Publikationen

Balbach, M., Hamzeh, H., Jikeli, J. F., Brenker, C., Schiffer, C., Hansen, J. N., Neugebauer, P., Trötschel, C., Jovine, L., Han, L., Florman, H. M., Kaupp, U. B., & Strünker, T. (2020) "Molecular Mechanism Underlying the Action of Zona-pellucida Glycoproteins on Mouse Sperm." Frontiers in Cell and Developmental Biology, 8, 1–15. doi.org/10.3389/fcell.2020.572735
Wang, T., Young, S., Krenz, H., Tüttelmann, F., Röpke, A., Krallmann, C., Kliesch, S., Zeng, X., Brenker, C., & Strünker, T. (2020) "The Ca2+ channel CatSper is not activated by cAMP/PKA signaling but directly affected by chemicals used to probe the action of cAMP and PKA." Journal of Biological Chemistry. doi.org/10.1074/jbc.RA120.013218
Bollmann E, Schreiber JA, Ritter N, Peischard S, Ho HT, Wünsch B, Strünker T, Meuth S, Budde T, Strutz-Seebohm N, Seebohm G. (2020) "4,4'-Diisothiocyanato-2,2'-Stilbenedisulfonic Acid (DIDS) Modulates the Activity of KCNQ1/KCNE1 Channels by an Interaction with the Central Pore Region." Cell Physiol Biochem. 2020 Apr 8; 54(2):321332. doi.org/10.33594/000000222
Schiffer C, Rieger S, Brenker C, Young S, Hamzeh H, Wachten D, Tüttelmann F, Röpke A, Kaupp UB, Wang T, Wagner A, Krallmann C, Kliesch S, Fallnich C, Strünker T. (2020) "Rotational motion and rheotaxis of human sperm do not require functional CatSper channels and transmembrane Ca2+ signaling." EMBO J. (2020) Jan 39:e102363. doi.org/10.15252/embj.2019102363.
Trötschel C, Hamzeh H, Alvarez L, Pascal R, Lavryk F, Bönigk W, Körschen HG, Müller A, Poetsch A, Rennhack A, Gui L, Nicastro D, Strünker T, Seifert R, Kaupp UB (2019) "Absolute proteomic quantification reveals design principles of sperm flagellar chemosensation." EMBO J. (2019) Dec 27:e102723. doi.org/10.15252/embj.2019102723.
Raju DN, Hansen JN, Rassmann S, Stüven B, Jikeli JF, Strünker T, Körschen HG, Möglich A, Wachten D. (2019) "Cyclic Nucleotide-Specific Optogenetics Highlights Compartmentalization of the Sperm Flagellum into cAMP Microdomains." Cells. 27;8(7). doi.org/10.3390/cells8070648.
Lim S, Kierzek M, O'Connor AE, Brenker C, Merriner DJ, Okuda H, Volpert M, Gaikwad A, Bianco D, Potter D, Prabhakar R, Strünker T, O'Bryan MK. (2019) “CRISP2 Is a Regulator of Multiple Aspects of Sperm Function and Male Fertility.” Endocrinology. 160(4):915-924. doi.org/10.1210/en.2018-01076.
Amedonu E, Brenker C, Barman S, Schreiber JA, Becker S, Peischard S, Strutz-Seebohm N, Strippel C, Dik A, Hartung HP, Budde T, Wiendl H, Strünker T, Wünsch B, Goebels N, Meuth SG, Seebohm G, Melzer N. (2019) “An Assay to Determine Mechanisms of Rapid Autoantibody-Induced Neurotransmitter Receptor Endocytosis and Vesicular Trafficking in Autoimmune Encephalitis.” Front Neurol. 10:178. doi.org/10.3389/fneur.2019.00178.
Hamzeh H, Alvarez L, Strünker T, Kierzek M, Brenker C, Deal PE, Miller EW, Seifert R, Kaupp UB. (2019) “Kinetic and photonic techniques to study chemotactic signaling in sea urchin sperm.” Methods Cell Biol. 151:487-517. doi.org/10.1016/bs.mcb.2018.12.001.
