Videos of the Medical Faculty of the Uni Münster

A video says more than a 1,000 words. Therefore, the Faculty of Medicine at the WWU regularly illustrates subject matter from both education and research through film. In this way, complex topics are made comprehensible.
This page offers an overview of films commissioned by the faculty and those projects produced in cooperation with the faculty. Tip: An extended collection of videos concerning various departments from the University of Münster can be found in the WWU-Videoportal.

Medical Research at the University of Münster: The Faculty - the Film

The video was shot over the course of a year; the result is eleven minutes of concise film sequences. This may seem like a scant amount of time to de­li­ver an insight into the medical research done at the University of Münster, which con­sti­tutes a team of more than 2,000 individuals. Instead of delivering cold facts, "the faculty - the film" therefore fo­cus­es on the attributes of university medicine in Mün­ster.
To the video

A nearly forgotten genius: Film portrait of the Nobel Prize winner Gerhard Domagk

With the discovery of the anti­bac­te­ri­al effect of the sul­fon­amides, he saved millions of lives, yet he is barley known out­side of his scientific spe­cial­ty: Prof. Gerhard Domagk. The elaborate film illustrates the life and work of this important researcher, who is to date the only Nobel Prize laureate from the University of Münster. To the video

The Studienhospital Münster - a "simulated teaching hospital"

In the Studienhospital Münster, medical students are prepared for the environment, which they can later expect in their careers. Mistakes will be made during the first few semesters, because the ultimate goal during this time is not the correct diagnosis, but rather the development of the clinical process leading to diagnosis. To the video

The research focus neural systems

The research of neural systems covers the functions of ion chan­nels and signaling mo­le­cules as well as in­flam­ma­to­ry diseases such as multiple scle­ro­sis. In addition, mechanisms of fear, anxiety and anxiety disorders, as well as other psychiatric and psychotherapeutic aspects are investi­gated. To the video

Understanding the concepts of cell movement: Zebrafish as a transparent model organism

The literal transparency of ze­bra­fish facilitates the vi­su­al­iza­tion of processes of cell move­ment within our bodies; the fish are transparent in the early sta­ges of development. Sargon Yigit explained how this knowledge can be used by sci­en­tists in a live-streaming session during the "Science Day" from the Medical Faculty of Münster. To the Video

Mass spectrometry using the MALDI method

Biomolecules such as vitamins, carbohydrates and hormones play a central role in many life pro­cess­es. One way to visualize these substances - and thus to better understand the pro­cess­es that occur in cells and organs - is the still relatively new method of matrix-assisted laser desorption / ionization mass spectrometry imaging. To the Video

Assessing parotid tumors

Malignant tumors of the parotid (parotid gland) can be divided into a variety of subgroups. The correct assignment is helpful in determining the most effective treatment. In her doctoral the­sis, Dr. Alina Busch investigated molecular factors that en­able the differentiation of these tumor types. To the Video

Stem cell differentiation in the brain

The regenerative capabilities of our brains are based on the proliferation of specialized cells originating from stem cells. Dr. Eva Christine Bunk gained valuable insights into stem cell differentiation within various areas of the brain, which are of potential use in designing therapeutic ap­proaches to neurodegenerative diseases. To the Video

Efficacy prognosis via AP-Bounce

A new drug aimed at helping patients with advanced prostate cancer resistant to hormone therapy will soon be available. In some cases the drug works well, but for others, it is less effective. What factors control this efficacy? This question is answered by Dr. Phillip Mikah's research. To the video

Potassium channels in muscle cells

Musculoskeletal cells arise from the fusion of individual muscle fibers and can re­con­nect following injuries or in­flam­ma­tion; in doing so, they regenerate. How does this pro­cess function and what role do two-pore potassium chan­nels (K2P channels) play? Dr. Ali Afzali addresses these questions in his research. To the video

Cancer prognosis using macrophages

Tumors do not consist solely of a formation of tumor cells. Im­mune cells have been shown to participate early in the process. Thus a characteristic "tumor­milieu" is formed, which pro­motes the spread of metastases. In her doctoral thesis Dr. Anne Becker investigated the influence of macrophage ac­tiv­i­ty on the growth of tumor cells. To the video

