Selected publications since 2000


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2018      2017      2016      2015      2014     2013     2012     2011    2010     2009     2008      2007      2006      2005      2004      2003      2002      2001      2000     

 



click here for complete publication list in pubmed.

 

2018

Heitzig N, Kühnl A., Grill D, Ludewig K, Schloer S, Galla HJ, Grewal T, Gerke V, Rescher U
Cooperative binding promotes demand-driven recruitment of AnxA8 to cholesterol-containing membranes.
Biochim Biophys Acta. 2018 Jan 3;1863(4):349-358. doi: 10.1016/j.bbalip.2018.01.001. [Epub ahead of print] PMID: 290306076

2017

Steinbacher T, Kummer D, Ebnet K.
Junctional adhesion molecule-A: functional diversity through molecular promiscuity.
Cell Mol Life Sci. 2017 Dec 14. doi: 10.1007/s00018-017-2729-0. [Epub ahead of print] Review.
PMID:  29238845

Boye TL, Maeda K, Pezeshkian W, Sønder SL, Haeger SC, Gerke V, Simonsen AC, Nylandsted J.
Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair.
Nat Commun. 2017 Nov 20;8(1):1623. doi: 10.1038/s41467-017-01743-6.
PMID: 29158488

Ebnet K.
Junctional Adhesion Molecules (JAMs): Cell Adhesion Receptors With Pleiotropic Functions in Cell Physiology and Development.
Physiol Rev. 2017 Oct 1;97(4):1529-1554. doi: 10.1152/physrev.00004.2017. Review.
PMID: 28931565

Hakobyan D, Gerke V, Heuer A.
Modeling of annexin A2-Membrane interactions by molecular dynamics simulations.
PLoS One. 2017 Sep 22;12(9):e0185440. doi: 10.1371/journal.pone.0185440. eCollection 2017.
PMID: 28937994

de Vries WC, Grill D, Tesch M, Ricker A, Nüsse H, Klingauf J, Studer A, Gerke V, Ravoo BJ.
Reversible Stabilization of Vesicles: Redox-Responsive Polymer Nanocontainers for Intracellular Delivery.
Angew Chem Int Ed Engl. 2017 Aug 1;56(32):9603-9607. doi: 10.1002/anie.201702620. Epub 2017 Jun 9.
PMID: 28485535

Ebnet K, Kummer D, Steinbacher T, Singh A, Nakayama M, Matis M.
Regulation of cell polarity by cell adhesion receptors.
Semin Cell Dev Biol. 2017 Jul 22. pii: S1084-9521(17)30188-X. doi: 10.1016/j.semcdb.2017.07.032. [Epub ahead of print] Review.
PMID: 28739340

Biesemann A, Gorontzi A, Barr F, Gerke V.
Rab35 protein regulates evoked exocytosis of endothelial Weibel-Palade bodies.
J Biol Chem. 2017 Jul 14;292(28):11631-11640. doi: 10.1074/jbc.M116.773333. Epub 2017 May 31.
PMID: 28566286

Lueck K, Carr AF, Stampoulis D, Gerke V, Rescher U, Greenwood J, Moss SE.
Regulation of retinal pigment epithelial cell phenotype by Annexin A8.
Sci Rep. 2017 Jul 5;7(1):4638. doi: 10.1038/s41598-017-03493-3.
PMID: 28680125

Chehab T, Santos NC, Holthenrich A, Koerdt SN, Disse J, Schuberth C, Nazmi AR, Neeft M, Koch H, Man KNM, Wojcik SM, Martin TFJ, van der Sluijs P, Brose N, Gerke V.
A novel Munc13-4/S100A10/annexin A2 complex promotes Weibel-Palade body exocytosis in endothelial cells.
Mol Biol Cell. 2017 Jun 15;28(12):1688-1700. doi: 10.1091/mbc.E17-02-0128. Epub 2017 Apr 27.
PMID: 28450451

Koerdt SN, Gerke V.
Annexin A2 is involved in Ca2+-dependent plasma membrane repair in primary human endothelial cells.
Biochim Biophys Acta. 2017 Jun;1864(6):1046-1053. doi: 10.1016/j.bbamcr.2016.12.007. Epub 2016 Dec 9.
PMID: 27956131

Schulze U, Vollenbröker B, Kühnl A, Granado D, Bayraktar S, Rescher U, Pavenstädt H, Weide T.
Cellular vacuolization caused by overexpression of the PIKfyve-binding deficient Vac14L156R is rescued by starvation and inhibition of vacuolar-ATPase.
Biochim Biophys Acta. 2017 May;1864(5):749-759. doi: 10.1016/j.bbamcr.2017.02.012. Epub 2017 Feb 16.
PMID: 28216340

Drücker P, Rühling A, Grill D, Wang D, Draeger A, Gerke V, Glorius F, Galla HJ.
Imidazolium Salts Mimicking the Structure of Natural Lipids Exploit Remarkable Properties Forming Lamellar Phases and Giant Vesicles.
Langmuir. 2017 Feb 14;33(6):1333-1342. doi: 10.1021/acs.langmuir.6b03182. Epub 2016 Dec 9.
PMID:  27935708

Heitzig N, Brinkmann BF, Koerdt SN, Rosso G, Shahin V, Rescher U.
Annexin A8 promotes VEGF-A driven endothelial cell sprouting.
Cell Adh Migr. 2017 May 4;11(3):275-287. doi: 10.1080/19336918.2016.1264559. Epub 2017 Jan 6.
PMID: 28060564

 

2016

 

Gerke V.
Annexins A2 and A8 in endothelial cell exocytosis and the control of vascular homeostasis.
Biol Chem. 2016 Oct 1;397(10):995-1003. doi: 10.1515/hsz-2016-0207.


Rescher U, Grewal T.
Highlight: annexins in health and disease
Biol Chem. 2016 Oct 1;397(10):947-8. doi: 10.1515/hsz-2016-0264. No abstract available.


