Zhang, X. and Hobmayer, B. (2017). Apical and basal epitheliomuscular F-actin dynamics during Hydra bud evagination. Biology Open 6: 1137-1148.
  1. Granado, D., Müller, D., Krausel, V., Kruzel-Davilla, E., Schuberth, C., Eschborn, M., Wedlich-Soldner, R., Skorecki, K., Pavenstädt, H., Michgehl, U. and Weide, T.  (2017). Intracellular APOL1 Risk Variants Cause Cytotoxicity Accompanied by Energy Depletation. J AM Soc Nephrol. 28: 3227-3238.
  1. Horsthemke, M., Bachg, A.C., Groll, K., Moyzio, S., Müther, B., Hemkemeyer, S.A., Wedlich-Soldner, R., Sixt, M., Tacke, S., Bähler, M. and Hanley, P.J. (2017). Multiple roles of filopodial dynamics in particle capture and phagocytosis and phenotypes of Cdc42 and Myo10 deletion.J Biol Chem. 292: 7258-7273.


  1. Wales, P.**,Schuberth, C.E.**, Aufschnaiter, R.**, Fels, J., García-Aguilar, I., Janning, A., Dlugos, C.P., Schäfer-Herte, M., Klingner, C., Wälte, M., Kuhlmann, J., Menis, K., Hockaday Kang, L., Maier, K.C., Hou, W., Russo, A., Higgs, H.N., Pavenstädt, H., Vogl, T., Roth, J., Qualmann, B., Kessels, M.M., Martin, D.E., Mulder, B. and Wedlich-Soldner, R. (2016). Calcium-mediated actin reset (CaAR) mediates acute cell adaptions. Elife 5: e19850.
  1. Zhu, J., Baily, A., Zwiewka, M., Sovero, V., Di Donato, M., Ge, P., Oehri, J., Aryal, B., Hao, P., Linnert, M., Burgardt, N.I., Lücke, C., Weiwad, M., Michel, M., Weiergräber, O.H., Pollmann, S., Azzarello, E., Mancuso, S., Ferro, N., Fukao, Y., Hoffmann, C., Wedlich-Soldner, R., Friml, J., Thomas, C., Geisler, M. (2016). Twisted Dwarf1 Mediates the action of Auxin Transport Inhibitors on Actin Cytoskeleton Dynamics. Plant Cell. 28: 930-48.


  1. Crevenna, A.H., Arciniega, M., Dupont, A., Mizuno, N., Kowalska, K., Lange, O.F., Wedlich-Soldner, R. and Lamb, D.C. (2015). Side-binding proteins modulate actin filament dynamics. Elife 4: e04599.
  1. Schuberth, C. and Wedlich-Soldner, R. (2015). Building a patchwork - The yeast plasma membrane as model to study lateral domain formation. Biochim Biophys Acta 1853: 767-774. 


  1. Klingner, C. **, Cherian, A.V. **, Fels, J., Diesinger, P.M., Aufschnaiter, R., Maghelli, N., Keil, T., Beck, G., Tolić-Nørrelykke, I.M., Bathe, M. and Wedlich-Soldner, R. (2014). Isotropic acto-myosin dynamics promote organization of the apical cell cortex in epithelial cells. J Cell Biol. 207: 107-21.
  1. Wedlich-Soldner, R. (2014). A longer life for yeast with good memory. Dev Cell. 31: 391-2.
  1. Marel, A.K., Zorn, M., Klingner, C., Wedlich-Soldner, R., Frey, E. and Rädler, J.O. (2014). Flow and diffusion in channel-guided cell migration. Biophys J. 107: 1054-64.
  1.  Domínguez-Escobar, J.**, Wolf, D.**, Fritz, G., Höfler, C., Wedlich-Soldner, R. and Mascher, T. (2014). Subcellular localization, interactions and dynamics of the phage-shock protein-like Lia response in Bacillus subtilis. Mol Microbiol. 92: 716-32.
  1. Rueff, A.S., Chastanet, A., Dominguez-Escobar, J., Yao, Z., Yates, J., Prejean, M.V., Delumeau, O., Noirot, P., Wedlich-Soldner, R., Filipe, S.R. and Carballido-López, R. (2014). An early cytoplasmic step of peptidoglycan synthesis is associated to MreB in Bacillus subtilis. Mol Microbiol. 91: 348-62.


