Curriculum Vitae

2018-today       PhD: Institute for Molecular Virology, University Münster

2011-2017         Studies: Medical Biotechnology, Rostock University

Memberships and other activities:

• Member of the German Society of Virology (GfV)
• Member of the Microbiology Society (UK)
• German Research Platform for Zoonoses

Project

My PhD project addresses post-translational modifications of the influenza A Virus polymerase. I am investigating the influence of site-specific ubiquitination on the function, localization and conformation of the polymerase complex.

Methods

Mass spectrometry, cell culture, cloning, generation of recombinant viruses, knockdown, reporter-based assays, immune fluorescence analyses, immune precipitation, western blotting, protein structure analyses, BSL3. Software: PyMOL, ChimeraX, Fiji-ImageJ

Publication and awards

Günl, F., Mecate-Zambrano, A., Rehländer, S., Hinse, S., Ludwig, S., and Brunotte, L. (2021) Shooting at a Moving Target-Effectiveness and Emerging Challenges for SARS-CoV-2 Vaccine Development, Vaccines (Basel)9.

Krischuns Tim, Günl Franziska, Henschel Lea, Binder Marco, Willemsen Joschka, Schloer Sebastian, Rescher Ursula, Gerlt Vanessa, Zimmer Gert, Nordhoff Carolin, Ludwig Stephan, Brunotte Linda Phosphorylation of TRIM28 Enhances the Expression of IFN-β and Proinflammatory Cytokines During HPAIV Infection of Human Lung Epithelial Cells. Frontiers in Immunology (Vol. 9, 2018). DOI=10.3389/fimmu.2018.02229