Early detection of inflammatory diseases

The use of contrast media is common in medical imaging. Dr. Tom Völler used a newly developed substance for in­ves­ti­ga­tions within the scope of his doctoral thesis. This resulted in a more specific representation of inflammations. It was thus possible to measure the cur­rent strength of in­flam­ma­tion. To the video

Tumor control with RTK

Receptor tyrosine kinases (RTK) are proteins on the cell mem­brane, which direct signals from the body to the cell in­te­ri­or. They are responsible, among other things, for cell growth and migration. Dr. Amélie Tillmanns researched the role of RTK in Ewing sarcoma and its impact on the aggressiveness of the tumors. To the video

Salt-induced cell stiffening

Endothelial cells line every blood vessel in the car­dio­vas­cu­lar system and thereby trans­port essential sodium into the cell via so-called endothelial sodium channels (EnNaC). As the sodium concentration increases these chan­nels can develop a negative property. Dr. Moritz Alexander Paar investigated to what extent this endothelial dysfunction and the sensitivity of an organism to sodium increase with age. To the video

Cell binding in pancreatic carcinoma

Dr. Hannah Listing researched the dissemination of pancreatic carcinoma in the abdomen. In experiments in the Petri dish, she was able to observe that the pancreatic cancer cells develop differently when interacting with the cells of the ab­do­men. To the video

Dangerous metabolic disease decrypted: PGM1 deficiency

Mutations of the human gene phosphoglucomutase 1 (PGM1) lead to a deficiency of the en­zyme of the same name. That can have serious con­se­quen­ces: muscle dys­func­tion, a dan­ger­ous­ly low blood glucose or a severe car­diac mus­cle disease are among the possible com­pli­ca­tions. Dr. Laura Tegtmeyer researched PGM1 deficiency. To the video

Human salt sesitivity test

In the future, the salt blood test "SBT-mini" could become an integral part of a home phar­ma­cy. With this self-monitoring test the individual sensitivity to salt can be quickly and easily determined and thus an unhealthy dient can be avoided. To the video

Drug iBET could help children with cancer

A new drug could help treat can­cer in children in the long term: neuroblastomas, me­dul­lo­blas­tom­as and rhabdoid tu­mor cells die in the petri dish when iBET is administered. Dr. Annabelle Zoghbi received the Maria-Möller-Prize for her dissertation, in which she showed an iBET mechanism of action in neuroblastomas. To the video

Test tube vs real life trial: Why a drug for arthritis failed

Promising in the test tube, use­less in the body: The hope to use a leukemia drug to also treat rheumatoid arthritis came up empty. Dr. Schmidt-Lauber revealed that this is due to the transport of the active substance into the cell; the Med­i­cal Faculty of Münster awarded him a doctoral prize. To the video

New MRFT procedure facilitates metastasis observation

Aggressive children's cancer: Dr. Lennart Liebsch investigated how the spread of Ewing's sar­co­ma can be documented - and found a new method of mag­net­ic resonance tomography, with which metastases can be observed (at least in mice). To the video

Blocking protein function inhibits bone loss

Our bones constantly change, within ten years the human skeleton is completely re­newed. However, for many el­der­ly people the dynamics be­tween bone mass and bone loss is out of balance, and the disease osteoporosis often leads to fractures. Dr. Daniel Umlauf discovered a possible new treatment approach. To the video

Acute lymphoblastic leukemia: Immunotherapy

The most common type of can­cer in children and adolescents is acute lymphoblastic leu­ke­mia (ALL) and can be cured with chemotherapy in 80 percent of patients. In her dissertation, Dr. Imke Lustfeld investigated the question of why some chil­dren respond better to therapy than others. To the video

The genetics of atrial fibrillation

About 1.8 million people in Ger­many suffer from cardiac ar­rhyth­mia. The precise de­vel­op­ment of this disorder remains unknown. There are sug­ges­tions that certain genetic ab­nor­mal­i­ties were associated with pre-fibrillation, although there had not been any biological evidence. Dr. Peter C. Kahr provided new information. To the video

