Cristin Brand

Centre of Reproductive Medicine and Andrology
Albert-Schweitzer-Campus 1, Geb. D11
48149 Münster, Germany
Tel. +49 (0)251 83-52043
E-Mail  Cristin Brand

 

  • Research interests:

    Klinefelter syndrome (KS) is defined by a supernumerary X chromosome which leads to infertility and an impaired endocrine phenotype in 1-2 out of 1000 men. In addition, further comorbidities such as infarction risk, reduced diameter of arteries and cardiovascular problems have been described recently.

    This project focuses on the vascularization of different organs and the testicular endocrine signaling in human KS and the corresponding mouse model (41,XXY*). The option of combining the model with clinical aspects in a translational PhD work is an unique possibility at CeRA which allows the evaluation of certain features of KS during development experimentally.

  • Scientific career

    Since Aug 2015 PhD student at the Centre of Reproductive Medicine and Andrology, Wistuba Lab, experimental translational work in the field of Klinefelter Syndrome (patient and mouse model)
    Feb - Dec 2015 Research assistant at the Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, AG Pleger
    Sep 2012 - Aug 2014 Master of molecular biomedicine Stays abroad: 10/2013-08/2014 Buffalo, USA; 04-06/2013 Bern, Swiss
    Okt 2009 – Aug 2012 Bachelor of life science Bachelor thesis at the Max-Planck-Institut for molecular biomedicine Stay abroad: 10/2011-02/2012 Hasselt, Belgium
  • Publications

    Wistuba J, Werler S, Lewejohann L, Brand C, Damm OS. Mouse models for the exploration of Klinefelter´s syndrome. In Conn MJ (ed) Animal models of human diseases; 2nd revised edition, Elsevier, 2017, in press
    Wistuba J, Brand C, Zitzmann M, Damm OS. Genetics of Klinefelter Syndrome: Experimental exploration. Monographs in Human Genetics, In Vogt PH (ed) Genetics of Male and Female Infertility, Karger, 2017, in press
    Kumar S, Grundeis F, Brand C, Hwang H-J, Mehnert J, Pleger B. 2016. “Differences in Insula and Pre-/Frontal Responses during Reappraisal of Food in Lean and Obese Humans.” Frontiers in Human Neuroscience 10 (May): 233. doi:10.3389/fnhum.2016.00233.
    Berman JM, Brand C, Awayda MS. 2015. “A Long Isoform of the Epithelial Sodium Channel Alpha Subunit Forms a Highly Active Channel.” Channels (Austin, Tex.) 9 (1): 30–43. doi:10.4161/19336950.2014.985478.