Kuehnl A, Musiol A, Raabe CA, Rescher U.
Emerging functions as host cell factors - an encyclopedia of annexin-pathogen interactions.
Biol Chem. 2016 Oct 1;397(10):949-59. doi: 10.1515/hsz-2016-0183.


Fededa JP, Esk C, Mierzwa B, Stanyte R, Yuan S, Zheng H, Ebnet K, Yan W, Knoblich JA, Gerlich DW.
MicroRNA-34/449 controls mitotic spindle orientation during mammalian cortex development.
EMBO J. 2016 Oct 5. pii: e201694056.
 

Squarr AJ, Brinkmann K, Chen B, Steinbacher T, Ebnet K, Rosen MK, Bogdan S.
Fat2 acts through the WAVE regulatory complex  to drive collective cell migration during tissue rotation
J Cell Biol. 2016 Mar 28;212(7):883. doi: 10.1083/jcb.20150808103082016c. Epub 2016 Mar 21. No abstract available.


Brinkmann BF, Steinbacher T, Hartmann C, Kummer D, Pajonczyk D, Mirzapourshafiyi F, Nakayama M, Weide T, Gerke V, Ebnet K.
VE-cadherin interacts with cell polarity protein Pals1 to regulate vascular lumen formation.
Mol Biol Cell. 2016 Sep 15;27(18):2811-21. doi: 10.1091/mbc.E16-02-0127. Epub 2016 Jul 27.
 

Shabardina V, Kramer C, Gerdes B, Braunger J, Cordes A, Schäfer J, Mey I, Grill D, Gerke V, Steinem C.
Mode of Ezrin-Membrane Interaction as a Function of PIP2 Binding and Pseudophosphorylation
Biophys J. 2016 Jun 21;110(12):2710-9. doi: 10.1016/j.bpj.2016.05.009.
 

Tuncay H, Ebnet K.
Cell adhesion molecule control of planar spindle orientation.
Cell Mol Life Sci. 2016 Mar;73(6):1195-207. doi: 10.1007/s00018-015-2116-7. Epub 2015 Dec 23. Review.

 
Franz J, Brinkmann BF, König M, Hüve J, Stock C, Ebnet K, Riethmüller C.
Nanoscale Imaging Reveals a Tetraspanin-CD9 Coordinated Elevation of Endothelial ICAM-1 Clusters.
PLoS One. 2016 Jan 5;11(1):e0146598. doi: 10.1371/journal.pone.0146598. eCollection 2016.

 

2015

 

Tuncay H., B.F. Brinkmann and K. Ebnet (2015).
Mitotic spindle orientation: JAM-A can fix it.
Cell Cycle 14(24):3773-4. doi: 10.1080/15384101.2015.1105696.

 

Schwickert A., E. Weghake, K. Brüggemann, A. Engbers, B.F. Brinkmann, B. Kemper, J. Seggewiß, C. Stock, K. Ebnet, L. Kiesel, C. Riethmüller and M. Götte (2015).
microRNA miR-142-3p inhibits breast cancer cell invasiveness by synchronous targeting of WASL, integrin alpha V, and Additional Cytoskeletal Elements.
PLoS One 10(12):e0143993. doi: 10.1371/journal.pone.0143993.

 

Heinick A, Husser X, Himmler K, Kirchhefer U, Nunes F, Schulte JS, Seidl MD, Rolfes C, Dedman JR, Kaetzel MA, Gerke V, Schmitz W, Müller FU.
Annexin A4 is a novel direct regulator of adenylyl cyclase type 5.
FASEB J. 2015 Sep;29(9):3773-87. doi: 10.1096/fj.14-269837. Epub 2015 May 28.

 

Nammalwar RC, Heil A, Gerke V.
Ezrin interacts with the scaffold protein IQGAP1 and affects its cortical localization.
Biochim Biophys Acta. 2015 Sep;1853(9):2086-94. doi: 10.1016/j.bbamcr.2014.12.026. Epub 2014 Dec 30.
 


Tuncay H, Brinkmann BF, Steinbacher T, Schürmann A, Gerke V, Iden S, Ebnet K.
JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis.
Nat Commun. 2015 Aug 26;6:8128. doi: 10.1038/ncomms9128.

 

2014

 

Quiskamp N, Poeter M, Raabe CA, Hohenester UM, König S, Gerke V, Rescher U
The tumor suppressor annexin A10 is a novel component of nuclear paraspeckles.
Cell Mol Life Sci. 2014 Volume 71(2):311-29 JAN 2014

 

Poeter M, Brandherm I, Rossaint J, Rosso G, Shahin V, Skryabin BV, Zabock A, Gerke V, Rescher U
Annexin A8 controls leucocyte recruitment to activated endothelial cells via cells surface delivery of CD63.
Nature Commun 5: 3738. APR 2014

 

Musiol A, Gran S, Ehrhardt C, Ludwig S, Grewal T, Gerke V, Rescher U
Annexin A6-balanced late endosomal cholesterol controls Influenza A replication and propagation.
MBio 4(6): e00608-13. [doi: 10.1128/ mBio. 00608-13]

 

Wemmann DO, Schmitz J, Wehr MC, Krahn MP, Koschmal N, Gromni- tza, S, Schulze U, Weide T, Chekuri A, Skryabin BV, Gerke V, Paven- städt H, Duning K, Kremerskothen J.
Evolutionary and Molecular Facts Link the WWC Protein Family to Hip-po Signaling.
Mol Biol Evol. 2014 Apr 24. [Epub ahead of print]

 

Braunger, Julia A.; Brueckner, Bastian R.; Nehls, Stefan; Pietuch, Anna; Gerke, Volker; Mey, Ingo; Janshoff, Andreas; Steinem, Claudia
Phosphatidylinositol 4,5-Bisphosphate Alters the Number of Attachment Sites between Ezrin and Actin Filaments
A COLLOIDAL PROBE STUDY* JOURNAL OF BIOLOGICAL CHEMISTRY Volume: 289 Issue: 14 Pages: 9833-9843 Published: APR 4 2014

