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  1. D. Verma, R. Tasan, G. Sperk & H.-C. Pape,
    Neuropeptide Y2 receptors in anteroventral BNST control remote fear memory depending on extinction training. Neurobiol Learn Mem 149, 144-153 (2018).
  2. A.L. Walter, J.C. Bartsch, M. Datunashvili, P. Blaesse, M.D. Lange, H.-C. Pape,
    Physiological profile of neuropeptide Y-expressing neurons in bed nucleus of stria terminalis in mice: state of high excitability. Front. Cell. Neurosci. (in press).
  3. M.D. Lange, T. Daldrup, F. Remmers, H.J. Szkudlarek, J. Lesting, S. Guggenhuber, S. Ruehle, K. Jüngling, T. Seidenbecher, B. Lutz, H.-C. Pape,
    Cannabinoid CB1 receptors in distinct circuits of the extended amygdala determine fear responsiveness to unpredictable threat. Mol Psychiatry 22,1422-1430 (2017).   
  4. J. Waider, S. Popp, M.D. Lange, R. Kern, J. Kolter, J. Kobler, N.C. Donner, K.R. Lowe, J.H. Malzbender, C.J. Brazell, M.R. Arnold, A. Schmitt, C.A. Lowry, H.-C. Pape, K.P. Lesch,
    Genetically driven brain serotonin deficiency facilitates panic-like escape behaviour in mice. Transl Psychiatry 7:e1246 (2017).
  5. F. Remmers, M.D. Lange, M. Hamann, S. Ruehle, H.-C. Pape, B. Lutz,
    Conditional genetic rescue of the CB1 receptor on forebrain GABAergic neurons to assess sufficiency for endocannabinoid-mediated functions. Brain Struct Funct 222, 3431-3452 (2017).
  6. T. Seidenbecher, J. Remmes, T. Daldrup, J. Lesting & H.-C. Pape,
    Distinct state anxiety after predictable and unpredictable fear training in mice. Behav.Brain Res. 304, 20-23 (2016).
  7. K. Jüngling, P. Blaesse, L. Goedecke & H.-C. Pape,
    Dynorphin-dependent reduction of excitability and attenuation of inhibitory afferents of NPS neurons in the pericoerulear region of mice. Front. Cell. Neurosci 10, 61 (2016).
  8. D. Kohmann, A. Lüttjohann, T. Seidenbecher, P. Coulon & H.-C. Pape,
    Short term depression of gap junctional coupling in reticular thalamic neurons of absence epileptic rats. J. Physiol. (Lond.) 2016 Mar 4. doi: 10.1113/JP271811. [Epub ahead of print].
  9. C. Neyer, D. Herr, D. Kohmann, T. Budde, H.-C. Pape & P. Coulon,
    mGluR-mediated calcium signalling in the thalamic reticular nucleus. Cell Calcium 59, 312-323 (2016).
  10. T. Daldrup, J. Lesting, P. Meuth, T. Seidenbecher & H.-C. Pape,
    Neuronal correlates of sustained fear in the anterolateral part of the bed nucleus of stria terminalis. Neurobiology Learning Memory 2016 Mar 30;131:137-146. doi: 10.1016/j.nlm.2016.03.020. [Epub ahead of print].
  11. M. Leist, M. Datunashvilli, T. Kanyshkova, M. Zobeiri, A. Aissaoui, M. Cerina, M.N. Romanelli, H.-C. Pape & T. Budde,
    Two types of interneurons in the mouse lateral geniculate nucleus are characterized by different h-current density. Science Reports 6:24904 (2016).
  12. M.D. Lange, T. Daldrup, F. Remmers, H. J. Szkudlarek, J. Lesting, S. Guggenhuber, S. Ruehle, K. Jüngling, T. Seidenbecher, B. Lutz & H.- C. Pape,
    Cannabinoid CB1 receptors in distinct circuits of the extended amygdala determine fear responsiveness to unpredictable threat. Mol Psychiatry (in press).

