The aim of our research is to better understand the dynamics of the immune system in the context of human clinical disease. The main focus is to directly visualize the behavior of immune cells during inflammation, infection and resolution by using cutting edge technology, including laser-scanning confocal and 2-photon microscopy. Imaging complex cellular behaviors in real time, both in vitro and in vivo, provides a unique window into these dynamic processes (Jorch & Deppermann, Front Cell Dev Biol., 2021). We focus on monocytes, macrophages and neutrophils in different organs during S. aureus and E. coli infections or diseases like Familial Mediterranean Fever.

Here you can find out more about the different projects.