 

Druecker, Patrick; Gerke, Volker; Galla Hans-Joachim
Importance of phospholipid bilyer integrity in the analysis of protein- lipid-interactions
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Volume: 453 Issue:1, Pages: 143-147, Oct 10 2014

 

Druecker, Patrick; Pejic, Milena; Grill, David, Galla Hans-Joachim; Gerke, Volker;
Cooperative Binding of Annexin A2 to Cholesterol- and Phosphatidylinositol-4,5-Bisphosphate-Containing Bilayers
BIOPHYSICAL JOURNAL Volume: 107 Issue:9, Pages 2070-2081 Nov 4 2014

 

Druecker, Patrick; Grill, David, Gerke, Volker; Galla HJ
Formation and Characterization of Supported Lipid Bilayers Containing Phosphatidylinositol-4,5-bisphosphate and Cholesterol as Functional Surfaces
LANGMUIR Volume 30 Issue: 49, Pages 14877-14886, Dec 16 2014

 

Kumar, AV; Gassar, ES] ; Spillmann, D; Stock, C; Sen, YP; Zhang, T Van Kuppevelt, TH; Hulsewig, C; Kozlowski, EO; Pavao, MSG; Ibrahim, SA; Poeter, M; Rescher, U; Kiesel, L; Koduru, S; Yip, GW ; Gotte, M
HS3ST2 modulates breast cancer cell invasiveness via MAP kinase- and Tcf4 (Tcf7l2)-dependent regulation of protease and cadherin expression
INTERNATIONAL JOURNAL OF CANCER Volume: 135, Issue: 11, Pages: 2579-2592 DOI: 10.1002/ijc.28921, DEC 1 2014

 

2013

 

Chlystun M, Campanella M, Law AL, Duchen MR, Fatimathas L, Levine TP, Gerke V, Moss SE.
Regulation of mitochondrial morphogenesis by annexin A6.
PLoS One. Volume:8, Issue: 1 Article Number e53774 JAN 14 2013

 

Ebnet, Klaus
JAM-A and aPKC: A close pair during cell-cell contact maturation and tight junction formation in epithelial cells.
Tissue barriers Volume: 1 Issue: 1 Pages: e22993 Published: 2013-Jan-1

 

Kluger MS, Clark PR, Tellides G, Gerke V, Pober JS.
Claudin-5 controls intercellular barriers of human dermal microvascular but not human umbilical vein endothelial cells.
Arterioscler Thromb Vasc Biol. 2013 Volume:33, Issue: 3:, Pages: 489-500 March 2013

 

Tuncay, H.; Brinkmann, B. F.; Schuermann, A.; Ebnet K.
JAM-A controls planar spindle orientation in polarized epithelial cells by cortical phosphoinositide localization
MOLECULAR BIOLOGY OF THE CELL Volume: 24 Meeting Abstract: 1395 Published: 2013

 

Peddibhotla SS, Brinkmann BF, Kummer D, Tuncay H, Nakayama M, Adams RH, Gerke V, Ebnet K.
Tetraspanin CD9 links junctional adhesion molecule-A to αvβ3 integrin to mediate basic fibroblast growth factor-specific angiogenic signaling.
Mol Biol Cell. 2013 Volume: 24, Issue: 7, Pages :933-44 Apr 1 2013

 

Stadtmann, A; Germena, G; Block, H ; Boras, M Rossaint, J Sundd, P ; Lefort, C; Fisher, CI ; Buscher, K ; Gelschefarth, B; Urzainqui, A; Gerke, V; Ley, K; Zarbock, A
The PSGL-1-L-selectin signaling complex regulates neutrophil adhesion under flow

JOURNAL OF EXPERIMENTAL MEDICINE Volume: 201, Issue: 11, Pages 2171-2180 APR 2013

 

Duning K, Wennmann DO, Bokemeyer A, Reissner C, Wersching H, Thomas C, Buschert J, Guske K, Franzke V, Flöel A, Lohmann H, Knecht S, Brand SM, Pöter M, Rescher U, Missler M, Seelheim P, Pröpper C, Boeckers TM, Makuch L, Huganir R, Weide T, Brand E, Pavenstädt H, Kremerskothen J.
Common exonic missense variants in the C2 domain of the human KIBRA protein modify lipid binding and cognitive performance.
Transl Psychiatry. 2013 Jun 18;3:e272. doi: 10.1038/tp.2013.49.

 

Poeter M, Radke S, Koese M, Hessner F, Hegemann A, Musiol A, Gerke V, Grewal T, Rescher U.
Disruption of the annexin A1/S100A11 complex increases the migration and clonogenic growth by dysregulating epithelial growth factor (EGF) signaling.
Biochim Biophys Acta. Volume: 1833, Issue: 7, Pages:1700-11 JUL 2013

 

Druecker, P.; Pejic, M.; Gerke, V.; et al.
The Annexin A2 core domain is identified to induce membrane curvature
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS Volume: 42 Supplement: 1 Pages: S173-S173 Published: JUL 2013

 

Steinem, C.; Braunger, J.; Kramer, C.; Gerke, V.
Activation of ezrin: synergism of PIP2 interaction and phosphorylation
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LET TERS Volume: 42 Supplement: 1 Pages: S156-S156 Published: JUL 2013

 

Brinkmann, Benjamin F.; Ebnet, Klaus
The VE-Cadherin: PAR complex regulates lumen formation in endothelial cells
ANGIOGENESIS Volume: 17 Issue: 3 Pages: 730-731 Meeting Abstract: P-8 Published: JUL 2014

 

Druecker, Patrick; Pejic, Milena; Galla, Hans-Joachim; et al.
Lipid Segregation and Membrane Budding Induced by the Peripheral Membrane Binding Protein Annexin A2
JOURNAL OF BIOLOGICAL CHEMISTRY Volume: 288 Issue: 34 Pages: 24764-24776 Published: AUG 23 2013

 

