A02: Publications


  1. Sakalem ME, Seidenbecher T, Zhang M, Saffari R, Kravchenko M, Wördemann S, Diederich K, Schwamborn JC, Zhang W, Ambrée O (2017)
    Environmental enrichment and physical exercise revert behavioral and electrophysiological impairments caused by reduced adult neurogenesis.
    Hippocampus 27(1):36-51. doi: 10.1002/hipo.22669.
  2. Lange MD, Daldrup T, Remmers F, Szkudlarek HJ, Lesting J, Guggenhuber S, Ruehle S, Jüngling K, Seidenbecher T, Lutz B, Pape HC (2017)
    Cannabinoid CB1 receptors in distinct circuits of the extended amygdala determine fear responsiveness to unpredictable threat.
    Mol Psychiatry 22(10):1422-1430. doi: 10.1038/mp.2016.156.


  1. Seidenbecher T, Remmes J, Daldrup T, Lesting J, Pape H-C (2016)
    Distinct state anxiety after predictable and unpredictable fear training in mice. Behavioural Brain Research 304: 20-23.
  2. Daldrup T, Lesting J, Meuth P, Seidenbecher T, Pape H-C (2016)
    Neuronal correlates of sustained fear in the anterolateral part of the bed nucleus of stria terminalis. Neurobiology of Learning  and Memory 131:137-146.
  3. Remmes J, Bodden C, Richter SH, Lesting J, Sachser N, Pape HC, Seidenbecher T (2016)
    Impact of Life History on Fear Memory and Extinction.
    Front Behav Neurosci 4;10:185. eCollection 2016.


  1. Daldrup T, Remmes J, Lesting J, Gaburro S, Fendt M, Meuth P, Kloke V, Pape H-C and Seidenbecher T, (2015)
    Expression of freezing and fear-potentiated startle during sustained fear in mice. Genes, Brain Behav. 14(3):281-291.


  1. Kumsta R, Chen FS, Pape H-C, Heinrichs M (2013)
    Neuropeptide S receptor gene is associated with cortisol responses to social stress in humans. Biol. Psychology; Mar 4;93(2):304-307. doi: 10.1016/j.biopsycho.2013.02.018. [Epub ahead of print]
  2. Lesting J, Daldrup T, Narayanan V, Himpe C, Seidenbecher T, Pape H-C (2013)
    Directional theta coherence in prefrontal cortical to amygdalo-hippocampal pathways signals fear extinction. PLoS One. 2013 Oct 24;8(10):e77707.
  3. Meuth P, Gaburro S, Lesting J, Legler A, Herty M, Budde T, Meuth SG, Seidenbecher T, Lutz B, Pape H-C (2013)
    Standardizing the analysis of conditioned fear in rodents: a multidimensional software approach. Genes Brain Behav. 12(5):583-92.


  1. Seidenbecher T, Lesting J (2012)
    Amygdala-hippocampal Theta Synchronyin Learning, Memory and Disease
    In: Insights Into the Amygdala: Structure, Functions and Implications for Disorders (Neuroanatomy Research at the Leading Edge), Nova Press 2012; Ed.: Deniz-Yilmazer-Hanke
  2. Chauveau F, Lange MD, Jüngling K, Lesting J, Seidenbecher T, Pape HC (2012)
    Prevention of stress-impaired fear extinction through neuropeptide S action in the lateral amygdala. Neuropsychopharmacol. (7):1588-99


  1. Lesting J, Narayanan RT, Kluge C, Sangha S, Seidenbecher T, Pape HC (2011)
    Patterns of Coupled Theta Activity in Amygdala-Hippocampal-Prefrontal Cortical Circuits during Fear Extinction.
    PLoS ONE 6(6): e21714. doi:10.1371/journal.pone.0021714 
  2. Narayanan V, Heiming RS, Jansen F, Lesting J, Sachser N,  Pape HC, Seidenbecher T (2011)
    Social Defeat: Impact on Fear Extinction and Amygdala-Prefrontal Cortical Theta Synchrony in 5-HTT Deficient Mice
    PLoS ONE: 6(7): e22600. doi:10.1371/journal.pone.0022600


  1. Pape HC, Jüngling K, Seidenbecher T, Lesting J, Reinscheid RK (2010)
    Neuropeptide S: a transmitter system in the brain regulating fear and anxiety.
    Neuropharmacology 58(1): 29-34. Review.
  2. Kamprath K, Romo-Parra H, Häring M, Gaburro S, Döngi M,Lutz B, Pape HC (2010) Short-term adaption of conditioned fear responses through endocannabinoid signaling in the central amygdala. Neuropsychopharmacology 36(3):652-63.
  3. Lesting J, Geiger M, Narayanan RT, Pape HC, Seidenbecher T (2010)
    Impaired extinction of fear and maintained amygdala-hippocampal theta synchrony in a mouse model of temporal lobe epilepsy. Epilepsia 52(2):337-46


  1. Sangha S, Narayanan RT, Bergado-Acosta JR, Stork O, Seidenbecher T, Pape HC (2009)
    Deficiency of the 65 kDa isoform of glutamic acid decarboxylase impairs extinction of cued but not contextual fear memory.
    J Neurosci. 16; 29(50):15713-20.
  2. Moran RJ, Stephan KE, Seidenbecher T, Pape HC, Dolan RJ, Friston KJ (2009)
    Dynamic causal models of steady-state responses. Neuroimage 44: 796-811.


  1. Jüngling K, Seidenbecher T, Sosulina L, Lesting J, Sangha S, Clark SD, Okamura N, Duangdao DM, Xu YL, Reinscheid RK, Pape HC (2008)
    Neuropeptide S-mediated control of fear expression and extinction: role of intercalated GABAergic neurons in the amygdala.
    Neuron  31;59(2):298-310.