Biomedical Informatics

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The main focus of our work lies in the analysis of next-generation sequencing data for the detection of disease-related DNA mutations and epigenetic modifications. Our aim is to help to improve the understanding, diagnosis and treatment of cancer and leukemia in particular.

Using computational and statistical methods, we analyse whole-genome, whole-exome and targeted sequencing data, as well as ChIP-, RNA-, 4C- and STARR-seq datasets.