Brandherm, Ines m; Disse, Jennifer; Zeuschner, Dagmar; Gerke, Volker
cAMP-induced secretion of endothelial von Willebrand factor is regulated by a phosphorylation/dephosphorylation switch in annexin A2
BLOOD Volume: 122 Issue: 6 Pages: 1042-1051 Published: AUG 8 2013

 

Druecker, Patrick; Pejic, Milena; Galla, Hans-Joachim; Gerke, V.
Lipid Segregation and Membrane Budding Induced by the Peripheral Membrane Binding Protein Annexin A2
JOURNAL OF BIOLOGICAL CHEMISTRY Volume: 288 Issue: 34 Pages: 24764-24776 Published: AUG 23 2013

 

Ghavampour S, Lange C, Bottino C, Gerke V.
Transcriptional profiling of human monocytes identifies the inhibitory rec ceptor CD300a as regulator of transendothelial migration.
PLoS One. Volume:8, Issue: 9, Article Number:e73981SEP 18 2013

 

Hooten WM, Townsend CO, Hays JT, Ebnet KL, Gauvin TR, Gehin JM, Laures HJ, Patten CA, Warner DO.
A cognitive behavioral smoking abstinence intervention for adults with chronic pain: a randomized controlled pilot trial.
Addict Behav. 2014 Mar;39(3):593-9. doi: 10.1016/j.addbeh.2013.11.010. Epub 2013 Nov 21.

 

Musiol A, Gran S, Ehrhardt C, Ludwig S, Grewal T, Gerke V, Rescher U.
Annexin A6-balanced late endosomal cholesterol controls influenza a replication and propagation.
MBio. 2013 Nov 5;4(6), Article number: e00608-13, NOV-DEC 2013

 

 

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2012

Yuan S, Ghoshdastider U, Trzaskowski B, Latek D, Debinski A, Pulawski W, Wu R, Gerke V, Filipek S.

The role of water in activation mechanism of human N-formyl peptide receptor 1 (FPR1) based on molecular dynamics simulations.

PLoS One. 2012;7(11):e47114. doi: 10.1371/journal.pone.0047114. Epub 2012 Nov 26.

 

Nazmi AR, Ozorowski G, Pejic M, Whitelegge JP, Gerke V, Luecke H.

N-terminal acetylation of annexin A2 is required for S100A10 binding.

Biol Chem. 2012 Oct;393(10):1141-50. doi: 10.1515/hsz-2012-0179.

 

Tcatchoff L, Andersson S, Utskarpen A, Klokk TI, Skånland SS, Pust S, Gerke V, Sandvig K.

Annexin A1 and A2: roles in retrograde trafficking of Shiga toxin.

PLoS One. 2012;7(7):e40429. doi: 10.1371/journal.pone.0040429. Epub 2012 Jul 6.

 

Iden S, Misselwitz S, Peddibhotla SS, Tuncay H, Rehder D, Gerke V, Robenek H, Suzuki A, Ebnet K.

aPKC phosphorylates JAM-A at Ser285 to promote cell contact maturation and tight junction formation.

J Cell Biol. 2012 Mar 5;196(5):623-39. doi: 10.1083/jcb.201104143. Epub 2012 Feb 27.

 

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2011

Gerke, V

Von Willebrand factor folds into a bouquet.

EMBO J. 2011 Oct 5;30(19):3880-1. doi: 10.1038/emboj.2011.321.

 

Rojo Pulido I, Nightingale TD, Darchen F, Seabra MC, Cutler DF, Gerke V.

Myosin Va Acts in Concert with Rab27a and MyRIP to Regulate Acute Von-Willebrand Factor Release from Endothelial Cells.

Traffic. 2011 Oct;12(10):1371-1382. doi: 10.1111/j.1600-0854.2011.01248.x. Epub 2011 Aug 5.

 

Pulido IR, Jahn R, Gerke V

VAMP3 is associated with endothelial weibel-palade bodies and participates in their Ca(2+)-dependent exocytosis.

Biochim Biophys Acta. 2011;1813(5): 1038-44

 

Bosk S, Braunger JA, Gerke V, Steinem C

Activation of F-actin binding capacity of ezrin: synergism of PIP2 interaction and phosphorylation.

Biophys J. 2011;100(7): 1708-17

 

Heil A, Nazmi AR, Koltzscher M. Poeter M., Austermann J, Assard N, Baudier J, Kaubuchi K, Gerke V

S100P is a novel interaction partner and regulator of IQGAP1.

J Biol Chem. 2011;286(9): 7227-38

 

Gauthier-Kemper A, Weissmann C, Golovyashkina N, Sebö-Lemke Z, Drewes G, Gerke V, Heinisch JJ, Brandt R.
The frontotemporal dementia mutation R406W blocks tau's interaction with the membrane in an annexin A2-dependent manner.
J Cell Biol. 2011 Feb 21;192(4):647-61. Pubmed

Pupjalis D, Goetsch J, Kottas DJ, Gerke V, Rescher U.
Annexin A1 released from apoptotic cells acts through formyl peptide receptors to dampen inflammatory monocyte activation via JAK/STAT/SOCS signalling.
EMBO Mol Med. 2011 Feb;3(2):102-14. Pubmed


Patel DM, Ahmad SF, Weiss DG, Gerke V, Kuznetsov SA.
Annexin A1 is a new functional linker between actin filaments and phagosomes during phagocytosis.
J Cell Sci. 2011 Feb 15;124(Pt 4):578-88. Pubmed

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2010

Heil A, Nazmi AR, Koltzscher M, Poeter M, Austermann J, Assard N, Baudier J, Kaibuchi K, Gerke V.
S100P is a novel interaction partner and regulator of IQGAP1.
J Biol Chem. 2010 Dec 22. Pubmed

Pulido IR, Jahn R, Gerke V.
VAMP3 is associated with endothelial Weibel-Palade bodies and participates in their Ca(2+)-dependent exocytosis.
Biochim Biophys Acta. 2010 Nov 20. Pubmed