  13. K. Jüngling, M. Lange, H. Szkudlarek, J. Lesting, F. Erdmann, M. Doengi, S. Kügler & H.-C. Pape,
    Increased GABAergic efficacy of central amygdala projections to neuropeptide neurons in the brainstem during fear memory retrieval. Neuropsychopharmacoloy, 40, 2753-2763 (2015).
  14. P. Blaesse, L. Goedecke, M. Bazelot, M. Capogna, H.-C. Pape & K. Jüngling,
    µ-opioid receptor-mediated inhibition of intercalated neurons and impact on synaptic transmission to the central amygdala. J. Neurosci. 35, 7317-7325 (2015).
  15. M. Cerina, H.J. Szkudlarek, P. Coulon, P. Meuth, T. Kanyshkova, X.V. Nguyen, K. Göbel, T. Seidenbecher, S.G. Meuth, H.-C. Pape & T. Budde,
    Thalamic Kv 7 channels: pharmacological properties and activity control during noxious signal processing. Br. J. Pharmacol. 172, 3126-3140 (2015).
  16. J.R. Neumann, S. Dash-Wagh, K. Jüngling, T. Tsai,  M. Meschkat, A. Räk, C. Riedel, M.I.K. Hamad , S. Wiese, H.-C. Pape, K. Gottmann, M.R. Kreutz & P. Wahle,
    Y-P30 promotes axonal growth by stabilizing growth cones. BrainStructureFunction 220, 1935-1950 (2015).
  17. P. Bista, M. Pawlowski1, M. Cerina, P. Ehling, M. Leist, P. Meuth, A. Aissaoui1, M. Borsotto, C. Heurteaux, N. Decher, H.-C. Pape, D. Oliver, S.G. Meuth & T. Budde1,
    Differential phospholipase C-dependent modulation of TWIK-related acid-sensitive K+ (TASK) and TWIK-related K+ (TREK) channels in rat thalamocortical relay neurons. J. Physiol. (Lond.) 593, 127-144 (2015).
  18. H. Romo-Parra, P. Blaesse, L. Sosulina & H.-C. Pape,
    Neurosteroids increase tonic GABAergic inhibition in the lateral section of the central amygdala in mice. J. Neurophysiol. 113, 3421-3431 (2015).
  19. F. Erdmann, S. Kügler, P. Blaesse, M.D. Lange, B.V. Skryabin, H.-C. Pape & K. Jüngling,
    Neuronal expression of the human Neuropeptide S Receptor NPSR1 identifies NPS-induced calcium signaling pathways. PLoS One, 2015 Feb 25;10(2):e0117319. doi: 10.1371/journal.pone.0117319. 
  20. L. Sosulina, C. Strippel, H. Romo-Parra, T. Kanyshkova, S. Sartori, N. Singewald & H.-C. Pape,
    Substance P excites GABAergic neurons in the mouse central amygdala through neurokinin 1 receptor activation. J. Neurophysiol. 114, 2500-2508 (2015).
  21. S. Guggenhuber, H. Romo-Parra, L. Bindila, R. Lerner, M. Klugmann, H.-C. Pape & B. Lutz,
    Impaired 2-AG signaling at hippocampal glutamatergic synapses leads to aggravated anxiety-like behavior, but unaltered seizure susceptibility. Int J Neuropharmacol, in press (2015).
  22. T. Daldrup, J. Remmes, J. Lesting, S. Gaburro, M. Fendt, P. Meuth, V. Kloke, H.-C. Pape & T. Seidenbecher,
    Expression of freezing and fear-potentiated startle during sustained fear in mice. Genes, Brain and Behavior 14, 281-291 (2015).