Brenker C, Rehfeld A, Schiffer C, Kierzek M, Kaupp UB, Skakkebæk NE, Strünker T (2018) "Synergistic activation of CatSper Ca2+ channels in human sperm by oviductal ligands and endocrine disrupting chemicals." Hum Reprod. 2018 Sep 5. doi.org/10.1093/humrep/dey275.
Windler F, Bönigk W, Körschen HG, Grahn E, Strünker T, Seifert R, Kaupp UB (2018). "The solute carrier SLC9C1 is a Na+/H+-exchanger gated by an S4-type voltage-sensor and cyclic-nucleotide binding." Nat Commun. 2018 Jul 18;9(1):2809. doi.org/10.1038/s41467-018-05253-x
Rennhack A, Schiffer C, Brenker C, Fridman D, Nitao ET, Cheng YM, Tamburrino L, Balbach M, Stölting G, Berger TK, Kierzek M, Alvarez L, Wachten D, Zeng XH, Baldi E, Publicover S, Kaupp UB, Strünker T (2018). "A novel cross-species inhibitor to study the function of CatSper Ca2+ channels in sperm." Br J Pharmacol. 2018 May 3. doi.org/10.1111/bph.14355
Brenker, C.* & Schiffer, C.*, Wagner I.V., Tüttelmann, F., Röpke, A., Rennhack, A., Kaupp, U.B., Strünker, T. (2018) "Action of steroids and plant triterpenoids on CatSper Ca2+ channels in human sperm." PNAS 115, E344-E346. doi.org/10.1073/pnas.1717929115 *Equal contribution.
Matschke V, Piccini I, Schubert J, Wrobel E, Lang F, Matschke J, Amedonu E, Meuth SG, Strünker T, Strutz-Seebohm N, Greber B, Scherkenbeck J & Seebohm G. (2017) "The Natural Plant Product Rottlerin Activates Kv7.1/KCNE1 Channels" Cell Physiol Biochem. 40(6), 1549-1558 doi.org/10.1159/000453205
Berger TK, Fußhöller DM, Goodwin N, Bönigk W, Müller A, Dokani Khesroshahi N, Brenker C, Wachten D, Krause E, Kaupp UB & Strünker T. (2016) "Post-translational cleavage of Hv1 in human sperm tunes pH- and voltage-dependent gating" J Physiol. doi.org/10.1113/JP273189
Kaupp UB & Strünker T. (2016) "Signaling in Sperm: More Different than Similar" Trends Cell Biol. 27(2), 101-109. doi.org10.1016/j.tcb.2016.10.002
Mukherjee S, Jansen V, Jikeli JF, Hamzeh H, Alvarez L, Dombrowski M, Balbach M, Strünker T, Seifert R, Kaupp UB, Wachten D. (2016) "A novel biosensor to study cAMP dynamics in cilia and flagella" eLife 5, e14052 doi.org/10.7554/eLife.14052
Strünker T., Alvarez, L. & Kaupp, U.B. (2015) "At the physical limit - chemosensation in sperm" Curr. Opin. Neurobiol. 34, 110-116 doi.org/10.1016/j.conb.2015.02.007
Strünker T., & Kaupp, U.B. (2015) "Larry Cohen-50 ways to DYE your science" Neurophotonics 2, 021004-021004 doi.org/10.1117/1.NPh.2.2.021004
Jansen, V., Alvarez, L., Balbach, M., Strünker T., Hegemann, P., Kaupp, U.B. & Wachten, D. (2015) "Controlling fertilization and cAMP signaling in sperm by optogenetics" eLife 4, e05161 doi.org/10.7554/eLife.05161
Seifert, R., Flick, M., Bönigk, W., Alvarez, L., Trötschel, C., Poetsch, A., Müller, A., Goodwin, N., Pelzer, P., Kashikar, N.D., Kremmer, E., Jikeli, J., Timmermann, B., Kuhl, H., Fridman, D., Windler, F., Kaupp, U.B. & Strünker T. (2015) "The CatSper channel controls chemosensation in sea urchin sperm" EMBO J. 34, 379-392 doi.org/10.15252/embj.201489376
Pichlo, M., Bungert-Plümke, S., Weyand, I., Seifert, R., Bönigk, W., Strünker, T., Kashikar, N.D., Goodwin, N., Müller, A., Pelzer, P., Van, Q., Enderlein, J., Klemm, C., Krause, E., Trotschel, C., Poetsch, A., Kremmer, E. & Kaupp, U.B. (2014) "High density and ligand affinity confer ultrasensitive signal detection by a guanylyl cyclase chemoreceptor" J. Cell. Biol. 206, 541-557 doi.org/10.1083/jcb.201402027