Markoff A, Gerdes S, Feldner S, Bogdanova N, Gerke V, Grandone E.
Reduced allele specific annexin A5 mRNA levels in placentas carrying the M2/ANXA5 allele.
Placenta. 2010 Oct;31(10):937-40. Pubmed

Backes P, Quinkert D, Reiss S, Binder M, Zayas M, Rescher U, Gerke V, Bartenschlager R, Lohmann V.
Role of annexin A2 in the production of infectious hepatitis C virus particles.
J Virol. 2010 Jun;84(11):5775-89. Pubmed

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2009

Choudhary C, Olsen JV, Brandts C, Cox J, Reddy PN, Böhmer FD, Gerke V, Schmidt-Arras DE, Berdel WE, Müller-Tidow C, Mann M, Serve H.
Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes.
Mol Cell. 2009 Oct 23;36(2):326-39.Pubmed

Markoff A, Gerke V, Bogdanova N.
Combined homology modelling and evolutionary significance evaluation of missense mutations in blood clotting factor VIII to highlight aspects of structure and function.
Haemophilia. 2009 Jul;15(4):932-41. Epub 2009 Apr 7.Pubmed

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2008

Bulk E, Sargin B, Krug U, Hascher A, Jun Y, Knop M, Kerkhoff C, Gerke V, Liersch R, Mesters RM, Hotfilder M, Marra A, Koschmieder S, Dugas M, Berdel WE, Serve H, Müller-Tidow C.
S100A2 Induces Metastasis in Non-Small Cell Lung Cancer.
Clin Cancer Res. 2009 Jan 1;15(1):22-29.Pubmed

Austermann J, Nazmi AR, Heil A, Fritz G, Kolinski M, Filipek S, Gerke V.
Generation and characterization of a novel, permanently active S100P mutant.
Biochim Biophys Acta. 2008 Dec 8. [Epub ahead of print] Pubmed

Disse J, Vitale N, Bader MF, Gerke V.
Phospholipase D1 is specifically required for regulated secretion of von-Willebrand factor from endothelial cells.
Blood. 2008 Oct 22. [Epub ahead of print] Pubmed

Goebeler V, Poeter M, Zeuschner D, Gerke V, Rescher U.
Annexin A8 Regulates Late Endosome Organization and Function.
Mol Biol Cell. 2008 Dec;19(12):5267-78. Epub 2008 Oct 15.Pubmed

Austermann J, Nazmi AR, Müller-Tidow C, Gerke V.
Characterization of the Ca2+-regulated Ezrin-S100P Interaction and Its Role in Tumor Cell Migration.
J Biol Chem. 2008 Oct 24;283(43):29331-40. Epub 2008 Aug 25. Pubmed

Rescher U, Ludwig C, Konietzko V, Kharitonenkov A, Gerke V.
Tyrosine phosphorylation of annexin A2 regulates Rho-mediated actin rearrangement and cell adhesion.
J Cell Sci. 2008 Jul 1;121(Pt 13):2177-85.Pubmed

Ebnet K, Iden S, Gerke V, Suzuki A.
Regulation of epithelial and endothelial junctions by PAR proteins
Front Biosci. 2008 May 1;13:6520-36 Pubmed

Borthwick LA, Riemen C, Goddard C, Colledge WH, Mehta A, Gerke V, Muimo R.
Defective formation of PKA/CnA-dependent annexin 2-S100A10/CFTR complex in DeltaF508 cystic fibrosis cells.
Cell Signal. 2008 Jun;20(6):1073-83. Epub 2008 Feb 5. Pubmed

Bulk E, Hascher A, Liersch R, Mesters RM, Diederichs S, Sargin B, Gerke V, Hotfilder M, Vormoor J, Berdel WE, Serve H, Müller-Tidow C.
Adjuvant therapy with small hairpin RNA interference prevents non-small cell lung cancer metastasis development in mice.
Cancer Res. 2008 Mar 15;68(6):1896-904. Pubmed

Janke M, Herrig A, Austermann J, Gerke V, Steinem C, Janshoff, A
Actin Binding of Ezrin is Activated by Specific Recognition of PIP2-Functionalized Lipid Bilayers
Biochemistry. 2008 Feb 27; [Epub ahead of print] Pubmed

Borthwick LA, Neal A, Hobson L, Gerke V, Robson L, Muimo R.
The annexin 2-S100A10 complex and its association with TRPV6 is regulated by cAMP/PKA/CnA in airway and gut epithelia.
Cell Calcium. 2008 Jan 8; [Epub ahead of print] Pubmed

van de Graaf SF, Rescher U, Hoenderop JG, Verkaart S, Bindels RJ, Gerke V.
TRPV5 is internalized via clathrin-dependent endocytosis to enter a Ca2+-controlled recycling pathway.
J Biol Chem. 2008 Feb 15;283(7):4077-86. Epub 2007 Dec 12 Pubmed

 

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2007

Lange C, Starrett D, Goetsch J, Gerke V, Rescher U.
Transcriptional profiling of human monocytes reveals complex changes in the expression pattern of inflammation-related genes in response to the annexin A1 derived peptide Ac1-25
J Leukoc Biol. 2007 Dec;82(6):1592-604. Epub 2007 Sep 12 Pubmed

Shpacovitch VM, Seeliger S, Huber-Lang M, Balkow S, Feld M, Hollenberg MD, Sarma VJ, Ward PA, Strey A, Gerke V, Sommerhoff CP, Vergnolle N, Steinhoff M.
Agonists of proteinase-activated receptor-2 affect transendothelial migration and apoptosis of human neutrophils.
Exp Dermatol. 2007 Oct;16(10):799-806. Pubmed

Rescher U, Gerke V.
S100A10/p11: family, friends and functions.
Pflugers Arch. 2007 Jul 19; [Epub ahead of print]Pubmed

Borthwick LA, McGaw J, Conner G, Taylor CJ, Gerke V, Mehta A, Robson L, Muimo R.
The Formation of the cAMP/PKA-dependent Annexin 2-S100A10 Complex with CFTR Regulates CFTR Channel Function.
Mol Biol Cell. 2007 Jun 20; [Epub ahead of print] Pubmed