Targeted attack: Using a fusion protein as a gentle drug for cancer

tTF-NGR is a fusion protein that precisely targets tumors and pre­vents the destruction of oth­er tissue. Dr. Johannes Drei­scha­lück tested this novel ap­proach in his doctoral thesis. He was able to detect binding of the tTF-NGR in the blood vessels of tumors. With only minimal side effects, this protein could be made available as a gentle cancer drug for clinical practice. To the video

From repressors to sensitizers: Better understanding the forms of anxiety management

Certain sounds, odors, or facial expressions can be stimuli that evoke strong aversions. Dr. Vic­to­ria Paul investigated the dif­fer­ences in how women pro­cess these stimuli in her award-winning dissertation. She found two types: repressors avoid negative stimuli as often as possible, but sen­si­ti­zers pay particular attention to threatening stimuli. To the video

What could the Roman river warships do? Getting the sport medicine physicians on board

The Varus battle is best known, but the journey of the Roman le­gions upstream to our region is not. The performance of Roman inland vessels was therefore the focus of a spectacular pro­ject: During a race, two replicas competed against one another. To the video

Fighting leukemia cells during the early stages: Using Inca1 as leverage

Leukemia cells can be treated well with chemotherapy. But often the disease relapses, due to the fact that in early the de­vel­op­ment stage – as stem cells – the cancer cells can resist treat­ment. Proteins such as Inca1 could be used in an approach to eliminate these cells in that stage. To the video

Immune System: How do macrophages find their targets?

They are indispensable for the human immune system: sca­ven­gers. They can render bacteria in infected tissue harmless. But how do the macrophages find their way to inflammation? A response to this research question is provided by the dissertation of Dr. Moritz Kronlage. To the video

Chronic inflammatory vascular disease: Why cortisone doesn't usually help

Cortisone relieves symptoms in most chronic inflammatory dis­eases and contributes to re­cov­ery. However, in the case of a chronic inflammatory vascular disease (vasculitis), therapy with only this agent is not sufficient. Why are vascular cells resistant? Dr. Paola Koenen has published an ex­pla­na­tion at the molecular level. To the video

Immune defense for bone cancer: Premier promotion via regulatory T-cells

Tumors arise from altered cells, but they are rarely recognized and combated by the immune system. In his doctorate, Dr. Peter Brinkrolf investigated whether the body’s own de­fens­es against Ewing sarcoma are slowed by regulatory T-cells. To the video

The role of the hormone vasopressin in diabetic insipidus

The human body couldn't func­tion without os­mo­re­gu­la­tion. In his award-winning dis­ser­ta­tion, Dr. Markus Rinschen in­ves­ti­gat­ed the disturbance of os­mo­re­gu­la­tion in a particular form of diabetes and the role of the hormone va­so­pres­sin. To the video

Stealth bacteria: How S. aureus tricks antibiotics

The bacterium Staphylococcus aureus not only causes strong inflammatory effects during infection, but can also hide in the host cells over a longer period of time. Protected from both the immune system and from many antibiotics, these bacteria can be the source of chronic infections. To the video

The underestimated danger

For a few centuries it has been indispensable to our cooking: salt. Few of us know how many grams of the "white gold" we ingest every day - let alone how much is actually healthy. The physiologist Hans Oberleithner explains. To the video

Children's feet

Feet are the most heavily used parts of the body – they bear all our weight. The "Kidfoot Mün­ster" study at the Department of Motion Analysis of the Medical Faculty in­ves­ti­gates the de­vel­op­ment of the human foot beginning at infancy. To the video

The "imposter" patient

The reliable diagnosis of psy­cho­so­ma­tic complaints is a par­tic­u­lar challenge for medical students in training. Prof. Ge­re­on Heuft and his team de­vel­oped a new teaching concept, in which actors tell the life stories of traumatized patients during therapy. To the video

Anxiety research

Fear and anxiety protect people from dangerous situations. However, if these mechanisms are out of balance, they are referred to as anxiety disorders. At the Institute of Physiology I, Prof. Pape and his team investigate how mis-programmed fears can be forgotten in mice. To the video