  23. G. Born, D. Breuer, S. Wang, A. Rohlmann, P. Coulon, P. Vakili, C., F. Kiefer, M. Heine, H.-C. Pape & M. Missler,
    Modulation of synaptic function through the α-neurexin-specific ligand Neurexophilin-1. Proc. Natl. Acad. Sci. USA 111, E1274-1283 (2014).
  24. M.D. Lange, K. Jüngling, L. Paulukat, M. Vieler, S. Gaburro, L. Sosulina, P. Blaesse, H.K. Sreepathi, F. Ferraguti & H.-C. Pape,
    Glutamic acid decarboxylase 65: a link between GABAergic synaptic plasticity in the lateral amygdal and conditioned fear generalization. Neuropsychopharmacology 39: 2211-2220 (2014).
  25. T. Kanyshkova, P. Ehling, M. Cerina, P. Meuth, M. Zobeiri, S.G. Meuth, H.-C. Pape & T. Budde,
    Regionally specific expression of high-voltage-activated calcium channels in thalamic nuclei of epileptic and non-epileptic rats. Mol. Cell. Neurosci. 61, 110-22 (2014).
  26. M.P. Kummer, T. Hammerschmidt, A. Martinez, D. Terwel, G. Eichele, A. Witten, S. Figura, M. Stoll, S. Schwartz , H.-C. Pape, J.L. Schultze, D. Weinshenker & M.T. Heneka,
    Ear2 deletion causes early memory and learning deficits in APP/PS1 mice. J. Neurosci. 34, 8845-8854 (2014).

  27. S. Ruehle, F. Remmers, H. Romo-Parra, F. Massa, M. Wickert, S. Wärtge, M. Häring, N. Kaiser, G. Marsicano, H.-C. Pape & B. Lutz,
    Genetic rescue of the cannabinoid CB1 receptor in cortical glutamatergic circuits reveals region- and function-dependent sufficiency. J. Neurosci. 33, 10264-10277 (2013).
  28. J. Haaker, S. Gaburro, A. Sah, N. Gartmann, T.B. Lonsdorf, K. Meier, N. Singewald, H.-C. Pape, F. Morellini & R. Kalisch,
    A single dose of L-DOPA makes extinction memories context-independent and prevents the return of fear. Proc. Natl. Acad. Sci. USA 110, E2428-2436 (2013).
  29. T. Hammerschmidt, M.P. Kummer, D. Terwel, A. Martinez, A. Gorji, , K.S. Rommelfanger, J.P. Schroeder, M. Stoll, J. Schultze, G. Eichele, H.-C. Pape, D. Weinshenker & M.T. Heneka,
    Selective loss of noradrenaline exacerbates early cognitive dysfunction and synaptic deficits in APP/PS1 mice. Biol. Psychiatry 73, 454-463 (2013).
  30. S.G. Meuth, K. Göbel, T. Kanyshkova, P. Ehling, M.A. Ritter, W. Schwindt, M. Bielaszewska, P. Lebiedz, P. Coulon, A.M. Herrmann, W. Storck, J. Müthing, H. Pavenstädt, T. Kuhlmann, H. Karch, G. Peters, T. Budde, H. Wiendl & H.-C. Pape,
    Thalamic involvement in patients with neurologic impairment due to shiga toxin-producing E. coli. Ann. Neurol 73, 419-429 (2013).
  31. J. Lesting, T. Daldrup, V. Narayanan, C. Himpe, T. Seidenbecher & H.-C. Pape,
    Directional theta coherence in prefrontal cortical to amygdalo-hippocampal pathways signals fear extinction. PLoS One 24; 8(10):e77707 (2013).

  32. K. Jüngling, X. Liu, J. Lesting, P. Coulon, L. Sosulina, R.K. Reinscheid & H.-C. Pape,
    Activation of neuropeptide S expressing neurons in the locus coeruleus by corticotropin-releasing factor.
    J. Physiol. 590, 3701-3717 (2012).
  33. M.D. Lange, M. Doengi, J. Lesting, H.-C. Pape & K. Jüngling,
    A novel form of heterosynaptic long-term potentiation at interneuron-principal-neuron synapses in the amygdala requires nitric oxide signalling.
    J. Physiol. 590, 131-143 (2012).
  34. F. Chauveau, M.D. Lange, K. Jüngling, J. Lesting, T. Seidenbecher & H.C. Pape,
    Prevention of stress-impaired fear extinction through neuropeptide S action in the lateral amygdala.
    Neuropsychopharmacology 37, 1588-1599 (2012).