Schiffer, C., Müller, A., Egeberg, D.L., Alvarez, L., Brenker, C., Rehfeld, A., Frederiksen, H., Wäschle, B., Kaupp, U.B., Balbach, M., Wachten, D., Skakkebaek, N.E., Almstrup, K. & Strünker T. (2014) "Direct action of endocrine disrupting chemicals on human sperm" EMBO Rep., doi.org/10.15252/embr.201438869
Brenker, C., Zhou, Y., Muller, A., Echeverry, F.A., Trotschel, C., Poetsch, A., Xia, X.M., Bönigk, W., Lingle, C.J., Kaupp, U.B. & Strünker, T. (2014) "The Ca2+-activated K+ current of human sperm is mediated by Slo3" eLife 3, doi.org/10.7554/eLife.01438
Krähling, M., Alvarez, L., Debowski, K., Van, Q., Gunkel, M., Irsen, S., Al-Amoudi, A., Strünker, T., Kremmer, E., Krause, E., Voigt, I., Wörtge, S., Waisman, A., Weyand, I., Seifert, R., Kaupp, U.B. & Wachten, D. (2013) "CRIS- a novel cAMP-binding protein controlling spermiogenesis and the development of flagellar bending" PLoS Genetics, doi.org/10.1371/journal.pgen.1003960
Brenker, C., Goodwin, N., Weyand, I., Kashikar, N. D., Naruse, M., Krahling, M., Muller, A., Kaupp, U. B. & Strünker, T. (2012) "The CatSper channel: a polymodal chemosensor in human sperm" EMBO J.31, 1654-1665 doi.org/10.1038/emboj.2012.30
Strünker, T. (2012) "A unique K+-selective ion channel activated by a single cGMP molecule controls chemotaxis of sea urchin sperm" In: Morisawa, M. (ed.): Sperm Cell Research in the 21st Century: Historical Discoveries to New Horizons (Tokyo: Adthree Publishing Co.m Ltd), 142-145
Strünker, T., Goodwin, N., Brenker, C., Kashikar, N.D., Weyand, I., Seifert, R. & Kaupp, U.B. (2011) "The CatSper channel mediates progesterone-induced Ca2+ influx in human sperm" Nature 471, 382-386 doi.org/10.1038/nature09769
Bönigk, W., Loogen, A., Seifert, R., Kashikar, N., Klemm, C., Krause, E., Hagen, V., Kremmer, E., Strünker, T., & Kaupp, U.B. (2009) "An atypical CNG channel activated by a single cGMP molecule controls sperm chemotaxis" Science Signal. 2, doi.org/10.1126/scisignal.2000516
Schröder-Lang, S., Schwärzel, M., Seifert, R., Strünker, T., Kateriya, S., Looser, J., Watanabe, M., Kaupp, U.B., Hegemann, P. & Nagel, G. (2007) "Fast manipulation of cellular cAMP level by light in vivo" Nature Methods 4, 39-42 doi.org/10.1038/nmeth975
Strünker, T., Weyand, I., Bönigk, W., Van, Q., Loogen, A., Brown, J.E., Kashikar, N., Hagen, V., Krause, E. & Kaupp, U.B. (2006) "A K+-selective cGMP-gated ion channel controls chemosensation of sperm" Nature Cell Biology 8, 1149-1154 doi.org/10.1038/ncb1473
Balfanz, S.*, Strünker, T.*, Frings, S. & Baumann, A. (2005) "A family of octopamine receptors that specially induce cyclic AMP production or Ca2+ release in Drosophila melanogaster" J. Neurochem. 93, 440-451 doi.org/10.1111/j.1471-4159.2005.03034.x
Grohmann, L., Blenau, W., Erber, J., Strünker, T., & Baumann, A. (2003) "Molecular and functional characterization of an octopamine receptor from honeybee (Apis mellifera) brain" J. Neurochem. 86, 725-735 doi.org/10.1046/j.1471-4159.2003.01876.x
 
*equally contributed