  1. Klünder, B.**, Freisinger, T.**, Wedlich-Soldner, R.* and Frey, E.* (2013). GDI-Mediated Cell Polarization in Yeast Provides Precise Spatial and Temporal Control of Cdc42 Signaling, PLoS Comp Biology. 9: e1003396.
  1. Abdelhady, S., Kitambi, S.S., Lundin, V., Aufschnaiter, R., Sekyrova, P., Sinha, I., Lundgren, K.T., Castelo-Branco, G., Linnarsson, S., Wedlich-Soldner, R., Teixeira, A. and Andäng, M. (2013). Erg channel is critical in controlling cell volume during cell cycle in embryonic stem cells. PLoS One 8: e72409.
  1. Freisinger, T. ** Klünder, B. **, Johnson, J., Müller, N., Pichler, G., Beck, G., Costanzo, M., Boone, C., Cerione, R. A., Frey, E.* and Wedlich-Soldner, R.* (2013). Establishment of a robust single axis of cell polarity by coupling multiple positive feedback loops. Nat Commun. 4: 1807.
  1. Crevenna, A.H., Naredi-Rainer, N., Schonichen, A., Dzubiella, J., Barber, D.L., Lamb, D.C., Wedlich-Soldner, R. (2013). Electrostatics control actin filament nucleation and elongation kinetics. J Biol Chem. 288: 12102-13.


  1. Flynn, K.C., Hellal, F., Neukirchen, D., Jacob, S., Tahirovic, S., Dupraz, S., Stern, S., Garvalov, B.K., Gurniak, C., Shaw, A.E., Meyn, L., Wedlich-Soldner, R., Bamburg, J.R., Small, J.V., Witke, W., Bradke, F. (2012). ADF/Cofilin-Mediated Actin Retrograde Flow Directs Neurite Formation in the Developing Brain. Neuron 76: 1091-107.
  1. Huang, J., Huang, Y., Yu, H., Subramanian, D., Padmanabhan, A., Thadani, R., Tao, Y., Tang, X., Wedlich-Soldner, R., Balasubramanian, M.K. (2012). Nonmedially assembled F-actin cables incorporate into the actomyosin ring in fission yeast. J Cell Biol. 199: 831-47.
  1. Fraccaroli, A., Franco, C.A., Rognoni, E., Neto, F., Rehberg, M., Aszodi, A., Wedlich-Soldner, R., Pohl, U., Gerhardt, H., Montanez, E. (2012). Visualization of endothelial actin cytoskeleton in the mouse retina. PLoS One 7: e47488.
  1. Mueller, N.S., Wedlich-Soldner, R. and Spira, F. (2012). From mosaic to patchwork: matching lipids and proteins in membrane organization. Mol Membr Biol.29: 186-96.
  1. Schachtner, H., Li, A., Stevenson, D., Calaminus, S.D., Thomas, S.G., Watson, S.P., Sixt, M., Wedlich-Soldner, R., Strathdee, D., Machesky, L.M. (2012). Tissue inducible Lifeact expression allows visualization of actin dynamics in vivo and ex vivo. Eur J Cell Biol. 91: 923-9.
  1. Spira, F.**, Dominguez-Escobar, J.**, Mueller, N.S., Wedlich-Soldner, R. (2012). Visualization of cortex organization and dynamics in microorganisms, using Total Internal Reflection Fluorescence microscopy. J Vis Exp. 63: e3982.
  1. Spira, F.**, Mueller, N.S.**, Beck, G., von Olshausen, P., Beig, J., Wedlich-Soldner, R. (2012). Patchwork organization of the yeast plasma membrane into numerous coexisting domains. Nat Cell Biol.14: 640-8.
  1. Crevenna, A. H., Naredi-Rainer, N., Lamb, D.C., Wedlich-Soldner, R., Dzubiella, J. (2012). Effects of Hofmeister Ions on the a -Helical Structure of Proteins. Biophys J. 102: 907-15.


