In detail, we are interested in answering the following fundamental questions:
- How can cells control and tune their mechanical properties?
- How do cells mechanically interact in development, immune response and cancer progression?
- What intracellular forces and mechanical changes happen during cell migration and cytokinesis?
- What new statistical mechanics models can explain cytoskeletal mechanics and organization?
To answer these questions we aim at a detailed physical description of the mechanical processes that are used by living cells. For this we continuously develop new measurement techniques such as optical tweezers, high accuracy particle tracking, traction force microscopy, micropipette aspiration and UV laser ablation.