Markoff A, Bogdanova N, Knop M, Ruffer C, Kenis H, Lux P, Reutelingsperger C, Todorov V, Dworniczak B, Horst J, Gerke V.
Annexin A5 Interacts with Polycystin-1 and Interferes with the Polycystin-1 Stimulated Recruitment of E-cadherin into Adherens Junctions.
J Mol Biol. 2007 Jun 15;369(4):954-66. Epub 2007 Mar 31. Pubmed

Bogdanova N, Horst J, Chlystun M, Croucher PJ, Nebel A, Bohring A, Todorova A, Schreiber S, Gerke V, Krawczak M, Markoff A.
A common haplotype of the annexin A5 (ANXA5) gene promoter is associated with recurrent pregnancy loss.
Hum Mol Genet. 2007 Mar 1;16(5):573-8. Epub 2007 Mar 5. Pubmed

Martin-Belmonte F, Gassama A, Datta A, Yu W, Rescher U, Gerke V, Mostov K.
PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42.
Cell. 2007 Jan 26;128(2):383-97. Pubmed

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2006

Herrig A, Janke M, Austermann J, Gerke V, Janshoff A, Steinem C.
Cooperative adsorption of ezrin on PIP2-containing membranes.
Biochemistry. 2006 Oct 31;45(43):13025-34. Pubmed

 

Foulkes T, Nassar MA, Lane T, Matthews EA, Baker MD, Gerke V, Okuse K, Dickenson AH, Wood JN.
Deletion of annexin 2 light chain p11 in nociceptors causes deficits in somatosensory coding and pain behavior.
J Neurosci. 2006 Oct 11;26(41):10499-507. Pubmed

 

Rescher U, Goebeler V, Wilbers A, Gerke V.
Proteolytic cleavage of annexin 1 by human leukocyte elastase.
Biochim Biophys Acta. 2006 Nov;1763(11):1320-4. Epub 2006 Sep 1. Pubmed

 

McNeil AK, Rescher U, Gerke V, McNeil PL.
Requirement for annexin A1 in plasma membrane repair.
J Biol Chem. 2006 Nov 17;281(46):35202-7. Epub 2006 Sep 19. Pubmed

 

De Seranno S, Benaud C, Assard N, Khediri S, Gerke V, Baudier J, Delphin C.
Identification of an AHNAK binding motif specific for the Annexin2/S100A10 tetramer.
J Biol Chem. 2006 Nov 17;281(46):35030-8. Epub 2006 Sep 19. Pubmed

 

Tatenhorst L, Rescher U, Gerke V, Paulus W.
Knockdown of annexin 2 decreases migration of human glioma cells in vitro.
Neuropathol Appl Neurobiol. 2006 Jun;32(3):271-7. Pubmed

 

Goebeler V, Ruhe D, Gerke V, Rescher U.
Annexin A8 displays unique phospholipid and F-actin binding properties.
FEBS Lett. 2006 May 1;580(10):2430-4. Epub 2006 Apr 7. Pubmed

 

Tickenbrock L, Schwable J, Strey A, Sargin B, Hehn S, Baas M, Choudhary C, Gerke V, Berdel WE, Muller-Tidow C, Serve H.
Wnt signaling regulates transendothelial migration of monocytes.
J Leukoc Biol. 2006 Jun;79(6):1306-13. Epub 2006 Mar 24. Pubmed

 

Kastl K, Menke M, Luthgens E, Faiss S, Gerke V, Janshoff A, Steinem C.
Partially reversible adsorption of annexin A1 on POPC/POPS bilayers investigated by QCM measurements, SFM, and DMC simulations.
Chembiochem. 2006 Jan;7(1):106-15. Pubmed

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2005

Menke M, Gerke V, Steinem C.
Phosphatidylserine membrane domain clustering induced by annexin A2/S100A10 heterotetramer.
Biochemistry. 2005 Nov 22;44(46):15296-303. Pubmed

 

Markoff A, Gerke V.
Expression and functions of annexins in the kidney.
Am J Physiol Renal Physiol. 2005 Nov;289(5):F949-56. Review. Pubmed

 

Hackmann K, Markoff A, Qian F, Bogdanova N, Germino GG, Pennekamp P, Dworniczak B, Horst J, Gerke V.
A splice form of polycystin-2, lacking exon 7, does not interact with polycystin-1.
Hum Mol Genet. 2005 Nov 1;14(21):3249-62. Epub 2005 Sep 28. Pubmed

 

Gerke V, Creutz CE, Moss SE.
Annexins: linking Ca2+ signalling to membrane dynamics.
Nat Rev Mol Cell Biol. 2005 Jun;6(6):449-61. Review. Pubmed

 

Chasserot-Golaz S, Vitale N, Umbrecht-Jenck E, Knight D, Gerke V, Bader MF.
Annexin 2 promotes the formation of lipid microdomains required for calcium-regulated exocytosis of dense-core vesicles.
Mol Biol Cell. 2005 Mar;16(3):1108-19. Epub 2005 Jan 5. Pubmed

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2004

Viemann D, Strey A, Janning A, Jurk K, Klimmek K, Vogl T, Hirono K, Ichida F, Foell D, Kehrel B, Gerke V, Sorg C, Roth J.
Myeloid-related proteins 8 and 14 induce a specific inflammatory response in human microvascular endothelial cells.
Blood. 2005 Apr 1;105(7):2955-62. Epub 2004 Dec 14. Pubmed

 

Chlystun M, Markoff A, Gerke V.
Structural and functional characterisation of the mouse annexin A9 promoter.
Biochim Biophys Acta. 2004 Dec 6;1742(1-3):141-9. Pubmed

 

Radke S, Austermann J, Russo-Marie F, Gerke V, Rescher U.
Specific association of annexin 1 with plasma membrane-resident and internalized EGF receptors mediated through the protein core domain.
FEBS Lett. 2004 Dec 3;578(1-2):95-8. Pubmed