  1. Tønnesen, J., Nadringy, F., Willig, K.I., Wedlich-Soldner, R., Nägerl, U.V. (2011). Two-Color STED Microscopy of Living Synapses Using A Single Laser-Beam Pair. Biophys J. 101: 2545-52.
  1. Freisinger, T. and Wedlich-Soldner, R.(2011).Phosphatidylserine promotes polar Cdc42 localization.Nat Cell Biol. 13: 1387-8.
  1. Wen, P.J., Osborne, S.L., Zanin, M., Low, P.C., Wang, H.T., Schoenwaelder, S.M., Jackson, S.P., Wedlich-Soldner, R., Vanhaesebroeck, B., Keating, D.J., Meunier, F.A. (2011). Phosphatidyl-inositol(4,5)bisphosphate coordinates an actin-mediated mobilization and translocation of secretory vesicles to the plasma membrane of chromaffin cells. Nature Communications 2: 491.
  1. Chesarone-Cataldo, M., Guérin, C., Yu, J.H., Wedlich-Soldner, R., Blanchoin, L., Goode, B.L. (2011). The Myosin passenger protein smy1 controls actin cable structure and dynamics by acting as a formin damper. Dev Cell. 21: 217-30.
  1. Domínguez-Escobar,J., Chastanet, A., Crevenna, A. H.,Fromion, V., Wedlich-Soldner, R.* and Carballido-López, R.* (2011). Processive Movement of MreB-Associated Cell Wall Biosynthetic Complexes in Bacteria. Science 333: 225-8.
  1. Yu, H. and Wedlich-Soldner, R. Cortical actin dynamics: Generating randomness by formin(g) and moving (2011). BioArchitecture 1: 165-168.
  1. Yu, J. H., Crevenna, A. H., Bettenbühl, M., Freisinger, T., Wedlich-Soldner, R. (2011). Cortical actin dynamics driven by formins and myosin V. J Cell Sci. 124: 1533-41.


  1. Riedl, J., Flynn, K.C., Raducanu, A., Gärtner, F., Beck, G., Bösl, M., Bradke, F., Massberg, S., Aszodi, A., Sixt, M. and Wedlich-Soldner, R. (2010). Lifeact-mice for studying F-actin dynamics. Nature Methods 7: 168-9.
  1. Li, R., Wedlich-Soldner, R. (2009). Bem1 complexes and the complexity of yeast cell polarization. Curr Biol. 19: R194-5.


  1. Riedl, J., Crevenna, A.H., Kessenbrock, K., Yu, J.H., Neukirchen, D., Bista, M., Bradke, F., Jenne, D., Holak, T.A., Werb, Z., Sixt, M. and Wedlich-Soldner, R. (2008). Lifeact - a versatile marker for the visualization of F-actin. Nature Methods 5: 605-7.
  1. Lämmermann, T., Bader, B.L., Monkley, S.J., Worbs, T., Wedlich-Soldner, R., Hirsch, K., Keller, M., Förster, R., Critchley, D.R., Fässler, R. and Sixt, M. (2008). Rapid leukocyte migration by integrin-independent flowing and squeezing. Nature 453: 51-5.
  1. Wedlich-Soldner, R. and Li, R. (2008). Yeast and fungal morphogenesis from an evolutionary perspective. Semin Cell Dev Biol. 19: 224-33.
  1. Marco, E.**, Wedlich-Soldner, R.**, Li, R., Altschuler, S. and Wu, L. (2007). Endocytosis optimizes the dynamic localization of membrane proteins that regulate cortical polarity. Cell 129: 411-22.


  1. Wedlich-Soldner, R. and Li, R. (2004). Closing the loops: New insights into the role and regulation of actin during cell polarization. Exp Cell Res. 301:8-15.
  1. Wedlich-Soldner, R., Wai, S.C., Schmidt, T. and Li, R. (2004). Robust cell polarity is a dynamic state established by coupling transport and GTPase signaling. J Cell Biol. 166: 889-900.
  1. Wedlich-Soldner, R. and Li, R. (2003). Spontaneous cell polarization: undermining determinism. Nat Cell Biol.5: 267-70.
  1. Wedlich-Soldner, R., Altschuler, S., Wu, L. and Li, R. (2003). Spontaneous cell polarization through actomyosin-based delivery of the Cdc42 GTPase. Science 299: 1231-5.


  1. Wedlich-Soldner, R., Straube, A., Friedrich, M.W., Steinberg, G. (2002). A balance of KIF1A-like kinesin and dynein organizes early endosomes in the fungus Ustilago maydis. EMBO J. 21: 2946-57.
  1. Wedlich-Soldner, R., Schulz, I., Straube, A., Steinberg, G. (2002). Dynein supports motility of endoplasmic reticulum in the fungus Ustilago maydis. Mol Biol Cell. 13: 965-77.
  1. Straube, A., Enard, W., Berner, A., Wedlich-Soldner, R., Kahmann, R. and Steinberg, G. (2001). A split motor domain in a fungal cytoplasmic dynein. EMBO J. 20: 5091-100.
  1. Steinberg, G., Wedlich-Soldner, R., Brill, M. and Schulz, I. (2001). Microtubules in the fungal pathogen Ustilago maydis are highly dynamic and determine cell polarity. J Cell Sci 114: 609-22.
  1. Wedlich-Soldner, R., Bölker, M., Kahmann, R. and Steinberg, G. (2000). A putative endosomal t-SNARE links exo- and endocytosis in the phytopathogenic fungus Ustilago maydis. EMBO J. 19: 1974-86.