How do sperm find their way to the egg? Our primary research focus is to answer this fundamental question in reproductive research.
To this end, we investigate the complex interplay of receptors, ion channels, and chemical messengers that enable sperm to translate changes in their chemical and physical microenvironment into a behavioral response. From electrophysiology to fluorescent probes, high-speed motility studies, and protein biochemistry – we rely on a broad range of state-of-the-art methods to tackle this demanding task. For us, however, sperm are more than just a powerful model organism for basic research in cellular signal transduction: At the limits of our present knowledge about the molecular basics of human reproduction, we are looking for the answers behind unexplained male infertility.
Detailed informations about our research interests can be found here.