Antivenomenous compounds in Strophanthus sarmentosus DC (Apocyaneceae)
Collaboration with J. Abiola (DAAD fellow) from the University of Ibadan, Nigeria
Database of Insect Adipokinetic Hormones
König S, Marco H, Gäde G (2022) The proline effect and the tryptophane immonium ion assist in de novo sequencing of adipokinetic hormones. submitted
Download: AKH_DBv1_15112022.xlsx
Graduate School of Natural Products (GS-NP)
A highly interdisciplinary program among the Faculties of Biology, Chemistry, Pharmacy, and Medicine to strengthen cutting-edge research on natural products.
Start March 2022
Gastric Cancer Prediction Model
Aziz S, König S, Umer M, Akhter TS, Iqbal S, Ibrar M, Ur-Rehman T, Ahmad T, Hanafiah A, Zahra R, Rasheed F. (2023) Risk factor profiles for gastric cancer prediction with respect to Helicobacter pylori: A study of a tertiary care hospital in Pakistan. Artif Intell Gastroenterol 4(1), dx.doi.org/10.35712/aig.v4.i1.0000
GUI executable file archive, Vs. 06 for Windows 10:
Gastric_Cancer_GUI_Executable_File_version_06.part1.rar
Gastric_Cancer_GUI_Executable_File_version_06.part2.rar
Gastric_Cancer_GUI_Executable_File_version_06.part3.rar
(unpack, e.g. with 7-Zip or WinRAR, and then run ML_Model_Gastric_cancer.exe)
Identification and characterization of gastric cancer biomarkers in Helicobacter pylori infected patients
Scholarship for S. Aziz from the Higher Education Commission of Pakistan (2021-2022)
Aziz S, Rasheed F, Zahra R, König S. (2022) Gastric cancer pre-stage detection and early diagnosis of gastritis using serum protein signatures. Molecules 27:2857
Aziz S, König S, Noor H, Nadeem M, Zahra R, Rasheed F (2022) Isolated dextrogastria with eventration of right hemidiaphragm and hiatal hernia in an adult male. BMC Gastroenterology 22:56
Zusammenarbeit mit der Universität Rijeka, Kroatien
Die Core Unit arbeitet gemeinsam mit Prof. Sandra Kraljevic Pavelic vom Institut für Biotechnologie an einem Projekt zur Proteinanalyse von Istrischen Rohschinken. (2019)
Zusammenarbeit mit der Neurochirurgie am UKM (2020-2022)
Determination of protoporphyrin IX in blood of glioblastoma patients
A. Walke, E. Suero Molina, W. Stummer, S. König. “Protoporphyrin IX analysis from blood and serum in the context of neurosurgery of glioblastoma.” In: Mass Spectrometry, Ed. G. Mitulovic, IntechOpen, London, 2020, doi.org/10.5772/intechopen.95042
Black D, Kaneko S, Walke A, König S, Stummer W, Suero Molina E. (2021) Characterization of autofluorescence and quantitative protoporphyrin IX biomarkers for optical spectroscopy-guided glioma surgery. Sci Rep 11, 20009
Walke A, König S. (2021) Protorphyrin IX purification from blood and serum for mass analysis – considerations with respect to neurosurgery. RCM, DOI:10.1002/rcm.9138
Collaboration with the Stradina University of Riga
The Core Unit collaborates with Prof. Zanda Daneberga of the Institute for Oncology on the project "Prolonged hypoxia induced differential protein signatures in BRCA1 +/- triple negative breast cancer cell lines", funded by the Baltic-German University Liaison Office. (2019)
EUTRAIN
CUP participates in the European Translational Training for Autoimmunity & Immune Manipulation Network EUTRAIN, a research and training Marie Curie Initial Training Network (ITN) focused on translational research in pediatric rheumatology.
EUTRAIN Network
EUTRAIN Network
The German Research Foundation DFG funds a 3-year collaboration of the universities of Mainz and Münster for studies of the complex-regional pain syndrome with 459800 € (2012-2015)
The complex-regional pain syndrome (CRPS) is a neurological-orthopedic-traumatologic pain disease, which develops in approximately 5% of patients for instance after bone fracture. These patients observe, e.g., overheating in the respective limbs, edema, excessive sweating and pain during movement
The aim of the projectes of the physician from Mainz, Frank Birklein, and the chemist / bioanalytician from Münster Simone König is to investigate the inflammatory processes in tissue such as skin and assign them to clinical symptoms in order to prepare for targeted therapy of CRPS.
News Medical Faculty
Juraforum
Development of a reference collection for gas phase fragmentation data
TransEuropean Footrace 2009: Urine profiling
In collaboration with medical doctors from Basel and Ulm the Proteomics group of the IFG works on the analysis of urine samples from marathon runners to elucidate performance-specific markers. Link
BMC Medicine
BMC Medicine
Silkworm Proteomics 2010-2012
Funding of DFG and DAAD allows the collaboration with Prof. M. Krishnan of Bharathidasan University, Tiruchirappalli, India, for the investigation of different silkworm proteins.
News Medical Faculty
IDW
BMBF (ProINNO) Project 2007-2010
For a collaboration with a small company, Eco Luft- und Raumqualität, Cologne, a project was funded which deals with the identification of protein allergens in dust at the workplace. 25 Mio people suffer from allergies in Germany. Bakers allergy is an allergic skin irritation or even asthma, which is caused by high-molecular compounds in flour, yeast or other components in the air of bakeries. It is recognized as an occupational disease. InfosBased on the methods of proteomics, gel electrophoresis and mass spectrometry, in this project a web-based database will be built which will allow the screening of allergens at the workplace in order to improve prevention.
Phoshorylation of annexin 2
Innovative Medical Research of the Medical Faculty Münster sponsors the collaboration of Ursula Rescher (ZMBE) and Simone König (IFG) for two years. The phosphorylation sites of annexin 2 and their importance in insulin-induced signal transduction shall be investigated.