 

Vogl T, Ludwig S, Goebeler M, Strey A, Thorey IS, Reichelt R, Foell D, Gerke V, Manitz MP, Nacken W, Werner S, Sorg C, Roth J.
MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes.
Blood. 2004 Dec 15;104(13):4260-8. Epub 2004 Aug 26. Pubmed

 

Imanishi Y, Gerke V, Palczewski K.
Retinosomes: new insights into intracellular managing of hydrophobic substances in lipid bodies.
J Cell Biol. 2004 Aug 16;166(4):447-53. Review. Pubmed

 

Diederichs S, Bulk E, Steffen B, Ji P, Tickenbrock L, Lang K, Zanker KS, Metzger R, Schneider PM, Gerke V, Thomas M, Berdel WE, Serve H, Muller-Tidow C.
S100 family members and trypsinogens are predictors of distant metastasis and survival in early-stage non-small cell lung cancer.
Cancer Res. 2004 Aug 15;64(16):5564-9. Pubmed

 

Hayes MJ, Rescher U, Gerke V, Moss SE.
Annexin-actin interactions.
Traffic. 2004 Aug;5(8):571-6. Review. Pubmed

 

Ruffer C, Gerke V.
The C-terminal cytoplasmic tail of claudins 1 and 5 but not its PDZ-binding motif is required for apical localization at epithelial and endothelial tight junctions.
Eur J Cell Biol. 2004 May;83(4):135-44. Pubmed

 

Knop M, Aareskjold E, Bode G, Gerke V.
Rab3D and annexin A2 play a role in regulated secretion of vWF, but not tPA, from endothelial cells.
EMBO J. 2004 Aug 4;23(15):2982-92. Epub 2004 Jul 15. Pubmed

 

Menke M, Ross M, Gerke V, Steinem C.
The molecular arrangement of membrane-bound annexin A2-S100A10 tetramer as revealed by scanning force microscopy.
Chembiochem. 2004 Jul 5;5(7):1003-6. No abstract available. Pubmed

 

Rescher U, Ruhe D, Ludwig C, Zobiack N, Gerke V.
Annexin 2 is a phosphatidylinositol (4,5)-bisphosphate binding protein recruited to actin assembly sites at cellular membranes.
J Cell Sci. 2004 Jul 15;117(Pt 16):3473-80. Epub 2004 Jun 29. Pubmed

 

Ernst S, Zobiack N, Boecker K, Gerke V, Rescher U.
Agonist-induced trafficking of the low-affinity formyl peptide receptor FPRL1. Cell Mol Life Sci. 2004 Jul;61(13):1684-92. Pubmed

 

Ernst S, Lange C, Wilbers A, Goebeler V, Gerke V, Rescher U.
An annexin 1 N-terminal peptide activates leukocytes by triggering different members of the formyl peptide receptor family.
J Immunol. 2004 Jun 15;172(12):7669-76. Pubmed

 

Rescher U, Gerke V.
Annexins--unique membrane binding proteins with diverse functions.
J Cell Sci. 2004 Jun 1;117(Pt 13):2631-9. Review. Pubmed

 

Shpacovitch VM, Varga G, Strey A, Gunzer M, Mooren F, Buddenkotte J, Vergnolle N, Sommerhoff CP, Grabbe S, Gerke V, Homey B, Hollenberg M, Luger TA, Steinhoff M.
Agonists of proteinase-activated receptor-2 modulate human neutrophil cytokine secretion, expression of cell adhesion molecules, and migration within 3-D collagen lattices.
J Leukoc Biol. 2004 Aug;76(2):388-98. Epub 2004 May 20. Pubmed

 

Ruffer C, Strey A, Janning A, Kim KS, Gerke V.
Cell-cell junctions of dermal microvascular endothelial cells contain tight and adherens junction proteins in spatial proximity.
Biochemistry. 2004 May 11;43(18):5360-9. Pubmed

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2003

Monastyrskaya K, Babiychuk EB, Schittny JC, Rescher U, Gerke V, Mannherz HG, Draeger A.
The expression levels of three raft-associated molecules in cultivated vascular cells are dependent on culture conditions.
Cell Mol Life Sci. 2003 Dec;60(12):2702-9. Pubmed

 

Jacob R, Heine M, Eikemeyer J, Frerker N, Zimmer KP, Rescher U, Gerke V, Naim HY.
Annexin II is required for apical transport in polarized epithelial cells. J Biol Chem. 2004 Jan 30;279(5):3680-4. Epub 2003 Dec 11. Pubmed

 

Zobiack N, Rescher U, Ludwig C, Zeuschner D, Gerke V.
The annexin 2/S100A10 complex controls the distribution of transferrin receptor-containing recycling endosomes.
Mol Biol Cell. 2003 Dec;14(12):4896-908. Epub 2003 Sep 17. Pubmed

 

Goebeler V, Ruhe D, Gerke V, Rescher U.
Atypical properties displayed by annexin A9, a novel member of the annexin family of Ca(2+) and lipid binding proteins.
FEBS Lett. 2003 Jul 10;546(2-3):359-64. Pubmed

 

Koltzscher M, Neumann C, Konig S, Gerke V.
Ca2+-dependent binding and activation of dormant ezrin by dimeric S100P. Mol Biol Cell. 2003 Jun;14(6):2372-84.
Pubmed

 

van de Graaf SF, Hoenderop JG, Gkika D, Lamers D, Prenen J, Rescher U, Gerke V, Staub O, Nilius B, Bindels RJ.
Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex.
EMBO J. 2003 Apr 1;22(7):1478-87. Pubmed

 

Ross M, Gerke V, Steinem C.
Membrane composition affects the reversibility of annexin A2t binding to solid supported membranes: a QCM study.
Biochemistry. 2003 Mar 18;42(10):3131-41. Pubmed