  35. S. Graebenitz, O. Kedo, E.-J. Speckmann, A. Gorji, H. Panneck, V. Hans, N. Palomero-Gallagher, A. Schleicher, K. Zilles & H.-C. Pape,
    Interictal-like network activity and receptor expression in the epileptic human lateral amygdala.
    Brain 134: 2929-2947 (2011)
  36. N. Okamura, C. Garau, D.M. Duangdao, S.D. Clark, K. Jüngling, H.-C. Pape &  R. K. Reinscheid,
    Neuropeptide S enhances memory consolidation and interacts with noradrenergic systems in the brain.
    Neuropsychopharmacology 36: 744-752 (2011).
  37. A. Gorji, C. Mittag, P. Shahabi, T. Seidenbecher & H.-C. Pape,
    Seizure-related activity of intralaminar thalamic neurons in a genetic model of absence epilepsy.
    Neurobiol. Dis. 2011 Mar 31 [Epub ahead of print].
  38. K. Kamprath, H. Romo-Parra, M. Häring, S. Gaburro, M. Döngi, B. Lutz & H.-C. Pape,
    Short-term adaptation of conditioned fear responses through endocannabinoid signaling in the central amygdala.
    Neuropsychopharmacology 36: 652-663 (2011).

  39. H.-C. Pape & D. Paré,
    Plastic synaptic networks of the amygdala for the acquisition, expression, and extinction of conditioned fear.
    Physiol. Rev. 90, 419-463 (2010).
  40. L. Sosulina, S. Graebenitz, H.-C. Pape.
    GABAergic interneurons in the mouse lateral amygdala: a classification study. J. Neurophysiol. 104, 617-626 (2010).

  41. P. Coulon, D. Herr, T. Kanyshkova, P. Meuth, T. Budde & H.-C. Pape,
    Burst discharges in neurons of the thalamic reticular nucleus are shaped by calcium-induced calcium release.
    Cell Calcium 46: 333-346 (2009).
  42. M. Döngi, P. Coulon, H.-C. Pape, J.W. Deitmer & C. Lohr,
    GABA uptake-dependent Ca2+ signaling in olfactory bulb astrocytes.
    Proc. Natl. Acad. Sci USA 106, 17570-17575 (2009)
  43. T. Kanyshkova, M. Pawlowski, P. Meuth, R. Bender, A. Brewster, A. Baumann, C. Dubé, T.Z. Baram,  H.-C. Pape & T. Budde
    Postnatal expression pattern of HCN channel isoforms in thalamic neurons: relationship to maturation of thalamocortical oscillations.
    J. Neurosci, 29: 8847-8857 (2009).
  44. S. Sangha, R.T. Narayanan, J.R. Bergado-Acosta, O. Stork, T. Seidenbecher & H.-C. Pape,
    Deficiency of the 65-kDa isoform of glutamic acid decarboxylase impairs extinction of cued but not contextual fear memory.
    J. Neurosci., 29: 15713-15720 (2009).

  45. K. Jüngling, T. Seidenbecher, L. Sosulina, J. Lesting, S. Sangha, S. Clark, N. Okamura, D. Duangdao, Y.-L. Xu, R. Reinscheid, H.-C. Pape
    Neuropeptide S-mediated control of fear expression and extinction: role of intercalated GABAergic neurons in the amygdala.
    Neuron 59: 298-310 (2008).
  46. C. Kluge, C. Stoppel, C. Szinyei, O. Stork, H.-C. Pape
    Role of the somatostatin system in contextual fear memory and hippocampal synaptic plasticity.
    Learn. Memory, 15: 252-260 (2008).
  47. P. Landgraf, P. Wahle, H.-C. Pape, E.D. Gundelfinger, M.R. Kreutz
    The survival-promoting peptide Y-P30 enhances binding of Pleiotrophin to Syndecan-2 and -3 and supports its neuritogenic activity.
    J. Biol. Chem., 283: 25036-25045 (2008). 
  48. L. Sosulina, G. Schwesig, G. Seifert, H.-C. Pape
    Neuropeptide Y activates a G-protein-coupled inwardly rectifying potassium current and dampens excitability in the lateral amygdala.
    Mol. Cell. Neurosci., 39: 491-498 (2008).