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2002

Knop M, Gerke V.
Ca2+ -regulated secretion of tissue-type plasminogen activator and von Willebrand factor in human endothelial cells.
Biochim Biophys Acta. 2002 Nov 4;1600(1-2):162-7. Pubmed PMID: 12445472 [PubMed - indexed for MEDLINE]

 

Kastl K, Ross M, Gerke V, Steinem C.
Kinetics and thermodynamics of annexin A1 binding to solid-supported membranes: a QCM study.
Biochemistry. 2002 Aug 6;41(31):10087-94. Pubmed

 

Rescher U, Danielczyk A, Markoff A, Gerke V.
Functional activation of the formyl peptide receptor by a new endogenous ligand in human lung A549 cells.
J Immunol. 2002 Aug 1;169(3):1500-4. Pubmed

 

Strey A, Janning A, Barth H, Gerke V.
Endothelial Rho signaling is required for monocyte transendothelial migration.
FEBS Lett. 2002 Apr 24;517(1-3):261-6. Pubmed

 

Gerke V, Moss SE.
Annexins: from structure to function.
Physiol Rev. 2002 Apr;82(2):331-71. Review. Pubmed

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2001

Janshoff A, Ross M, Gerke V, Steinem C.
Visualization of annexin I binding to calcium-induced phosphatidylserine domains.
Chembiochem. 2001 Aug 3;2(7-8):587-90. No abstract available. Pubmed

 

Zobiack N, Rescher U, Laarmann S, Michgehl S, Schmidt MA, Gerke V.
Cell-surface attachment of pedestal-forming enteropathogenic E. coli induces a clustering of raft components and a recruitment of annexin 2.
J Cell Sci. 2002 Jan 1;115(Pt 1):91-8. Pubmed

 

Zeuschner D, Stoorvogel W, Gerke V.
Association of annexin 2 with recycling endosomes requires either calcium- or cholesterol-stabilized membrane domains.
Eur J Cell Biol. 2001 Aug;80(8):499-507. Pubmed

 

Gerke V.
Annexins And Membrane Organisation In The Endocytic Pathway.
Cell Mol Biol Lett. 2001;6(2):204. No abstract available. Pubmed

 

Merrifield CJ, Rescher U, Almers W, Proust J, Gerke V, Sechi AS, Moss SE.
Annexin 2 has an essential role in actin-based macropinocytic rocketing.
Curr Biol. 2001 Jul 24;11(14):1136-41. Pubmed

 

Zobiack N, Gerke V, Rescher U.
Complex formation and submembranous localization of annexin 2 and S100A10 in live HepG2 cells.
FEBS Lett. 2001 Jul 6;500(3):137-40. Pubmed

 

Bogdanova N, Markoff A, Gerke V, McCluskey M, Horst J, Dworniczak B.
Homologues to the first gene for autosomal dominant polycystic kidney disease
are pseudogenes. Genomics. 2001 Jun 15;74(3):333-41. Pubmed

 

Kielbassa-Schnepp K, Strey A, Janning A, Missiaen L, Nilius B, Gerke V.
Endothelial intracellular Ca2+ release following monocyte adhesion is required
for the transendothelial migration of monocytes. Cell Calcium. 2001 Jul;30(1):29-40. Pubmed

 

Rosengarth A, Rosgen J, Hinz HJ, Gerke V.
Folding energetics of ligand binding proteins II. Cooperative binding of Ca2+ to annexin I.
J Mol Biol. 2001 Mar 2;306(4):825-35. Pubmed

 

Rosengarth A, Gerke V, Luecke H.
X-ray structure of full-length annexin 1 and implications for membrane aggregation.
J Mol Biol. 2001 Feb 23;306(3):489-98. Pubmed

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2000

Konig J, Gerke V.
Modes of annexin-membrane interactions analyzed by employing chimeric annexin proteins.
Biochim Biophys Acta. 2000 Dec 20;1498(2-3):174-80. Pubmed

 

Russo-Marie F, Donato R, Gerke V V, Haiech J, Heizmann CW, Pochet R.
Preface. . 2000 Dec 20;1498(2-3):81. No abstract available. Pubmed

 

Lewit-Bentley A, Rety S, Sopkova-de Oliveira Santos J, Gerke V.
S100-annexin complexes: some insights from structural studies.
Cell Biol Int. 2000;24(11):799-802. Pubmed

 

Rescher U, Zobiack N, Gerke V.
Intact Ca(2+)-binding sites are required for targeting of annexin 1 to endosomal membranes in living HeLa cells.
J Cell Sci. 2000 Nov;113 ( Pt 22):3931-8. Pubmed

 

Muimo R, Hornickova Z, Riemen CE, Gerke V, Matthews H, Mehta A.
Histidine phosphorylation of annexin I in airway epithelia.
J Biol Chem. 2000 Nov 24;275(47):36632-6. Pubmed

 

Koltzscher M, Gerke V.
Identification of hydrophobic amino acid residues involved in the formation of S100P homodimers in vivo.
Biochemistry. 2000 Aug 8;39(31):9533-9. Pubmed

 

Lang F, Klingel K, Wagner CA, Stegen C, Warntges S, Friedrich B, Lanzendorfer M, Melzig J, Moschen I, Steuer S, Waldegger S, Sauter M, Paulmichl M, Gerke V, Risler T, Gamba G, Capasso G, Kandolf R, Hebert SC, Massry SG, Broer S.
Deranged transcriptional regulation of cell-volume-sensitive kinase hSGK in diabetic nephropathy.
Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):8157-62. Pubmed

 

Walther A, Riehemann K, Gerke V.
A novel ligand of the formyl peptide receptor: annexin I regulates neutrophil extravasation by interacting with the FPR.
Mol Cell. 2000 May;5(5):831-40. Pubmed

 

Rety S, Osterloh D, Arie JP, Tabaries S, Seeman J, Russo-Marie F, Gerke V, Lewit-Bentley A.
Structural basis of the Ca(2+)-dependent association between S100C (S100A11) and its target, the N-terminal part of annexin I.
Structure. 2000 Feb 15;8(2):175-84. Pubmed

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