  49. S. Meis, T. Munsch, L. Sosulina, H.-C. Pape
    Postsynaptic mechanisms underlying responsiveness of amygdaloid neurons to cholecystokinin are mediated by a transient receptor potential-like current.
    Mol. Cell. Neurosci., 35: 356-367 (2007).
  50. R.T. Narayanan, T. Seidenbecher, C. Kluge, J. Bergado, O. Stork, H.-C. Pape
    Dissociated theta synchronization in amygdalo-hippocampal circuits during various stages of fear memory.
    Eur. J. Neurosci., 25 (6), 1823–1831 (2007).
  51. C. Szinyei, R.T. Narayanan, H.-C. Pape
    Plasticity of inhibitory synaptic network interactions in the lateral amygdala upon fear-conditioning in mice.
    Eur. J. Neurosci., 25, 1205-1211 (2007).

  52. K. Hüttmann, D. Yilmazer-Hanke, G. Seifert, J. Schramm, H.-C. Pape, & C. Steinhäuser
    Molecular and functional properties of neurons in the human lateral amygdala.
    Mol. Cell. Neurosci. 31, 210-217 (2006).
  53. T. Kanyshkova, S.G. Meuth, P. Meuth, T. Munsch, A. Ludwig, F. Hofmann, H.-C. Pape & T. Budde
    Impact of the functional interaction of TASK3 and HCN2 channels on the membrane resting conductance in thalamocortical relay neurons.
    J. Neurophysiol. 96, 1517-1529 (2006).
  54. S.G. Meuth, I.M. Aller, T. Munsch, T. Schuhmacher, T. Seidenbecher, P. Meuth, C. Kleinschnitz, H.-C. Pape, H. Wiendl, W. Wisden & T. Budde     The contribution of TASK-1-containing channels to the function of dorsal lateral geniculate thalamocortical relay neurons.
    Mol. Pharmacology. 69, 1468-1476 (2006).
  55. B. Musset, S.G. Meuth, G.X. Liu, C. Derst, S. Wegner, H.-C. Pape, T. Budde, R. Preisig-Müller, J. Daut
    Effects of divalent cations and spermine on the K+ channel TASK-3 and on the outward current in native thalamic neurons
    J. Physiol. 572, 639-657 (2006). 

  56. T. Budde, L. Caputi, T. Kanyshkova, R. Staak, C. Abrahamczik, T. Munsch, H.-C. Pape
    Impaired regulation of thalamic pacemaker channels through an imbalance of subunit expression in absence epilepsy.
    J. Neurosci. 25, 9871-9882 (2005).
  57. P. Landgraf, F. Sieg, P. Wahle, M.R. Kreutz, H.-C. Pape
    A maternal blood-borne factor promotes survival of the developing thalamus. FASEB J.19, 255-227 (2005).
  58. H.-C. Pape
    GABAergic neurons: gate masters of the amygdala, mastered by dopamine.
    Neuron 48, 877-879 (2005).
  59. H.-C. Pape, R.T. Narayanan, J. Smid, O. Stork, T. Seidenbecher
    Theta activity in neurons and networks of the amygdala related to long term fear memory.
    Hippocampus 15, 874-880 (2005).

  60. S.G. Meuth, T. Budde, T. Kanyshkova, T. Broicher, T. Munsch & H.-C. Pape,
    Contribution of TWIK-related acide-sensitive K+ channel 1 (TASK1) and TASK3 channels to the control of activity modes in thalamocortical neurons.
    J. Neurosci. 23, 6460-6469 (2003).
  61. T. Munsch, M. Freichel, V. Flockerzi & H.-C. Pape,
    Contribution of transient receptor potential channels to the control of GABA release from dendrites.
    Proc. Natl. Acad. Sci. USA 100, 16065-16070 (2003).
  62. T. Seidenbecher, T.R. Laxmi, O. Stork & H.-C. Pape,
    Amygdalar and hippocampal theta rhythm synchronization during fear memory retrieval.
    Science 301, 846-850 (2003).
  63. C. Szinyei, O. Stork & H.-C. Pape,
    Contribution of NR2B subunits to synaptic transmission in amygdaloid interneurons.
    J. Neurosci. 23, 2549-2556 (2003).